Top Motels in Cape Girardeau County in 2026

Upper Indian Creek Cape Girardeau County Missouri A rocky brook on the side of a country road. Evening sunlight brightens the top of the large rocks. Colorful trees in foliage along the bank.

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Our top choices for Cape Girardeau County motels

Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, individually decorated, individually furnished, desk

Super 8 by Wyndham Perryville

Perryville

Cynthia

Rp1.449.115 total

includes taxes & fees

20 Jul - 21 Jul

Town House Inn Cape Giradreau

Cape Girardeau

Rosealee

Rp1.572.166 total

includes taxes & fees

27 Jun - 28 Jun

Economy Single Room, 1 Queen Bed, Kitchenette | Private kitchen | Fridge, microwave, oven, stovetop

Town House Inn

Jackson

Jennifer

Rp1.538.741 total

includes taxes & fees

30 Jun - 1 Jul

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Top Cape Girardeau County Hotel Reviews

Town House Inn Cape Giradreau

10/10 Excellent

"We stayed here for the last two months due to our house had to be tore down. Excellent place for your pets if you have them. We had our 4 dogs so it worked the best. They were great and only a few things that we had to adjust for our liking. But for us if you have to use a place that is cheaper then the rest this is the place to be."

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"I was driving north to WI from South AL for work and needed a somewhat halfway stop, as a solo traveler I recommend this hotel. Easy to get to and felt safe at the hotel and the surrounding areas. I even walked over to Outback Steakhouse for dinner with no issues. Friendly and helpful front desk staff, clean and specious room (king bed). I’m considering booking this hotel again on my trip home back to AL."