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Our top choices for Southern Illinois Healthcare hotels

Home2 Suites by Hilton Carbondale

Home2 Suites by Hilton Carbondale
3.0 star property
2.8 km from Southern Illinois Healthcare
8.8 out of 10, Excellent, (510)
"Great location. Nice, new hotel. Spacious room."
United States
Sabrina
The price is Rp1.600.896
Rp1.840.711 total
includes taxes & fees
28 Dec - 29 Dec
Home2 Suites by Hilton Carbondale

Holiday Inn Carbondale-Conference Center by IHG

Holiday Inn Carbondale-Conference Center by IHG
3.0 star property
2.5 km from Southern Illinois Healthcare
8.8 out of 10, Excellent, (640)
"Great staff!"
United States
Greg
The price is Rp1.784.332
Rp2.051.648 total
includes taxes & fees
22 Dec - 23 Dec
Holiday Inn Carbondale-Conference Center by IHG

Hampton Inn Carbondale

Hampton Inn Carbondale
2.5 star property
2.1 km from Southern Illinois Healthcare
8.4 out of 10, Very good, (611)
"Room was spotless, check in was quick, all personnel were courteous. "
United States
William
The price is Rp1.854.371
Rp2.132.157 total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn Carbondale

Best Western Saluki Inn

Best Western Saluki Inn
2.5 star property
0.2 km from Southern Illinois Healthcare
8.0 out of 10, Very good, (1002)
"It was fine for the price and location. Good value if all you need is a no frills hotel room, and much better since the re-model. Clean room and staff was friendly and courteous. Easy walk to Buffalo Wild Wings and Fujiyama Japanese Steak House and a few others. Would stay there again."
United States
Douglas
The price is Rp1.318.071
Rp1.548.870 total
includes taxes & fees
24 Dec - 25 Dec
Best Western Saluki Inn

Comfort Inn & Suites Carbondale University Area

Comfort Inn & Suites Carbondale University Area
2.5 star property
2.6 km from Southern Illinois Healthcare
7.6 out of 10, Good, (516)
"Our room was clean and our stay was comfortable. We were not expecting a 5 star hotel due to the price and felt we received a good value for what we paid. We would stay again."
United States
James
The price is Rp1.247.365
Rp1.434.221 total
includes taxes & fees
24 Dec - 25 Dec
Comfort Inn & Suites Carbondale University Area

Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale
2.0 star property
0.8 km from Southern Illinois Healthcare
7.4 out of 10, Good, (1001)
"Room was clean but a bit dated. "
United States
Giovanni
The price is Rp917.180
Rp1.054.574 total
includes taxes & fees
11 Dec - 12 Dec
Super 8 by Wyndham Carbondale

Quality Inn Carbondale University area

Quality Inn Carbondale University area
2.5 star property
0.3 km from Southern Illinois Healthcare
5.8 out of 10, (835)
"This was a good place to stay"
United States
Ronald
The price is Rp905.007
Rp1.040.576 total
includes taxes & fees
8 Jan - 9 Jan 2026
Quality Inn Carbondale University area

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
4.5 star property
8.3 km from Southern Illinois Healthcare
9.4 out of 10, Exceptional, (386)
"Great place!!"
United States
Jeff
Walker's Bluff Casino Resort

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
12.6 km from Southern Illinois Healthcare
9.4 out of 10, Exceptional, (511)
"great property, great breakfast, friendly and knowledgable staff."
United States
Ronald
The price is Rp1.786.365
Rp1.982.508 total
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57
2.5 star property
19.3 km from Southern Illinois Healthcare
9.4 out of 10, Exceptional, (1002)
"Very clean room, friendly staff, and the breakfast was tasty. Will stay there again"
United States
Marcus
The price is Rp1.801.008
Rp2.160.850 total
includes taxes & fees
5 Jan - 6 Jan 2026
Comfort Inn & Suites Marion I-57

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
19.4 km from Southern Illinois Healthcare
9.4 out of 10, Exceptional, (1002)
"Hotel is very clean and staff is also friendly."
United States
Tonya
The price is Rp1.083.773
Rp1.300.394 total
includes taxes & fees
2 Jan - 3 Jan 2026
Drury Inn & Suites Marion

Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL
2.5 star property
19.5 km from Southern Illinois Healthcare
8.6 out of 10, Excellent, (1000)
"Room was nice and staff was friendly."
United States
MING
The price is Rp1.615.904
Rp1.938.761 total
includes taxes & fees
1 Jan - 2 Jan 2026
Country Inn & Suites by Radisson, Marion, IL

Baymont by Wyndham Marion

Baymont by Wyndham Marion
2.5 star property
19.7 km from Southern Illinois Healthcare
8.4 out of 10, Very good, (1065)
"This place was nice for the money and our 1 night stay. "
United States
Charles
The price is Rp1.299.060
Rp1.558.611 total
includes taxes & fees
1 Jan - 2 Jan 2026
Baymont by Wyndham Marion

Fairfield Inn and Suites by Marriott Marion

Fairfield Inn and Suites by Marriott Marion
2.5 star property
19.6 km from Southern Illinois Healthcare
8.4 out of 10, Very good, (358)
"The room was clean and comfortable bed"
United States
Marilee
The price is Rp1.467.488
Rp1.760.692 total
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn and Suites by Marriott Marion

Super 8 by Wyndham Marion

Super 8 by Wyndham Marion
2.0 star property
19.7 km from Southern Illinois Healthcare
7.6 out of 10, Good, (1002)
"Decent room for the cost compared to others."
United States
Nicole
The price is Rp1.234.024
Rp1.480.581 total
includes taxes & fees
15 Dec - 16 Dec
Super 8 by Wyndham Marion

Motel 6 Marion, IL

Motel 6 Marion, IL
2.0 star property
15.7 km from Southern Illinois Healthcare
7.2 out of 10, Good, (607)
"This is a no frills motel that offers great value for the money! I found it to be safe, quiet and convenient to dining, shopping and several nearby towns. Would not hesitate to stay here again! The owner and staff work hard to ensure a pleasant stay!"
United States
Charles
The price is Rp1.000.393
Rp1.110.288 total
includes taxes & fees
16 Dec - 17 Dec
Motel 6 Marion, IL

Quality Inn & Suites Marion

Quality Inn & Suites Marion
2.5 star property
19.9 km from Southern Illinois Healthcare
7.4 out of 10, Good, (1001)
"Clean room. Friendly staff. My 2nd stay here. Good room for the price. Would stay here again. "
United States
Rodney
The price is Rp978.047
Rp1.173.462 total
includes taxes & fees
8 Jan - 9 Jan 2026
Quality Inn & Suites Marion

University Inn of Carbondale

University Inn of Carbondale
2.5 star property
5.3 km from Southern Illinois Healthcare
6.0 out of 10, (325)
"Yes everything was great"
United States
Jesse
University Inn of Carbondale

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Holiday Inn Express Hotel & Suites Marion Northeast by IHG
2.5 star property
19.8 km from Southern Illinois Healthcare
9.0 out of 10, Wonderful, (925)
"yes the room was great and the staff was great! "
United States
Amador
The price is Rp1.617.572
Rp1.940.753 total
includes taxes & fees
9 Jan - 10 Jan 2026
Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southern Illinois Healthcare Hotel Reviews

Hotels near other Southern Illinois Healthcare attractions

Frequently asked questions

What's the area like around Southern Illinois Healthcare?
Southern Illinois Healthcare is located in Carbondale. This family-friendly area is known for its array of dining options and major shopping area. You'll find 63 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay close to Southern Illinois Healthcare?
Adjacent to Southern Illinois Healthcare, Best Western Saluki Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good options close by include Super 8 by Wyndham Carbondale and Quality Inn Carbondale University area.
How many hotels should I expect to find close to Southern Illinois Healthcare?
Expedia has 63 hotels and other accommodation options a few miles from Southern Illinois Healthcare.
If I need to cancel the hotel reservation for my stay near Southern Illinois Healthcare, will I receive a refund?
Yes! The majority of hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to view the top deals on offer near Southern Illinois Healthcare.