The Best Hotels in Uptown, Collinsville - 2026 Updated Prices

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Our top choices for Uptown hotels

1. Americas Best Value Inn Collinsville St. Louis

2.3 km from Uptown

Jason

Rp1.115.869 total

includes taxes & fees

5 Oct - 6 Oct

2. Drury Inn & Suites St. Louis Collinsville

Eastport, 2.6 km from Uptown

Lisa

Rp2.247.451 total

includes taxes & fees

20 Sept - 21 Sept

3. Days Inn by Wyndham Collinsville/St. Louis

Eastport, 2.7 km from Uptown

Brian Lee

Rp1.273.872 total

includes taxes & fees

20 Sept - 21 Sept

4. Comfort Inn Collinsville near St. Louis

Eastport, 2.7 km from Uptown

Jose Rene

Rp1.998.994 total

includes taxes & fees

12 Oct - 13 Oct

5. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Eastport, 2.9 km from Uptown

Gireesh Kumar

Rp1.755.398 total

includes taxes & fees

20 Sept - 21 Sept

6. Super 8 by Wyndham Collinsville St. Louis

Eastport, 2.8 km from Uptown

Anthony

Rp1.184.574 total

includes taxes & fees

20 Sept - 21 Sept

7. Hampton Inn Collinsville

Eastport, 2.7 km from Uptown

Ria

Rp2.108.744 total

includes taxes & fees

20 Sept - 21 Sept

8. Best Western Troy Hotel

10.1 km from Uptown

joshua

Rp1.741.627 total

includes taxes & fees

15 Sept - 16 Sept

9. Holiday Inn St. Louis Fairview Heights by IHG

7.3 km from Uptown

Valerie

Rp2.347.899 total

includes taxes & fees

20 Sept - 21 Sept

Standard King Room with Whirlpool - Non Smoking

10. Quality Inn O'Fallon - St. Louis - Shiloh

9 km from Uptown

Laura

Rp1.327.331 total

includes taxes & fees

16 Sept - 17 Sept

11. Holiday Inn Express Troy by IHG

10 km from Uptown

Donald

Rp2.149.915 total

includes taxes & fees

20 Sept - 21 Sept

12. Drury Inn & Suites St. Louis Fairview Heights

7.2 km from Uptown

Orbie

Rp1.790.523 total

includes taxes & fees

20 Sept - 21 Sept

13. Red Roof Inn St Louis - Troy, IL

10.1 km from Uptown

crystal

Rp1.266.583 total

includes taxes & fees

27 Sept - 28 Sept

14. Comfort Suites Fairview Heights - St. Louis

7.2 km from Uptown

Josh

Rp1.558.326 total

includes taxes & fees

27 Sept - 28 Sept

15. Radisson Hotel Fairview Heights - St. Louis

7 km from Uptown

Clint

Rp1.623.388 total

includes taxes & fees

20 Sept - 21 Sept

16. Super 8 by Wyndham Troy IL/St. Louis Area

9.9 km from Uptown

Esmeralda

Rp1.329.038 total

includes taxes & fees

20 Sept - 21 Sept

17. Fairfield Inn & Suites by Marriott O'Fallon, IL

11.4 km from Uptown

Mohamad

Rp2.805.922 total

includes taxes & fees

27 Sept - 28 Sept

18. Pear Tree Inn St. Louis Near Union Station

19.6 km from Uptown

LaSonia

Rp2.409.101 total

includes taxes & fees

20 Sept - 21 Sept

19. DoubleTree by Hilton Collinsville - St. Louis

Eastport, 2.6 km from Uptown

Jenni

Rp2.822.729 total

includes taxes & fees

15 Oct - 16 Oct

20. Best Western Plus MidAmerica Hotel

19.9 km from Uptown

Justin

Rp2.198.941 total

includes taxes & fees

27 Sept - 28 Sept

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Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.

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Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.

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A large, historic building with arched windows and a prominent corner entrance.

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.

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Top Uptown Hotel Reviews

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"Nice hotel very clean and safe area to stay"

21C Museum Hotel St Louis

10/10 Excellent

"My partner and I had an incredible time here. Dinner at Idol Wolf was fantastic — the food and service both hit the mark and set the tone for the evening. Afterward we wandered the hotel's art galleries with a complimentary night cap in hand, which felt like such a unique way to unwind. We capped off the night in the downstairs sauna before heading to bed, which was the perfect way to relax after a day of exploring. The gym was genuinely impressive too — well-equipped and clearly not an afterthought like at a lot of boutique hotels. Apparently the building used to be the YMCA. On top of all that, the staff was warm and attentive from check-in to check-out, and the overall amenities exceeded our expectations. This isn't just a place to sleep — it's an experience in itself. Highly recommend for anyone visiting St. Louis who wants a hotel with personality, great food, and a little bit of culture built right in. Would absolutely stay again!"

The West End

10/10 Excellent

"Room was clean, the kitchen and little treats left in the room were nice! Garage was safe parking, and I loved sitting on the patio in the shade reading my book. Everyone was so friendly! We went to 2 ballgames and were just 3 to 4 miles from busch stadium parking. I feel like there were several food options close and Walgreens across the street was nice to pick up items we forgot to bring! We will definitely stay here again. The only thing that was a pain was the neighbors next to room 204 were loud at midnight both nights but that is no fault of the hotel. I thought everyone might respect the 10-6 quiet time. I also liked that it didn't seem like a huge hotel and they had our names on the VIP sign at check in. That was so nice!"

Pear Tree Inn St. Louis Near Union Station

8/10 Good

"Hotel is a bit old and could use a refresher and deeper clean. Location was great, right next to soccer stadium, 30 min walk to the baseball stadium, and 20 min walk to city museum. Breakfast was good and it was nice to have snacks and drinks in the evening."

Frequently asked questions

What is Uptown like?

Travellers to the Uptown neighbourhood in Collinsville will be sure to enjoy their stay. Are you looking for Uptown travel tips? Make sure that you visit World's Largest Catsup Bottle and Kruta Bakery while you're in the neighbourhood.

If I need to cancel my hotel reservation in Uptown, will I receive a refund?

Yes! Most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer in Uptown.

What is there to do in this Collinsville neighbourhood?

A few attractions you might want to check out while you're in Uptown are World's Largest Catsup Bottle and Kruta Bakery. While you're out sightseeing, Gateway Conference Center and Gateway Fun Park are a couple of additional sights to visit in Collinsville.

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Our top choices for Uptown hotels

1. Americas Best Value Inn Collinsville St. Louis

2. Drury Inn & Suites St. Louis Collinsville

3. Days Inn by Wyndham Collinsville/St. Louis

4. Comfort Inn Collinsville near St. Louis

5. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

6. Super 8 by Wyndham Collinsville St. Louis

7. Hampton Inn Collinsville

8. Best Western Troy Hotel

9. Holiday Inn St. Louis Fairview Heights by IHG

10. Quality Inn O'Fallon - St. Louis - Shiloh

11. Holiday Inn Express Troy by IHG

12. Drury Inn & Suites St. Louis Fairview Heights

13. Red Roof Inn St Louis - Troy, IL

14. Comfort Suites Fairview Heights - St. Louis

15. Radisson Hotel Fairview Heights - St. Louis

16. Super 8 by Wyndham Troy IL/St. Louis Area

17. Fairfield Inn & Suites by Marriott O'Fallon, IL

18. Pear Tree Inn St. Louis Near Union Station

19. DoubleTree by Hilton Collinsville - St. Louis

20. Best Western Plus MidAmerica Hotel

Where to stay in Uptown

Eastport

Mulberry Hills

Historic Downtown Collinsville

Top Uptown Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Frequently asked questions