
Search Hotels in Downtown South San Francisco, San Francisco
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Downtown South San Francisco hotels

Miller Apartments
Miller Apartments
Airport Inn
Airport Inn
La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hotel Mira Vista
Hotel Mira Vista
Comfort Inn Castro Valley
Comfort Inn Castro Valley
The Marina Inn on San Francisco Bay
The Marina Inn on San Francisco Bay
Pacifica Beach Hotel
Pacifica Beach Hotel
Inn at Rockaway San Francisco Pacifica
Inn at Rockaway San Francisco Pacifica
Menlo Park Inn
Menlo Park Inn
Half Moon Bay Lodge
Half Moon Bay Lodge
Aloft San Francisco Airport
Aloft San Francisco Airport
Hampton Inn Oakland Downtown-City Center
Hampton Inn Oakland Downtown-City Center
Hotel Nova SFO
Hotel Nova SFO
Executive Inn & Suites Embarcadero Cove
Executive Inn & Suites Embarcadero Cove
Stanyan Park Hotel
Stanyan Park Hotel
La Quinta Inn & Suites by Wyndham Oakland - Hayward
La Quinta Inn & Suites by Wyndham Oakland - Hayward
Hampton Inn & Suites San Mateo-San Francisco Airport
Hampton Inn & Suites San Mateo-San Francisco Airport
SFO El Rancho Inn SureStay Collection by Best Western
SFO El Rancho Inn SureStay Collection by Best Western
The Dylan at SFO
The Dylan at SFOWhere to stay in Downtown South San Francisco

Union Square
Fashion puts on its finest face in one of the country’s largest shopping plazas.

Fisherman's Wharf
This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

Downtown San Francisco
Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Warfield Theatre are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market
From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill
Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.
Top Downtown South San Francisco Hotel Reviews

























































































