Find hotels in Defiance, MO from Rp1.380.075
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13 Aug - 14 AugTomorrow
14 Aug - 15 AugThis weekend
14 Aug - 16 AugNext weekend
21 Aug - 23 AugOur top choices for Defiance hotels
1. The Wildwood Hotel
The Wildwood HotelWildwood
Hailey
Rp1.576.751
Rp1.836.726 total
includes taxes & fees
24 Aug - 25 Aug
2. Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHGO'Fallon
Sheria
Rp1.803.961
Rp2.127.781 total
includes taxes & fees
23 Aug - 24 Aug
3. Drury Plaza Hotel St. Louis Chesterfield
Drury Plaza Hotel St. Louis ChesterfieldChesterfield
Andrea T
Rp2.321.751
Rp2.692.952 total
includes taxes & fees
30 Aug - 31 Aug
4. Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
Josh
Rp1.461.209
Rp1.723.497 total
includes taxes & fees
3 Sept - 4 Sept
5. Hyatt Place St. Louis/Chesterfield
Hyatt Place St. Louis/ChesterfieldChesterfield
Taylor
Rp2.002.224
Rp2.322.340 total
includes taxes & fees
13 Sept - 14 Sept
6. Comfort Inn & Suites Chesterfield - St. Louis
Comfort Inn & Suites Chesterfield - St. LouisChesterfield
Jessica
Rp1.503.003
Rp1.811.453 total
includes taxes & fees
23 Aug - 24 Aug
7. Best Western Plus Washington Hotel
Best Western Plus Washington HotelWashington
Jimi
Rp2.304.069
Rp2.623.182 total
includes taxes & fees
16 Aug - 17 Aug
8. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by WyndhamFenton
LINDSAY
Rp1.685.185
Rp1.946.185 total
includes taxes & fees
17 Aug - 18 Aug
9. Staybridge Suites O'Fallon Chesterfield by IHG
Staybridge Suites O'Fallon Chesterfield by IHGO'Fallon
Norman
Rp2.037.978
Rp2.403.796 total
includes taxes & fees
7 Sept - 8 Sept
10. Quality Inn Near Six Flags St. Louis
Quality Inn Near Six Flags St. LouisPacific
Brent
Rp1.679.827
Rp1.922.981 total
includes taxes & fees
16 Aug - 17 Aug
11. WoodSpring Suites St Peters-OFallon
WoodSpring Suites St Peters-OFallonSt. Peters
Ellen
Rp1.543.323
Rp1.827.272 total
includes taxes & fees
16 Aug - 17 Aug
12. Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHGWentzville
Karen
Rp2.411.235
Rp2.873.077 total
includes taxes & fees
16 Aug - 17 Aug
13. Sonesta ES Suites St. Louis - Chesterfield
Sonesta ES Suites St. Louis - ChesterfieldChesterfield
Quantrell
Rp1.960.213
Rp2.273.613 total
includes taxes & fees
16 Aug - 17 Aug
14. Drury Inn & Suites Southwest St. Louis
Drury Inn & Suites Southwest St. LouisValley Park
Larry
Rp2.125.280
Rp2.486.322 total
includes taxes & fees
23 Aug - 24 Aug
15. Courtyard by Marriott St. Louis Chesterfield
Courtyard by Marriott St. Louis ChesterfieldChesterfield
Steven
Rp1.806.640
Rp2.102.260 total
includes taxes & fees
28 Aug - 29 Aug
16. Residence Inn by Marriott O'Fallon
Residence Inn by Marriott O'FallonO'Fallon
Gerald
Rp2.339.791
Rp2.759.783 total
includes taxes & fees
28 Aug - 29 Aug
17. Super 8 by Wyndham O'Fallon MO/St. Louis Area
Super 8 by Wyndham O'Fallon MO/St. Louis AreaO'Fallon
Shelly
Rp1.170.050
Rp1.380.075 total
includes taxes & fees
13 Sept - 14 Sept
18. TownePlace Suites by Marriott St. Louis Chesterfield
TownePlace Suites by Marriott St. Louis ChesterfieldChesterfield
Cindy
Rp2.286.208
Rp2.683.163 total
includes taxes & fees
28 Aug - 29 Aug
19. Hampton Inn & Suites St. Louis/Chesterfield
Hampton Inn & Suites St. Louis/ChesterfieldChesterfield
Karen E
Rp1.962.567
Rp2.283.702 total
includes taxes & fees
30 Aug - 31 Aug
20. Quality Inn Foristell
Quality Inn ForistellForistell
Chris
Rp1.494.966
Rp1.688.565 total
includes taxes & fees
19 Aug - 20 Aug
Stay near popular Defiance attractions
August A. Busch Memorial Conservation Area
8.6/10 (7 reviews)
This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
Photo by Pages of Travel
Chandler Hill Vineyards
7.8/10 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
Historic Daniel Boone Home and Heritage Center
9.6/10 (4 reviews)
Step into the limestone home where Daniel Boone's son Nathan crafted a frontier masterpiece with seven fireplaces. Explore the surrounding historic village for an authentic glimpse into 19th-century pioneer life.
Sugar Creek Winery
8.0/10 (1 review)
Sip award-winning Missouri wines at this hillside vineyard along the scenic Katy Trail. Relax on covered decks with your own picnic while enjoying live weekend music and panoramic countryside views.
Yellow Farmhouse Winery
This boutique winery in Defiance, Missouri was known for its distinctive unfiltered wines and relaxed atmosphere. Visitors could enjoy tastings with live music while picnicking on scenic grounds with vineyard views.
Matson Hill Park Trailhead
Wander through 475 acres of rugged forest terrain with challenging hiking paths and gravity-flow mountain bike trails. The historic 1830s Hays Home offers a glimpse into pioneer life amid the natural splendour.
Broemmelsiek Park
This 494-acre natural playground offers nine miles of trails through forests and around serene lakes. Attend a monthly stargazing event at the astronomy viewing area for a uniquely celestial park experience.
Hamburg Trail Trailhead
This moderate 6.9-mile loop winds through the scenic Weldon Spring Conservation Area, connecting to the Katy Trail State Park. Spot native wildlife while traversing diverse landscapes of shaded woodlands and open fields.
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.
See all hotels in Defiance
Top Defiance Hotel Reviews
Hollywood Casino & Hotel St. Louis
10/10 Excellent
"Check-in was very easy and the staff was very helpful."
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
10/10 Excellent
"Breakfast is excellent, especially if you are with kids. Clean room as always when i book there. Pool is clean and open late at night. You must visit..."
La Quinta Inn & Suites by Wyndham St. Louis Westport
8/10 Good
"My room was clean, the bed comfortable. I appreciated the quiet air conditioner I could adjust to my comfort."
Drury Plaza Hotel St. Louis Chesterfield
10/10 Excellent
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Days Inn and Suites by Wyndham St. Louis/Westport Plaza
10/10 Excellent
"There was plenty of parking, AC worked like a dream, the beds were super comfy, and the staff was so kind, patient, and helpful. The only thing we were sad about was the pool. It wasn't dirty, it just looked a little too green and we don't know why. We didn't ask or press the issue because honestly we were out of the hotel for most of the time we were there. It may have been perfectly fine. We saw someone else getting ready to get into it. We were going to be checking in really late and they accommodated us. We got down to breakfast late one day, and they patiently waited for us to finish. We stayed for two nights. We had one bedroom with two queen size beds and it did not feel like the four of us were on top of each other, there was so much space! Overall good experience!!"
Hampton Inn St. Charles St. Peters
10/10 Excellent
"The hotel is in excellent condition. It’s either new or newly remodeled. Bed was super comfortable and pillows awesome. The breakfast area offered a lot to choose from. I highly recommend this hotel at this location in St Charles MO and would definitely stay again. Hotel exit is right off the highway which was very convenient. We stayed in room 416 and it was very quiet!"
Sonesta ES Suites St. Louis - Chesterfield
8/10 Good
"Great place to stay. Room was comfortable and roomy. Definitely recommend staying here"
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
8/10 Good
"Missing shower curtain in one of the bathrooms , call the front desk multiple times was never able to get a hold of anybody, check out was 11. Our keys stopped working at nine difficult to load our cars when we kept getting locked out. .. hotel was very clean pool area very nice and clean front desk very helpful and nice."
Best Western Plus Fenton
8/10 Good
"Clean rooms, friendly staff, good breakfast, however workout room equipment was really dirty."
More cheap stays in Defiance
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
1970 Craig Rd Maryland Heights MO
Rp1.214.548
Rp1.408.730 total
25 Aug - 26 Aug
includes taxes & fees
4.4/10 (1,019 reviews)
Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive O'Fallon MO
Rp1.461.209
Rp1.723.497 total
3 Sept - 4 Sept
includes taxes & fees
9/10 Wonderful! (1,078 reviews)
Best Western Plus St. Louis West-Westport
12220 Dorsett Rd Maryland Heights MO
Rp1.654.822
Rp1.919.395 total
17 Aug - 18 Aug
includes taxes & fees
8/10 Very good! (1,105 reviews)
Hampton Inn St. Charles St. Peters
3720 W Clay St St. Charles MO
Rp1.742.876
Rp2.003.035 total
2 Sept - 3 Sept
includes taxes & fees
8/10 Very good! (1,000 reviews)
Best Western Plus Fenton
1680 Fenton Business Park Ct Fenton MO
Rp1.849.149
Rp2.135.544 total
16 Aug - 17 Aug
includes taxes & fees
9/10 Wonderful! (429 reviews)
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
11 Arnage Boulevard Chesterfield MO
Rp1.984.347
Rp2.309.046 total
13 Sept - 14 Sept
includes taxes & fees
9/10 Wonderful! (1,000 reviews)
