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Find hotels in Sikeston, MO from Rp1.075.609

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Our top choices for Sikeston hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
The price is Rp1.506.523
Rp1.699.379 total
includes taxes & fees
6 Jan - 7 Jan 2026
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1000)
"This our favorite place to stop for a good night sleep. "
United States
Eileen
The price is Rp1.508.682
Rp1.734.507 total
includes taxes & fees
30 Dec - 31 Dec
Drury Inn & Suites Sikeston, MO

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1001)
"Great stay"
United States
Heather
The price is Rp1.171.703
Rp1.321.869 total
includes taxes & fees
31 Dec - 1 Jan 2026
Pear Tree Inn Cape Girardeau West

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very good, (1010)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is Rp1.268.105
Rp1.445.322 total
includes taxes & fees
29 Dec - 30 Dec
Best Western Plus Sikeston

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (723)
"Room was good as usual. This is 4th stay over past 5 years. Only issue I had on this stay was the orange juice from breakfast options. "
United States
Todd
The price is Rp928.958
Rp1.058.781 total
includes taxes & fees
25 Jan - 26 Jan 2026
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (676)
"Great place "
United States
GUY
The price is Rp1.410.775
Rp1.526.811 total
includes taxes & fees
7 Jan - 8 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is Rp1.523.431
Rp1.718.645 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"Very friendly staff and great breakfast"
United States
Ray
The price is Rp1.506.523
Rp1.699.379 total
includes taxes & fees
6 Jan - 7 Jan 2026
Drury Inn & Suites Cape Girardeau

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (389)
"Clean room, friendly staff and quiet stay."
United States
Margo
The price is Rp1.280.686
Rp1.438.057 total
includes taxes & fees
28 Dec - 29 Dec
Travelodge by Wyndham Dexter

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is Rp2.095.625
Rp2.374.637 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Cape Girardeau Downtown

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (451)
"clean room, comfy bedding, nice staff, convenient location "
United States
Alexa
The price is Rp1.635.929
Rp1.852.280 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Sikeston

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1003)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is Rp1.389.336
Rp1.468.855 total
includes taxes & fees
28 Dec - 29 Dec
Drury Inn & Suites Jackson MO

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is Rp1.173.382
Rp1.323.764 total
includes taxes & fees
30 Dec - 31 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (142)
"Nice hotel, clean and comfortable "
United States
Laura
The price is Rp1.473.208
Rp1.661.985 total
includes taxes & fees
25 Jan - 26 Jan 2026
Fairfield Inn & Suites by Marriott Cape Girardeau

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1004)
"Everything was clean, staff was friendly "
United States
Matthew
The price is Rp1.255.408
Rp1.443.242 total
includes taxes & fees
25 Jan - 26 Jan 2026
Pear Tree Inn Sikeston

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (477)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is Rp1.614.469
Rp1.821.348 total
includes taxes & fees
28 Dec - 29 Dec
The Riverview

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (443)
"Staff was great. Hotel was clean. Great sleep. "
United States
Jeffrey
The price is Rp1.757.805
Rp1.990.274 total
includes taxes & fees
25 Jan - 26 Jan 2026
Holiday Inn Express & Suites Sikeston Southwest by IHG

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (686)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
The price is Rp965.664
Rp1.089.404 total
includes taxes & fees
1 Jan - 2 Jan 2026
Quality Inn Cape Girardeau North

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very good, (885)
"Room was clean and spacious."
United States
George
The price is Rp1.171.870
Rp1.414.110 total
includes taxes & fees
25 Jan - 26 Jan 2026
Candlewood Suites Cape Girardeau by IHG

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (282)
"Room was clean, breakfast was very good. "
United States
Connie
The price is Rp1.479.904
Rp1.686.722 total
includes taxes & fees
24 Jan - 25 Jan 2026
Comfort Inn & Suites Sikeston I-55
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Sikeston attractions

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

More cheap stays in Sikeston

Find out more about Sikeston

Top reasons to visit Sikeston

  • Outdoor Adventures: Sikeston boasts scenic landscapes and recreational areas perfect for exploration.
  • Family-Friendly Attractions: Enjoy a variety of attractions that cater to all ages, making it ideal for family visits.
  • Cultural Experiences: Attend vibrant art shows and visit local museums to immerse yourself in the rich culture.
  • Welcoming Accommodations: A diverse range of lodging options, including pet-friendly and accessible facilities, ensure a comfortable stay.
  • Charming Community: Experience the warmth of the local community and the heart of the American Midwest.

Find great hotels in Sikeston

Discover a range of welcoming accommodation options in Sikeston, Missouri, designed to cater to various traveller needs. From pet-friendly hotels to accessible amenities, there are diverse lodging types available, including motels and hotels. Whether you're on business or seeking an LGBTQIA-friendly getaway, Sikeston offers a comfortable stay for everyone. Explore the ideal accommodation sites to make your visit memorable.

  • Days Inn and Suites by Wyndham Sikeston: Experience comfort and convenience at Days Inn and Suites by Wyndham Sikeston, a pet-friendly haven ideal for both business travellers and holidaymakers. This hotel offers a welcoming environment with amenities tailored for furry friends, ensuring a stress-free stay for you and your pets. Guests appreciate the practical services, including a business centre and free Wi-Fi, making it an excellent choice for those combining work with leisure. The property’s strategic location allows easy access to local attractions, promising a delightful blend of relaxation and exploration.
  • Drury Inn & Suites Sikeston, MO: Drury Inn & Suites Sikeston, MO stands out as a family-friendly destination featuring thoughtful amenities for children, including complimentary cribs. This 3-star hotel is designed for both families and business travellers, effectively catering to a range of needs. Guests revel in the hotel's commitment to comfort, with spacious rooms and a variety of on-site facilities, ensuring your stay is both enjoyable and productive. The inviting atmosphere and convenient services make it a top choice for those looking to experience the best of Sikeston with their loved ones.
  • Best Western Plus Sikeston: Best Western Plus Sikeston offers a perfect blend of comfort and convenience for pet lovers. This hotel welcomes pets, allowing you to enjoy your vacation without leaving your furry companions behind. With a range of amenities designed for a pleasant stay, including free Wi-Fi and a delicious breakfast, guests can indulge in a homely atmosphere. The property’s prime location ensures easy access to local attractions, making it an excellent base for exploring Sikeston while enjoying the comforts of a well-appointed hotel.

Where to stay in and around Sikeston

For a delightful getaway, Sikeston, Missouri, offers a charming blend of outdoor adventures and family-friendly experiences. Embrace the scenic landscapes with ample rainfall and explore the vast swamplands nearby. Discover the warmth of the local community and indulge in excursions that showcase the heart of the American Midwest. Whether you're seeking relaxation or vibrant neighbourhoods, Sikeston promises memorable moments for every traveller.

  • Miner: Nestled adjacent to Sikeston, the charming village of Miner offers a delightful blend of cultural and outdoor experiences. With a steady flow of visitors year-round, the peak times in January and June to July attract those eager to explore its educational and recreational amenities. From modern college campuses to scenic campgrounds, Miner presents a welcoming atmosphere for those seeking both adventure and relaxation. The nearby tourist precinct and lively streets add to the village’s appeal, making it a perfect stop for culture enthusiasts and outdoor lovers alike.
  • Bertrand: Located a mere 12.9km from Sikeston, Bertrand is a hidden gem ideal for outdoor adventurers and nature lovers. With visitor numbers peaking in April, August, and during the festive season, this city offers a plethora of scenic landscapes waiting to be explored. The nearby national park, lush forests, and serene lake provide ample opportunities for hiking, picnicking, and appreciating the great outdoors. Bertrand’s tranquil environment and picturesque scenery make it a perfect retreat for those seeking an adventurous yet peaceful getaway.
  • Matthews: Also situated 12.9km from Sikeston, Matthews is known for its romantic ambiance and stunning outdoor vistas. This city’s popularity surges during the summer months, particularly from June to August, when visitors flock to enjoy its campgrounds and recreational areas. The proximity to a beautiful lake and the national state park ensures plenty of activities for nature enthusiasts. Additionally, the local history museum offers a glimpse into the area’s past, making Matthews a delightful destination for couples and families alike.

Things to do near Sikeston

Sikeston offers a delightful blend of outdoor activities, family-friendly attractions, and romantic getaways. Visitors can explore recreational areas, indulge in shopping at local centres, and enjoy educational experiences. A highlight includes the vibrant art shows that showcase local talent, making it a must-visit for culture enthusiasts. Whether you're seeking adventure or relaxation, Sikeston has something for everyone.

Shopping

Sikeston offers a variety of shopping experiences. Visit the Sikeston Outlet Mall for discounted brand-name goods. If you're up for a drive, head to Cape Girardeau's West Park Mall, where you can find a range of shops, from fashion to home decor.

Recreation

eDen Spa & Salon offers a rejuvenating body treatment experience, located 46.7km from Sikeston. This tranquil venue exudes wellness and relaxation vibes, making it an ideal retreat for visitors seeking to unwind and indulge in soothing therapies amidst a serene atmosphere.

Adventure

In Sikeston, experience the thrill of outdoor adventures at the nearby Lake Wappapello State Park, where you can hike scenic trails and partake in water sports. Additionally, visit the Sikeston Depot Museum to explore the rich history of the area while enjoying local festivals and events.

Nightlife

Sikeston's nightlife offers a charming blend of local pubs and vibrant venues. Enjoy live music at the Sikeston Jaycee Bootheel Rodeo grounds or unwind with friends at The Corner Pub. For a relaxed atmosphere, visit the local breweries for craft beers and delightful conversation.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Sikeston

To save money on your visit to Sikeston, plan your trip between November and January, when accommodation prices are lower compared to the peak months of April to June. Consider booking your stay on a Tuesday for the best rates, avoiding the more expensive Saturdays. Use Expedia to filter your hotel preferences and look for package deals that combine flights and activities for additional savings. Exploring the town on foot is also a budget-friendly option, allowing you to enjoy free attractions while keeping transport costs down.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Sikeston are November to January, where the prices are slightly lower. This is in comparison to April to June, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Sikeston is Tuesday. The most expensive day to stay in Sikeston is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to refine your preferences, such as your budget, preferred location, and the type of hotel you desire. To discover the most affordable prices and offers, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservation in Sikeston with your flights and activities through an Expedia package deal.

Find the best attractions in Sikeston

Sikeston, Missouri, offers a delightful blend of outdoor activities, family-friendly attractions, and romantic getaways. Visitors can explore local gems such as event venues, art museums, and urban parks, ensuring a rich cultural experience. Whether you're interested in business, outdoor adventures, or immersing yourself in the local culture, Sikeston provides a variety of points of interest that cater to every type of traveller.

  • City of Miner Convention Center: This modern event venue offers a professional atmosphere perfect for conferences and gatherings. It features versatile spaces that can host a variety of events, making it ideal for both business and social functions.
  • Sikeston Depot Museum: Immerse yourself in local history at this charming museum, where you can explore exhibits showcasing the rich culture of Sikeston. The museum, housed in a historic depot, provides a unique insight into the region's heritage.
  • Central Park: A delightful urban oasis, Central Park is perfect for families to enjoy outdoor activities. With lush greenery, playgrounds, and walking paths, it offers a relaxed atmosphere amidst the vibrant city life.

Best time to go to Sikeston

The best time to visit Sikeston can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Sikeston falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Sikeston falls in January, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January36.0°F (2.2°C)Light RainMostly SunnySlightly LowSlightly Low
February39.2°F (4.0°C)Light RainMostly SunnySlightly LowAverage
March49.5°F (9.7°C)Light RainMostly SunnyAverageAverage
April58.5°F (14.7°C)Light RainMostly SunnyAverageSlightly High
May68.2°F (20.1°C)Light RainMostly SunnyAverageSlightly High
June77.2°F (25.1°C)Light RainMostly SunnySlightly HighSlightly High
July79.5°F (26.4°C)Light RainMostly SunnySlightly HighAverage
August77.5°F (25.3°C)Light RainMostly SunnySlightly HighAverage
September72.1°F (22.3°C)Light RainMostly SunnyAverageAverage
October60.8°F (16.0°C)Light RainMostly SunnyAverageAverage
November48.6°F (9.2°C)Light RainMostly SunnyAverageSlightly Low
December41.2°F (5.1°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Sikeston

For visitors heading to Sikeston, Missouri, there are several nearby airports to consider. Paducah, KY (PAH-Barkley Regional) is approximately 75.6km away, with notable hotels such as the Garner Hotel Paducah West and Red Roof Inn Paducah, both within 8.0km of the airport. Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is closer at 38.6km from Sikeston, offering accommodations like the Drury Plaza Hotel and Courtyard by Marriott, both 9.7km away. Cairo, IL (CIR-Cairo Regional) is also 38.6km distant, featuring the Quality Inn Cairo I-57 just 3.2km from the airport. Each of these locations provides various transport options for convenient access to and from the airports.

Frequently asked questions

Where is the best place to stay in Sikeston?
Fairfield Inn & Suites by Marriott Sikeston is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Other top choices based on reviews include Pear Tree Inn Sikeston and Drury Inn & Suites Sikeston, MO. See all available top hotels, or vacation rentals in Sikeston.
If I need to cancel my hotel reservation in Sikeston, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.
What's the best budget-friendly hotel in Sikeston?
Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Sikeston.
What's the best family accommodation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your family trip. Find more child-friendly accommodations in Sikeston.
What's the best LGBTQ-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Sikeston.
What's the best dog-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top hotel for people travelling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good choices for you and your pet's trip include Hampton Inn Sikeston and Pear Tree Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.
What are some hotels with pools in Sikeston?
Best Western Plus Sikeston is a top hotel with a pool, free full breakfast and free self-parking. TownePlace Suites by Marriott Sikeston is another choice with an on-site pool. View all hotels with pools in Sikeston.
What is staying in Sikeston like?
Families will find child-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodation options to choose from. Find out more about Sikeston.
What is there to see in Sikeston?
A couple of favourite places to visit are Sikeston Depot Museum and Central Park. You'll also find River Ridge Winery and Front Street Studio & Art Gallery in the area. Take a look at what more there is to see and do in Expedia's Sikeston guide.
What's the seasonal weather in Sikeston?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.

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