The Best Hotels Closest to Sikeston Depot Museum in Sikeston - 2026 Updated Prices

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Our top choices for Sikeston Depot Museum hotels

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

1. Fairfield Inn & Suites by Marriott Sikeston

2.4 km from Sikeston Depot Museum

Allen

Rp1.808.203

Rp2.047.338 total

includes taxes & fees

4 Oct - 5 Oct

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

2. TownePlace Suites by Marriott Sikeston

2.3 km from Sikeston Depot Museum

Stacy

Rp1.790.300

Rp2.027.067 total

includes taxes & fees

4 Oct - 5 Oct

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

3. Hampton Inn Sikeston

2.3 km from Sikeston Depot Museum

John

Rp1.820.377

Rp2.061.122 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A conference room with a long table, multiple chairs, and a television screen on the wall.

A kitchenette with a coffee machine, a kettle, and storage shelves.

A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

2.1 km from Sikeston Depot Museum

Melissa

Rp1.700.785

Rp1.925.713 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

5. Drury Inn & Suites Sikeston, MO

5.1 km from Sikeston Depot Museum

Scott

Rp1.682.703

Rp1.934.688 total

includes taxes & fees

1 Oct - 2 Oct

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

6. Best Western Plus Sikeston I-55

5.4 km from Sikeston Depot Museum

Shelley

Rp1.560.963

Rp1.779.108 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

A Travel Inn and Suites with a brick facade, a flat roof, and a welcoming entrance.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

5 km from Sikeston Depot Museum

Sharika West

Rp1.244.079

Rp1.417.940 total

includes taxes & fees

27 Sept - 28 Sept

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

8. Comfort Inn & Suites Sikeston I-55

4.9 km from Sikeston Depot Museum

Starlette

Rp1.582.625

Rp1.803.797 total

includes taxes & fees

4 Oct - 5 Oct

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

9. Days Inn and Suites by Wyndham Sikeston

5.4 km from Sikeston Depot Museum

David

Rp1.187.148

Rp1.353.052 total

includes taxes & fees

29 Sept - 30 Sept

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A motel with a covered entrance, multiple rooms, and a parking lot.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

10. Super 8 by Wyndham Sikeston/Miner Area

4.7 km from Sikeston Depot Museum

William

Rp1.022.619

Rp1.165.530 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

A bathroom with a bathtub, toilet, and shower curtain.

A reception area with a counter, a coffee machine, and seating.

11. Country Yard Inn and Suite

5.5 km from Sikeston Depot Museum

William

Rp1.097.096

Rp1.305.270 total

includes taxes & fees

27 Sept - 28 Sept

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Compare popular hotels close to Sikeston Depot Museum

Property	Property class	Guest rating
Fairfield Inn & Suites by Marriott Sikeston	9.4 Exceptional 113 reviews	View
TownePlace Suites by Marriott Sikeston	9.4 Exceptional 26 reviews	View
Hampton Inn Sikeston	9.0 Wonderful 624 reviews	View
Holiday Inn Express & Suites Sikeston Southwest by IHG	8.8 Excellent 509 reviews	View
Drury Inn & Suites Sikeston, MO	9.6 Exceptional 1,001 reviews	View

Top Sikeston Depot Museum Hotel Reviews

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

10/10 Excellent

"It has been updated somewhat but is still an older building. I don't think carpets are ever clean enough. The staff is always friendly and helpful. I love staying here."

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent

"I have always have a great stay each time I’ve been here. Beds comfortable and rooms very clean."

Econo Lodge Dexter

10/10 Excellent

"Quick check in and very professional and polite staff. Room was clean and quite good place to stay and get some rest. Multiple restaurants and stores close by very easy access to almost everything including medical"

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Clean room and perfect stay. We have come to consistently appreciate Drury brand for a quality stay. We would definitely recommend this location for clean comfortable accommodations."

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent

"Súper affordable pricing, and the property was clean and comfortable! Complimentary breakfast was a plus!"

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"This was a very good value. It has been the best hotel I've stayed at in awhile."

TownePlace Suites by Marriott Sikeston

10/10 Excellent

"My overall experience was amazing from the time I checked in until I left. The staff were super pleasant and incredible. My room was clean and spacious. I never been in an extended stay room before. I definitely will be booking a suite like this one again."

The Riverstone Hotel Charleston-Sikeston

8/10 Good

"Overall it was excellant, other then the toilet running constantly... Pool could have been cleaner, considering the heat-wave they were having............."

Eagle Inn Charleston

10/10 Excellent

"Great"

Other attractions near Sikeston Depot Museum

Central Park

7.2/10 (56 reviews)

Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savour the top-notch restaurants.

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City of Miner Convention Center

Learn about the events happening in City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savour the top-notch restaurants.

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Front Street Studio & Art Gallery

8.6/10 (15 reviews)

You can spend time browsing the exhibits at Front Street Studio & Art Gallery during your travels in Blodgett. While in this relaxing area, you can savour the top-notch restaurants.

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Hunter-Dawson State Historic Site

7.6/10 (13 reviews)

You can browse the exhibits at Hunter-Dawson State Historic Site, a museum with a story of its own, during your trip to New Madrid. Amble around the area's parks or experience its museums.

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River Ridge Winery

8.4/10 (15 reviews)

You can enjoy a tasting or tour at River Ridge Winery during your travels to New Madrid. Amble around the area's parks or experience its museums.

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New Madrid Historical Museum

8.2/10 (36 reviews)

You can study the exhibits at New Madrid Historical Museum, a museum with a storied past, during your travels to New Madrid. Amble around the area's parks or experience its museums.

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Dexter Welcome Center Depot and Museum

7.6/10 (12 reviews)

You can study the exhibits at Dexter Welcome Center Depot and Museum, a museum with a story of its own, during your holiday in Dexter. While in this family-friendly area, you can enjoy the restaurants.

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The Heritage House

8.4/10 (7 reviews)

Learn about the local history of Dexter with a stop at The Heritage House. While in this family-friendly area, you can enjoy the restaurants.

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Frequently asked questions

What's the area like around Sikeston Depot Museum?

Sikeston Depot Museum is located in a welcoming area of Sikeston known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 5 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Sikeston Depot Museum?

Drury Inn & Suites Sikeston, MO is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. It's located 3.2 mi (5.1 km) from Sikeston Depot Museum. Other good choices within 5 miles include Hampton Inn Sikeston and Days Inn and Suites by Wyndham Sikeston.

How many hotels will I find close to Sikeston Depot Museum?

Expedia has 5 hotels and other accommodation options within a mile from Sikeston Depot Museum.

If I need to cancel the hotel reservation for my stay near Sikeston Depot Museum, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best options available near Sikeston Depot Museum.

Search Hotels Near Sikeston Depot Museum, Sikeston

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Our top choices for Sikeston Depot Museum hotels

1. Fairfield Inn & Suites by Marriott Sikeston

2. TownePlace Suites by Marriott Sikeston

3. Hampton Inn Sikeston

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

5. Drury Inn & Suites Sikeston, MO

6. Best Western Plus Sikeston I-55

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8. Comfort Inn & Suites Sikeston I-55

9. Days Inn and Suites by Wyndham Sikeston

10. Super 8 by Wyndham Sikeston/Miner Area

11. Country Yard Inn and Suite

Compare popular hotels close to Sikeston Depot Museum

Top Sikeston Depot Museum Hotel Reviews

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Holiday Inn Express & Suites Sikeston Southwest by IHG

Econo Lodge Dexter

Drury Inn & Suites Sikeston, MO

Super 8 by Wyndham Charleston/Sikeston East MO

Days Inn and Suites by Wyndham Sikeston

TownePlace Suites by Marriott Sikeston

The Riverstone Hotel Charleston-Sikeston

Eagle Inn Charleston

Other attractions near Sikeston Depot Museum

Central Park

City of Miner Convention Center

Front Street Studio & Art Gallery

Hunter-Dawson State Historic Site

River Ridge Winery

New Madrid Historical Museum

Dexter Welcome Center Depot and Museum

The Heritage House

Frequently asked questions