De Soto Hotel Guide - 4 Stars Hotels in De Soto, Missouri

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Check availability on De Soto 4 Star Hotels

Tonight
30 Jan - 31 Jan
Tomorrow
31 Jan - 1 Feb
This weekend
30 Jan - 1 Feb
Next weekend
6 Feb - 8 Feb
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Learn more about De Soto

Get away to De Soto! Enjoy the local cuisine and more.

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Kayaking down the Big River on a fall day!
Photo by Jessica King
Open Photo by Jessica King

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Frequently asked questions

How much does it cost to stay in a 4-star hotel in De Soto?
With Expedia's search and sort filters, locking in an awesome deal on a 4-star hotel in De Soto just got easier. Start by keying in your chosen arrival date and length of your trip. Then sort the results by price and pick the option that best fits your style and budget.

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What's the difference between 5-star and 4-star hotels in De Soto?
Treat yourself to refined living during your De Soto getaway by staying at a 4-star hotel. As well as featuring upmarket accommodation, these properties are usually filled with amenities, including complimentary bathrobes, large beds and more. A 5-star hotel will go above and beyond to make your trip an even more lavish and memorable one. 24-hour front desk, on-site spas and gourmet dining are a few of the superior conveniences and services you'll likely be able to enjoy.
Does De Soto have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to search for your next getaway in De Soto where just about everything is taken care of, from your meals to your accommodation, entertainment and activities. We can also help you find standard 4-star stays in and around this sought-after destination.