Photo by Ryan Coleman

Search Cheap Hotels in Sikeston

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Sikeston Cheap Hotels

Next weekend
In two weeks

Our top choices for Sikeston cheap hotels

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1001)
"Great stay"
United States
Heather
The price is Rp1.171.703
Rp1.321.869 total
includes taxes & fees
4 Jan - 5 Jan 2026
Pear Tree Inn Cape Girardeau West

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1003)
"Great place and staff, very accommodating!"
United States
Megan
The price is Rp1.506.523
Rp1.699.379 total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Plaza Hotel Cape Girardeau Conference Center

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (723)
"Room was good as usual. This is 4th stay over past 5 years. Only issue I had on this stay was the orange juice from breakfast options. "
United States
Todd
The price is Rp928.958
Rp1.058.781 total
includes taxes & fees
28 Dec - 29 Dec
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1000)
"This our favorite place to stop for a good night sleep. "
United States
Eileen
The price is Rp1.573.487
Rp1.809.032 total
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Inn & Suites Sikeston, MO

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very good, (1002)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is Rp1.265.452
Rp1.442.298 total
includes taxes & fees
28 Dec - 29 Dec
Best Western Plus Sikeston

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (686)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
The price is Rp990.732
Rp1.117.684 total
includes taxes & fees
8 Jan - 9 Jan 2026
Quality Inn Cape Girardeau North

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (390)
"Clean room, friendly staff and quiet stay."
United States
Margo
The price is Rp1.280.992
Rp1.438.400 total
includes taxes & fees
28 Dec - 29 Dec
Travelodge by Wyndham Dexter

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (614)
"Staff was great! Room was nice. "
United States
Lana
The price is Rp1.039.616
Rp1.153.715 total
includes taxes & fees
28 Dec - 29 Dec
Super 8 by Wyndham Charleston/Sikeston East MO

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is Rp1.523.431
Rp1.718.645 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (121)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is Rp894.639
Rp1.064.397 total
includes taxes & fees
29 Dec - 30 Dec
Country Yard Inn and Suite
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Sikeston Hotel Reviews

Frequently asked questions

What is Sikeston like for travellers on a budget?
Sikeston offers a variety of cheap accommodation options and things to do, making it a great getaway spot for budget travellers. You can find ways to save money while getting to know this destination, which is home to attractions such as Sikeston Depot Museum and Central Park.
What's the best place to stay on a budget in Sikeston?
Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi.
When is the best time for a budget trip to Sikeston?
Weather is probably a major factor when you plan your trip to Sikeston, but bear in mind that cheaper options are usually available when the weather isn't as good. The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.
What is there to see and do in Sikeston?
Sikeston attracts visitors with its major shopping area and fantastic dining options, and offers plenty to see and do without spending a fortune. You can budget for the local attractions that interest you most, and then make time for sights and activities that are easy on the wallet. If you're eager to get outdoors, you can enjoy the natural setting at Central Park, Shawnee National Forest or Mississippi River.
How can I get to Sikeston and get around on a budget?
Looking at these ways to get around Sikeston can help keep you on budget. The closest airport is Cairo, IL (CIR-Cairo Regional), 23.8 mi (38.3 km) away. If that doesn't suit your budget, the next closest is 24.2 mi (38.9 km) away: Cape Girardeau, MO (CGI-Cape Girardeau Municipal). Sikeston may not have many public transport options to choose from so renting a car could be an economical alternative to explore the area.