The Best Hotels in Uptown, Collinsville - 2026 Updated Prices

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Our top choices for Uptown hotels

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

1. Drury Inn & Suites St. Louis Collinsville

Eastport, 2.6 km from Uptown

Amanda

Rp2.044.602 total

includes taxes & fees

22 Nov - 23 Nov

A reception area with a wooden reception desk, a stone wall with a clock, and framed pictures on the wall.

2. Comfort Inn Collinsville near St. Louis

Eastport, 2.7 km from Uptown

Chessy

Rp2.069.849 total

includes taxes & fees

26 Nov - 27 Nov

A lobby with a central table displaying vases, a stone wall with mirrors, and a seating area with sofas and chairs.

3. DoubleTree by Hilton Collinsville - St. Louis

Eastport, 2.6 km from Uptown

katie

Rp2.270.158 total

includes taxes & fees

1 Dec - 2 Dec

A multi-story hotel with a covered entrance, stone pillars, and a parking lot.

4. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Eastport, 2.9 km from Uptown

Paul

Rp1.933.181 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel lobby with a central dining area, seating arrangements, and a television screen.

5. Holiday Inn Express Troy by IHG

10 km from Uptown

Todd

Rp2.297.046 total

includes taxes & fees

29 Nov - 30 Nov

A hotel room with two beds, a desk, a chair, and a TV.

6. Hampton Inn Collinsville

Eastport, 2.7 km from Uptown

Jeffrey

Rp2.110.537 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel room with a large bed, a blue chair, and a wall-mounted TV.

7. Days Inn by Wyndham Collinsville/St. Louis

Eastport, 2.7 km from Uptown

Gary

Rp1.330.170 total

includes taxes & fees

10 Nov - 11 Nov

A modern living room with a sofa, chairs, a coffee station, and a dining area.

8. Best Western St. Louis Fairview Heights

7.3 km from Uptown

Jacob

Rp1.812.420 total

includes taxes & fees

8 Nov - 9 Nov

A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.

9. Hampton Inn O'Fallon

10.9 km from Uptown

Edmond

Rp2.397.241 total

includes taxes & fees

15 Nov - 16 Nov

A modern hotel lobby with a sofa, chairs, a round table, and a decorative wall with geometric patterns.

10. Holiday Inn St. Louis Fairview Heights by IHG

7.3 km from Uptown

Julia

Rp2.337.334 total

includes taxes & fees

18 Nov - 19 Nov

A modern lounge area with a sectional sofa, ottomans, and a round table.

11. Drury Inn & Suites St. Louis Fairview Heights

7.2 km from Uptown

Christopher

Rp1.845.019 total

includes taxes & fees

16 Nov - 17 Nov

A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

12. Comfort Inn Edwardsville - St. Louis

10.9 km from Uptown

Christina

Rp1.703.463 total

includes taxes & fees

29 Nov - 30 Nov

A hotel room with two beds, each with a headboard, bedside tables, lamps, and a desk with a chair.

13. Econo Lodge Inn & Suites Fairview Heights - St. Louis

7.2 km from Uptown

Linda

Rp1.310.929 total

includes taxes & fees

2 Dec - 3 Dec

A hotel room with a bed, two bedside lamps, a cityscape painting, a wooden headboard, and a brown chair.

14. Super 8 by Wyndham Collinsville St. Louis

Eastport, 2.8 km from Uptown

stephen

Rp1.454.320 total

includes taxes & fees

9 Nov - 10 Nov

A Holiday Inn Express & Suites hotel with a covered entrance and a brick facade.

15. Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

11.9 km from Uptown

Rafal

Rp1.973.674 total

includes taxes & fees

30 Nov - 1 Dec

A modern living room with a fireplace, comfortable seating, and a flat-screen TV mounted on the wall.

16. Radisson Hotel Fairview Heights - St. Louis

7 km from Uptown

SONIA

Rp1.725.283 total

includes taxes & fees

16 Nov - 17 Nov

A lobby with checkered armchairs, a reception desk, a plant, and a tiled floor.

17. Americas Best Value Inn Collinsville St. Louis

2.3 km from Uptown

Shewanna

Rp1.333.961 total

includes taxes & fees

11 Nov - 12 Nov

An outdoor patio with tables and chairs, a brick building, and a parking lot in the background.

18. Fairfield Inn & Suites by Marriott O'Fallon, IL

11.4 km from Uptown

Mohamad

Rp2.891.322 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with a fireplace, a large painting, and multiple hanging light fixtures.

19. Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

10.8 km from Uptown

Carlos

Rp2.307.792 total

includes taxes & fees

9 Nov - 10 Nov

A hotel room with two beds, each with a wooden headboard, white bedding, and a blue throw blanket. There is a nightstand with a lamp between the beds, and a framed picture on the wall.

20. Comfort Suites Fairview Heights - St. Louis

7.2 km from Uptown

Demond

Rp1.459.777 total

includes taxes & fees

23 Nov - 24 Nov

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Compare popular hotels in Uptown

Property	Property class	Guest rating
Drury Inn & Suites St. Louis Collinsville	3.0 star property	9.6 Exceptional 1,003 reviews	View
Holiday Inn Express Troy by IHG	2.5 star property	9.4 Exceptional 846 reviews	View
Comfort Inn Collinsville near St. Louis	2.5 star property	8.6 Excellent 1,003 reviews	View
Hampton Inn O'Fallon	2.5 star property	9.2 Wonderful 888 reviews	View
DoubleTree by Hilton Collinsville - St. Louis	4.0 star property	8.2 Very good 1,001 reviews	View

Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

While visiting Eastport, you might make a stop by sights like Splash City Family Waterpark and Gateway Conference Center.

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Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.

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A large, historic building with arched windows and a prominent corner entrance.

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.

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Top Uptown Hotel Reviews

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"Whenever we are in St. Louis overnight this is our preferred hotel. Always clean, nice amenities, excellent location and a great breaakfast to get you get you up and going in the morning!"

21C Museum Hotel St Louis

10/10 Excellent

"My boyfriend & I stayed here for our anniversary since we usually spend them at home, and this was the best hotel for a staycation! From the hotel, to even restaurant staff, everyone was so pleasant. We had a Luxury King Suite and it was absolutely beautiful. We decided this hotel will become a place we start to return to for future anniversaries and I couldn’t be more excited! While we went out for Halloween and only stayed for 1 night, we never got to actually take a moment to enjoy some the of the main hotel amenities but still had the best time and we have already recommended it to others!"

Frequently asked questions

What is Uptown like?

Travellers to the Uptown neighbourhood in Collinsville will be sure to enjoy their stay. Are you looking for Uptown travel tips? Make sure that you visit Kruta Bakery and World's Largest Catsup Bottle while you're in the neighbourhood.

If I need to cancel my hotel reservation in Uptown, will I receive a refund?

Yes! Most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer in Uptown.

What is there to do in this Collinsville neighbourhood?

A few attractions you might want to check out while you're in Uptown are Kruta Bakery and World's Largest Catsup Bottle. While you're out sightseeing, Gateway Conference Center and Gateway Fun Park are a couple of additional sights to visit in Collinsville.

Search Hotels in Uptown, Collinsville

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Our top choices for Uptown hotels

1. Drury Inn & Suites St. Louis Collinsville

2. Comfort Inn Collinsville near St. Louis

3. DoubleTree by Hilton Collinsville - St. Louis

4. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

5. Holiday Inn Express Troy by IHG

6. Hampton Inn Collinsville

7. Days Inn by Wyndham Collinsville/St. Louis

8. Best Western St. Louis Fairview Heights

9. Hampton Inn O'Fallon

10. Holiday Inn St. Louis Fairview Heights by IHG

11. Drury Inn & Suites St. Louis Fairview Heights

12. Comfort Inn Edwardsville - St. Louis

13. Econo Lodge Inn & Suites Fairview Heights - St. Louis

14. Super 8 by Wyndham Collinsville St. Louis

15. Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

16. Radisson Hotel Fairview Heights - St. Louis

17. Americas Best Value Inn Collinsville St. Louis

18. Fairfield Inn & Suites by Marriott O'Fallon, IL

19. Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

20. Comfort Suites Fairview Heights - St. Louis

Compare popular hotels in Uptown

Where to stay in Uptown

Eastport

Mulberry Hills

Historic Downtown Collinsville

Top Uptown Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Frequently asked questions