Search Family-Friendly Hotels in St. Charles

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on St. Charles Family-Friendly Hotels

Next weekend
In two weeks

Our top choices for St. Charles family-friendly hotels

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1009)
"very friendly staff and good location "
United States
Heather
The price is Rp1.496.668
Rp1.720.075 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn St. Charles St. Peters

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1004)
"Everything was great!"
United States
Rita
The price is Rp1.869.579
Rp2.148.651 total
includes taxes & fees
25 Jan - 26 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1000)
"Nice staff at reception. "
United States
Denise
The price is Rp1.324.027
Rp1.521.664 total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites St Charles - St Louis

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1002)
"Staff and hotel were amazing"
United States
Allison
The price is Rp1.925.508
Rp2.232.109 total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Plaza Hotel St. Louis St. Charles

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
St. Charles
6.6 out of 10, (1005)
"Air conditioning worked and staff were nice"
United States
Kimberly
The price is Rp1.054.935
Rp1.212.338 total
includes taxes & fees
29 Dec - 30 Dec
Relax Inn Saint Charles

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
St. Charles
9.2 out of 10, Wonderful, (637)
"Huge room. Great breakfast. "
United States
David
The price is Rp1.813.651
Rp2.186.236 total
includes taxes & fees
25 Jan - 26 Jan 2026
Hampton Inn & Suites St. Charles Old Town Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Charles Hotel Reviews

Frequently asked questions

What's St. Charles like for family-friendly holidays?
The historic destination of St. Charles is a good choice if you've been thinking about a trip with your children. The theatres and restaurants are just a couple of things that make this the ideal place for a family holiday. Arrange a flight into Lambert-St. Louis International Airport (STL), which is the closest airport, or St. Louis, MO (SUS-Spirit of St. Louis), which is located 11.7 mi (18.9 km) from the city centre.
What's the best family accommodation in St. Charles?
Country Inn & Suites by Radisson, St. Charles Historic District is a hotel with an indoor pool and free parking, and it's a top choice on Expedia for families. Other good choices for your stay with the children include Drury Plaza Hotel St. Louis St. Charles and Hampton Inn & Suites St. Charles Old Town Area.
How many hotels that welcome families will I be able to find in St. Charles?
Expedia has 9 family-friendly hotels and other accommodation options in St. Charles.
When's the best time to book a family-friendly holiday in St. Charles?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.
What's there to see and do with your family in St. Charles?
While you are visiting St. Charles, you may want to round up the youngsters and make time to see interesting attractions such as Lewis & Clark Boathouse and Nature Center, Fast Lane Classic Cars and Family Arena. Make sure that you have lots of time for activities such as Weldon Spring Site Interpretive Center and Missouri Artists on Main.