A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Defiance Hotel Guide - 4 Stars Hotels in Defiance, St. Louis

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Check availability on Defiance 4 Star Hotels

Next weekend
31 Jul - 2 Aug
In two weeks
7 Aug - 9 Aug

Our top choices for Defiance 4-star hotels

Outdoor pool, open 10:00 AM to 6:00 PM, pool cabanas (surcharge)

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,021 reviews)
"I love staying here!"
United States
Tracey
The price is Rp2.650.737
Rp3.395.817 total
includes taxes & fees
9 Aug - 10 Aug
Ameristar Casino Resort and Spa
Exterior

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,003 reviews)
"Loved this hotel. Beautiful property, with amazing architecture. Room was very clean and nice. Also, it is very close to, and easy to get to, all parts of STL. Definitely recommend staying here!"
United States
Kennedy
The price is Rp2.783.906
Rp3.242.916 total
includes taxes & fees
2 Aug - 3 Aug
Hilton St. Louis Frontenac
Indoor pool

DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport
4.0 star property
Westport
8.0 out of 10, Very good, (1,001 reviews)
"The staff was excellent, the room was clean and the bar was great."
United States
Presley
The price is Rp2.235.543
Rp2.592.962 total
includes taxes & fees
23 Aug - 24 Aug
DoubleTree by Hilton St. Louis - Westport
Reception

DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
4.0 star property
Chesterfield
8.8 out of 10, Excellent, (1,000 reviews)
"Loved the atmosphere & the room, just wish the pool didn’t close so early."
United States
Shon
The price is Rp2.788.689
Rp3.234.544 total
includes taxes & fees
16 Aug - 17 Aug
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Bar (on property)

The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
8.8 out of 10, Excellent, (159 reviews)
"Fantastic location for exploring Washington. Comfortable rooms and the bar and restaurant next door was something special."
Australia
Elaine
The price is Rp2.320.380
Rp2.641.973 total
includes taxes & fees
3 Aug - 4 Aug
The Inn at Elijah McLeans
Apartment (2 Bedrooms) | Interior

'the Ruebling House': Bright, Modern, & Renovated!

'the Ruebling House': Bright, Modern, & Renovated!
4.0 star property
Defiance
'the Ruebling House': Bright, Modern, & Renovated!
Lounge

Landing Apartments - Eureka

Landing Apartments - Eureka
4.0 star property
Eureka
Landing Apartments - Eureka
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Top Defiance Hotel Reviews

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

10/10 Excellent
"The staff was very friendly and welcoming"
Charlene 2-night trip
Posted 11 hours ago
Hilton St. Louis Frontenac

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Defiance?
To book a 4-star hotel in Defiance that fits your budget, take advantage of Expedia's sort and search filters. Browse the available options during your chosen dates and use our pricing filter to set your maximum rate. You can also list your results by the cheapest retreat first.

  • Search for the lowest price from Rp2.592.962

What's the difference between 5-star and 4-star hotels in Defiance?
Treat yourself to luxury during your Defiance escape by checking in to a 4-star hotel. As well as featuring upscale accommodation, these retreats are typically packed with amenities like complimentary bathrobes, large beds and plenty more. A 5-star hotel will go above and beyond to make your trip an even more indulgent and special one. 24-hour front desk, on-site spas and gourmet dining are a few of the exclusive conveniences and services you'll likely get access to.
Does Defiance have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next dream getaway in Defiance where just about everything is taken care of, from your meals to your room, entertainment and activities. We can also help you find standard 4-star stays in and around this leading destination.