Midtown Travel Guide

St. Louis

Midtown
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Photo by Karissa Krull
Photo by Linda Garrison
Photo by Sophie R

Popular places to visit

Things to do


Top hotels in Midtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave, St. Louis, MO
The price is Rp1.826.220 per night from 9 Nov to 10 Nov
Rp1.826.220
Rp2.171.906 total
9 Nov - 10 Nov
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a 24-hour fitness centre and parking (surcharge). Our guests praise the breakfast ...
7.8/10 Good! (1,000 reviews)
Enjoyed our room
Love the 2 bedroom reservation: one bedroom with a king bed as well as a bathroom with the 2nd bedroom with 2 double beds as well with a bathroom. Love the couch, TV area as well as a kitchen. With my daughter having celiac, we must carry food safe for her to eat. The full sized fridge was great ...

Reviewed on 14 Oct 2025

Residence Inn by Marriott St Louis Downtown
Element St. Louis Midtown

Element St. Louis Midtown

3 out of 5
3763 Forest Park Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is Rp2.241.270 per night from 30 Oct to 31 Oct
Rp2.241.270
Rp2.620.694 total
30 Oct - 31 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and ...
9/10 Wonderful! (608 reviews)
EVERY single staff member I came in contact with was super friendly and accommodating. Place was great location, nice breakfast and clean comfortable rooms.

Reviewed on 21 Oct 2025

Element St. Louis Midtown
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is Rp2.390.522 per night from 30 Oct to 31 Oct
Rp2.390.522
Rp2.795.214 total
30 Oct - 31 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,181 reviews)
Check-in was great. Staff very knowledgable of the area and was helpful in offering dinner options around town as well as complimentary dinner at the hotel. Parking garage is limited to guests. Bartender was friendly. 1st time guest, will definitely return!

Reviewed on 20 Oct 2025

Drury Plaza Hotel St. Louis at the Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
The price is Rp1.660.200 per night from 2 Nov to 3 Nov
Rp1.660.200
Rp1.938.117 total
2 Nov - 3 Nov
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,969 reviews)
Excellent

Reviewed on 24 Oct 2025

Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
The price is Rp1.643.598 per night from 25 Nov to 26 Nov
Rp1.643.598
Rp1.938.278 total
25 Nov - 26 Nov
includes taxes & fees
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,988 reviews)
So nice to be directly next to the Arch. I went out for an early bike ride and got Coffee and enjoyed the park. Only real negative was the valet was super backed up and parking garage was full so after an 11 hour drive I had to go find parking blocks away in not the best area. Also, no room service ...

Reviewed on 24 Oct 2025

Hyatt Regency St. Louis at The Arch
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive, Fenton, MO
The price is Rp1.411.170 per night from 2 Nov to 3 Nov
Rp1.411.170
Rp1.629.984 total
2 Nov - 3 Nov
includes taxes & fees
Stay at this 3-star business-friendly hotel in Fenton. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,035 reviews)
My stay was generally good! I had no major issues throughout. My only concern was the TV guide was (at least my assigned room) was not up to date and many channels were no signal. That was really the only inconvenience although I wasn’t much at the hotel to fully utilize this amenity. Still a good ...

Reviewed on 19 Oct 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Midtown

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The Gate

While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.

The Gate
St. Louis showing interior views

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Downtown West
Lafayette Square featuring a house and a park

Lafayette Square

The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.

Lafayette Square
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Shaw

Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.

Shaw
Central West End

Central West End

4.5/5(2 area reviews)

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Central West End
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The Grove

While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.

The Grove


Midtown Travel Guide