Search Hotels in Isle of Palms, Jacksonville

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Our top choices for Isle of Palms hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (492 reviews)
"Location was very perfect for an appointment at The Mayo Clinic. Staff could not have been nicer."
United States
Jill
The price is Rp2.400.517
Rp2.724.586 total
includes taxes & fees
8 May - 9 May
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.9 km from Isle of Palms
8.8 out of 10, Excellent, (1,018 reviews)
"Great stay!"
United States
Satavia
The price is Rp1.649.435
Rp1.872.110 total
includes taxes & fees
3 May - 4 May
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
30.8 km from Isle of Palms
8.8 out of 10, Excellent, (384 reviews)
"Nice place to stay!"
United States
Terryl
The price is Rp1.403.233
Rp1.592.606 total
includes taxes & fees
3 May - 4 May
Extended Stay America Premier Suites - Jacksonville - Airport

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.4 km from Isle of Palms
9.2 out of 10, Wonderful, (319 reviews)
"Close to airport and nice modern facility."
United States
Cheryl
The price is Rp2.330.000
Rp2.644.549 total
includes taxes & fees
31 May - 1 Jun
Home2 Suites By Hilton Jacksonville Downtown

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.3 km from Isle of Palms
7.6 out of 10, Good, (461 reviews)
"The property was very clean and the staff was very nice. Breakfast was delicious "
United States
Jose
The price is Rp1.266.704
Rp1.437.709 total
includes taxes & fees
4 May - 5 May
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
2.1 km from Isle of Palms
9.4 out of 10, Exceptional, (215 reviews)
"It was a very nice hotel , would recommend for any one 👌 "
United States
Michael
The price is Rp2.930.693
Rp3.326.419 total
includes taxes & fees
15 May - 16 May
Hilton Jacksonville At Mayo Clinic

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,076 reviews)
"Great place to stay"
United States
Jeffrey
The price is Rp2.341.609
Rp2.657.808 total
includes taxes & fees
25 May - 26 May
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.7 km from Isle of Palms
8.8 out of 10, Excellent, (683 reviews)
"Rooms and the staff were very nice "
United States
Brant
The price is Rp3.035.255
Rp3.838.314 total
includes taxes & fees
12 May - 13 May
Seahorse Oceanfront Inn

Tru by Hilton Jacksonville Airport I-95

Tru by Hilton Jacksonville Airport I-95
2.5 star property
31.5 km from Isle of Palms
9.4 out of 10, Exceptional, (1,047 reviews)
"great stay"
United States
Teresa
The price is Rp1.562.112
Rp1.772.998 total
includes taxes & fees
11 May - 12 May
Tru by Hilton Jacksonville Airport I-95

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (3,887 reviews)
"We loved this stay- it was relaxed and fun!"
United States
Amy
The price is Rp2.947.153
Rp3.345.131 total
includes taxes & fees
3 May - 4 May
Margaritaville Jacksonville Beach

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
5 km from Isle of Palms
8.4 out of 10, Very good, (1,002 reviews)
"Great location and friendly staff. "
United States
Harry
The price is Rp3.153.332
Rp3.579.032 total
includes taxes & fees
11 May - 12 May
Courtyard by Marriott Jacksonville Beach Oceanfront

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.3 km from Isle of Palms
8.8 out of 10, Excellent, (1,001 reviews)
"Staff was incredibly friendly, breakfast was great, nice location."
United States
Melissa
The price is Rp1.853.882
Rp2.104.157 total
includes taxes & fees
4 May - 5 May
Holiday Inn Express Jacksonville - Blount Island by IHG

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,004 reviews)
"Very enjoyable stay!"
United States
Kristin
The price is Rp2.415.244
Rp2.692.997 total
includes taxes & fees
25 May - 26 May
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Wingate by Wyndham Jacksonville FL

Wingate by Wyndham Jacksonville FL
3.0 star property
15.4 km from Isle of Palms
7.4 out of 10, Good, (1,002 reviews)
"The staff at this hotel were very friendly and accommodating. The room was comfortable and very clean, though the curtain was short and allowed a lot of sunlight in at sunup."
United States
Josie
The price is Rp1.234.478
Rp1.401.133 total
includes taxes & fees
4 May - 5 May
Wingate by Wyndham Jacksonville FL

Weekly Inn

Weekly Inn
2.0 star property
14.9 km from Isle of Palms
7.6 out of 10, Good, (1,242 reviews)
"Thank you for the stay the room was clean and quiet and comfortable. Thanks for the stay"
United States
Bobbi
The price is Rp842.044
Rp955.721 total
includes taxes & fees
3 May - 4 May
Weekly Inn

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,004 reviews)
"Very convenient to the beach and short walk to restaurants. "
United States
Michelle
The price is Rp2.591.796
Rp2.941.688 total
includes taxes & fees
17 May - 18 May
Best Western Oceanfront

Hampton Inn & Suites Jacksonville South - Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
18.5 km from Isle of Palms
9.0 out of 10, Wonderful, (1,001 reviews)
"Clean room, friendly staff, great breakfast"
United States
Jared
The price is Rp1.767.252
Rp2.005.831 total
includes taxes & fees
31 May - 1 Jun
Hampton Inn & Suites Jacksonville South - Bartram Park

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
3 km from Isle of Palms
9.2 out of 10, Wonderful, (607 reviews)
"Always nice, clean amd convenient to Mayo Clinic."
United States
DARON or CHARLON
The price is Rp2.061.794
Rp2.340.137 total
includes taxes & fees
25 May - 26 May
TownePlace Suites by Marriott Jacksonville East

Home2 Suites by Hilton Jacksonville Airport

Home2 Suites by Hilton Jacksonville Airport
3.0 star property
31.3 km from Isle of Palms
8.8 out of 10, Excellent, (1,000 reviews)
"Clean room staff is super nice and breakfast was good "
United States
Shawntavia
The price is Rp1.752.525
Rp1.989.198 total
includes taxes & fees
4 May - 5 May
Home2 Suites by Hilton Jacksonville Airport

Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport
3.0 star property
31.1 km from Isle of Palms
9.0 out of 10, Wonderful, (2,477 reviews)
"Really nice place to stay"
United States
Kenneth
The price is Rp2.009.816
Rp2.281.141 total
includes taxes & fees
12 May - 13 May
Hyatt Place Jacksonville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms

Find the best Isle of Palms areas for the activities you enjoy most.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Top Isle of Palms Hotel Reviews

Frequently asked questions

What is Isle of Palms like?
Travellers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighbourhood.
What's a favourite hotel to stay in Isle of Palms?
Based on our traveller data, Residence Inn By Marriott Jacksonville - Mayo Clinic Area is one of the top choices for your stay in Isle of Palms. This hotel offers free breakfast and an outdoor pool.
How many hotels should I expect to find in Isle of Palms?
Expedia has 43 hotels and other accommodation options in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Isle of Palms.
What is there to do in this Jacksonville Beach neighbourhood?
A few places to visit in the area around Isle of Palms include Cradle Creek Preserve, Jacksonville Beach Golf Club and Windsor Parke Golf Club. While you're out sightseeing in Jacksonville Beach, make sure that you visit other sights such as Players by the Sea or Rhoda Martin Cultural Heritage Center.