Search Hotels in Glendale, Rochester

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
12 Dec - 13 Dec
Tomorrow
13 Dec - 14 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Glendale hotels

Terrace/patio
Hampton Inn Rochester-South

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
6.6 km from Glendale
9.0 out of 10, Wonderful, (1006)
"We had a wonderful stay!"
United States
Sarah
The price is Rp1.371.807
Rp1.579.294 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Rochester-South
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester, 3.9 km from Glendale
8.8 out of 10, Excellent, (884)
"Great room and stay!"
United States
Trevor
The price is Rp1.267.376
Rp1.459.150 total
includes taxes & fees
26 Dec - 27 Dec
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Exterior
Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
10.2 km from Glendale
8.8 out of 10, Excellent, (1000)
"Everything was great !"
United States
Kathryn
The price is Rp1.217.348
Rp1.401.471 total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express Rochester South - Mayo Area by IHG
Breakfast served
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester, 3.9 km from Glendale
8.8 out of 10, Excellent, (850)
"Everything was wonderful! Helpful, friendly staff, great location, nice amenities."
United States
kristi
The price is Rp1.784.832
Rp2.054.787 total
includes taxes & fees
20 Dec - 21 Dec
Hilton Garden Inn Rochester Downtown, MN
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
10.6 km from Glendale
7.2 out of 10, Good, (1020)
"Breakfast was good. The staff was great. "
United States
Kjirsta
The price is Rp1.188.165
Rp1.367.932 total
includes taxes & fees
13 Dec - 14 Dec
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Indoor pool, open 7:00 AM to 11:00 PM, pool loungers
AmericInn by Wyndham Rochester

AmericInn by Wyndham Rochester

AmericInn by Wyndham Rochester
2.0 star property
15.5 km from Glendale
8.8 out of 10, Excellent, (1003)
"Clean rooms, friendly staff, good stay"
United States
Della
The price is Rp1.261.539
Rp1.452.346 total
includes taxes & fees
17 Dec - 18 Dec
AmericInn by Wyndham Rochester
Serves lunch, dinner and happy hour
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
6.2 km from Glendale
8.2 out of 10, Very good, (1132)
"Great location and value"
United States
Michelle
The price is Rp1.217.014
Rp1.401.088 total
includes taxes & fees
26 Dec - 27 Dec
AmericInn by Wyndham Rochester Near Mayo Clinic
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 3.4 km from Glendale
9.2 out of 10, Wonderful, (1004)
"Great location. Friendly staff. Easy access to Mayo Clinic’s via shuttle. Rooms were comfortable and spacious. "
United States
Jill
The price is Rp2.151.204
Rp2.476.574 total
includes taxes & fees
20 Dec - 21 Dec
Hyatt House Rochester/Mayo Clinic Area
Free daily full breakfast
Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
6.7 km from Glendale
9.0 out of 10, Wonderful, (896)
"Good breakfast..shuttle service is excellent..super nice staff.."
United States
DALE K
The price is Rp1.052.422
Rp1.211.601 total
includes taxes & fees
2 Jan - 3 Jan 2026
Econo Lodge Mayo Clinic Area
Reception
America's Stay Inn Stewartville

America's Stay Inn Stewartville

America's Stay Inn Stewartville
2.5 star property
20.9 km from Glendale
8.0 out of 10, Very good, (419)
"Room was nicer and furnished better than most high end places I’ve stayed at. It’s a small hotel on a busy road, but comfortable bed and clean."
Canada
Robert
America's Stay Inn Stewartville
Exterior
Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
6 km from Glendale
9.2 out of 10, Wonderful, (1000)
"Everything in this Hampton was fabulous!! From the great room to the great breakfast to the coloring pages and crayons for our grandchildren to the desk person to the man who brought more towels, coffee to the room!!! We loved our stay!!!"
United States
Pamela
The price is Rp1.454.147
Rp1.674.087 total
includes taxes & fees
19 Dec - 20 Dec
Hampton Inn & Suites Rochester-North
Room, 2 Queen Beds | Desk, blackout curtains, iron/ironing board, free cots/infant beds
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester, 3.7 km from Glendale
8.0 out of 10, Very good, (1516)
"Clean Great breakfast, friendly staff "
United States
ilona
The price is Rp2.217.908
Rp2.553.429 total
includes taxes & fees
27 Dec - 28 Dec
Kahler Inn and Suites - Mayo Clinic Area
Front of property – evening/night
Kahler Grand Hotel

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester, 3.7 km from Glendale
8.4 out of 10, Very good, (1824)
"Staff was friendly and helpful! Will continue to stay here while at the Mayo, "
United States
Gayle
The price is Rp2.236.252
Rp2.574.608 total
includes taxes & fees
14 Dec - 15 Dec
Kahler Grand Hotel
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 4.4 km from Glendale
9.4 out of 10, Exceptional, (956)
"Rooms are comfortable and staff was was so professional and helpful."
United States
William
The price is Rp1.686.777
Rp1.975.254 total
includes taxes & fees
13 Dec - 14 Dec
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Indoor spa tub
Quality Inn near Medical Center

Quality Inn near Medical Center

Quality Inn near Medical Center
2.5 star property
6 km from Glendale
7.8 out of 10, Good, (808)
"Nice place to stay. Staff very helpful and kind"
United States
Stephen
The price is Rp978.047
Rp1.125.976 total
includes taxes & fees
19 Dec - 20 Dec
Quality Inn near Medical Center
Exterior
Spark by Hilton Rochester South

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
10.3 km from Glendale
9.4 out of 10, Exceptional, (310)
"Great place"
United States
Abidemi
The price is Rp1.147.309
Rp1.320.906 total
includes taxes & fees
4 Jan - 5 Jan 2026
Spark by Hilton Rochester South
Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency, Upgrade) | Premium bedding, desk, blackout curtains, iron/ironing board
Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center
2.5 star property
5.9 km from Glendale
9.0 out of 10, Wonderful, (580)
"Nice place to stay "
United States
Melissa
The price is Rp1.136.803
Rp1.308.745 total
includes taxes & fees
4 Jan - 5 Jan 2026
Sleep Inn & Suites West-Near Medical Center
Lobby
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester, 3.6 km from Glendale
9.6 out of 10, Exceptional, (543)
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is Rp2.857.933
Rp3.290.195 total
includes taxes & fees
19 Dec - 20 Dec
Hilton Rochester Mayo Clinic Area
Property amenity
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester, 4.1 km from Glendale
9.6 out of 10, Exceptional, (480)
"Overall great place"
United States
Jill
The price is Rp1.967.768
Rp2.265.393 total
includes taxes & fees
26 Dec - 27 Dec
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) | Blackout curtains, soundproofing, iron/ironing board, rollaway beds
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
6.6 km from Glendale
8.2 out of 10, Very good, (785)
"Great place to stay. Freindly staff"
United States
joel
The price is Rp1.489.334
Rp1.714.595 total
includes taxes & fees
2 Jan - 3 Jan 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Glendale

Find the best Glendale areas for the activities you enjoy most.
Rochester showing skyline and a city
Photo by Howard Lower Photography
Open Photo by Howard Lower Photography

Downtown Rochester

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Rochester which includes a river or creek and forests
Photo by Chad Johnson
Open Photo by Chad Johnson

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

Slatterly Park

While Slatterly Park isn't home to many top sights, Rochester Art Center and Soldiers Field Veterans Memorial are some notable places to visit nearby.

Northrup

When in Northrup, you can plan a visit to Rochester Civic Theater and Mayo Civic Center, some noteworthy sights in the nearby area.

Top Glendale Hotel Reviews

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent
"Quiet , clean easy access."
Gayla 2-night trip
Posted 1 day ago
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

10/10 Excellent
"I arrived late at night and the young man checking me in was most helpful and friendly (don't always see this at 11 pm!) Very clean and comfortable room, even including a selection of different thicknesses of pillows! (A bonus for those of us who don't like sleeping with our head a foot up in the air...) Excellent breakfast choices."
Sally 1-night trip
Posted 5 days ago
Med City Inn & Suites - Mayo Clinic Area

Explore a world of travel with Expedia

Frequently asked questions

What is Glendale like?
Travellers will be sure to enjoy their time in Rochester's Glendale neighbourhood.
If I need to cancel my hotel reservation in Glendale, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to view the top deals on offer in Glendale.
What is there to do around this Rochester neighbourhood?
National Volleyball Center, Rochester Recreation Center and Minnesota Children's Museum are just a few of the places to visit in and around Glendale. While you're out sightseeing, Quarry Hill Nature Center and Assisi Heights are a couple of additional sights to visit in Rochester.