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Our top choices for Isle of Palms hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (542 reviews)
"My family stayed here. Clean hotel and great breakfast."
United States
Ryan
The price is Rp2.759.620
Rp3.132.169 total
includes taxes & fees
19 Jul - 20 Jul
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
30.8 km from Isle of Palms
9.0 out of 10, Wonderful, (481 reviews)
"Excellent stay!"
United States
Amy
The price is Rp1.441.946
Rp1.636.544 total
includes taxes & fees
21 Jun - 22 Jun
Extended Stay America Premier Suites - Jacksonville - Airport

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
9.1 km from Isle of Palms
9.4 out of 10, Exceptional, (210 reviews)
"Loved our stay"
United States
Jaime
The price is Rp2.707.357
Rp3.072.849 total
includes taxes & fees
27 Jun - 28 Jun
AC Hotel Jacksonville St Johns Town Center

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.3 km from Isle of Palms
7.6 out of 10, Good, (525 reviews)
"The hotel was clean and staff was proficient."
United States
Maxine
The price is Rp1.300.404
Rp1.475.958 total
includes taxes & fees
22 Jun - 23 Jun
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
9.7 km from Isle of Palms
9.6 out of 10, Exceptional, (110 reviews)
"Great staff and breakfast!"
United States
Kandi
The price is Rp2.384.396
Rp2.706.289 total
includes taxes & fees
24 Jun - 25 Jun
TownePlace Suites by Marriott® Jacksonville Mayport

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (4,053 reviews)
"Great room and very convenient location"
United States
Lyndi
The price is Rp2.976.829
Rp3.378.665 total
includes taxes & fees
29 Jun - 30 Jun
Margaritaville Jacksonville Beach

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.4 km from Isle of Palms
9.2 out of 10, Wonderful, (354 reviews)
"really enjoyed my stay at the hotel"
United States
Stacy
The price is Rp2.175.293
Rp2.468.958 total
includes taxes & fees
2 Jul - 3 Jul
Home2 Suites By Hilton Jacksonville Downtown

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.6 km from Isle of Palms
8.8 out of 10, Excellent, (718 reviews)
"We liked the hotel, it was a nice experience. We all had a good time."
United States
Shannon
The price is Rp2.708.869
Rp3.478.490 total
includes taxes & fees
28 Jun - 29 Jun
Seahorse Oceanfront Inn

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.3 km from Isle of Palms
8.8 out of 10, Excellent, (1,002 reviews)
The price is Rp1.744.792
Rp1.980.339 total
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express Jacksonville - Blount Island by IHG

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
2.1 km from Isle of Palms
9.4 out of 10, Exceptional, (260 reviews)
"Great hotel and very convenient to Mayo."
United States
Margaret
The price is Rp2.903.625
Rp3.295.614 total
includes taxes & fees
3 Jul - 4 Jul
Hilton Jacksonville At Mayo Clinic

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,057 reviews)
"Location was very convenient"
United States
Thomas
The price is Rp2.264.669
Rp2.570.363 total
includes taxes & fees
22 Jun - 23 Jun
Hyatt Place Jacksonville / St. Johns Town Center

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
Oceanfront, 5 km from Isle of Palms
8.6 out of 10, Excellent, (1,003 reviews)
"Great location, great staff."
United States
Donna
The price is Rp3.614.212
Rp4.102.130 total
includes taxes & fees
7 Jul - 8 Jul
Courtyard by Marriott Jacksonville Beach Oceanfront

Hampton Inn Jacksonville East Regency Square

Hampton Inn Jacksonville East Regency Square
2.5 star property
13 km from Isle of Palms
8.8 out of 10, Excellent, (1,003 reviews)
"The highlight of our trip to Jacksonville was the hotel where we stayed. The hotel staff—always smiling, helpful, and exemplifying true hospitality—along with the cleanliness of the hotel and the quality of the delicious, varied breakfast, left a lasting impression on us."
United States
Mehmet
The price is Rp1.445.329
Rp1.640.448 total
includes taxes & fees
18 Jul - 19 Jul
Hampton Inn Jacksonville East Regency Square

Wingate by Wyndham Jacksonville FL

Wingate by Wyndham Jacksonville FL
3.0 star property
15.4 km from Isle of Palms
7.4 out of 10, Good, (1,002 reviews)
"Clean room great staff always were helpful nice breakfast excellent housekeepers"
United States
Steven
The price is Rp1.201.095
Rp1.363.243 total
includes taxes & fees
25 Jun - 26 Jun
Wingate by Wyndham Jacksonville FL

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.9 km from Isle of Palms
9.6 out of 10, Exceptional, (90 reviews)
"I really like this location and would definitely stay here again."
United States
Althia
The price is Rp2.404.859
Rp2.729.515 total
includes taxes & fees
3 Jul - 4 Jul
Hyatt Studios Jacksonville/St Johns Town Center

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,001 reviews)
"Very enjoyable stay!"
United States
Kristin
The price is Rp2.321.286
Rp2.588.234 total
includes taxes & fees
19 Jul - 20 Jul
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

San Marco Inn East

San Marco Inn East
3.0 star property
19.7 km from Isle of Palms
8.6 out of 10, Excellent, (1,414 reviews)
"Excellent stay"
United States
shawn
The price is Rp1.170.613
Rp1.328.891 total
includes taxes & fees
22 Jun - 23 Jun
San Marco Inn East

Wyndham Garden Jacksonville

Wyndham Garden Jacksonville
3.0 star property
15.5 km from Isle of Palms
8.0 out of 10, Very good, (1,915 reviews)
"I enjoyed the stay"
United States
Siddiq
The price is Rp1.474.171
Rp1.673.184 total
includes taxes & fees
1 Jul - 2 Jul
Wyndham Garden Jacksonville

Quality Inn Atlantic Beach - Mayo Clinic Jax Area

Quality Inn Atlantic Beach - Mayo Clinic Jax Area
2.5 star property
9 km from Isle of Palms
7.8 out of 10, Good, (1,002 reviews)
"The room was clean. For the price I would stay here again."
United States
Karyn
The price is Rp1.754.762
Rp1.991.654 total
includes taxes & fees
2 Jul - 3 Jul
Quality Inn Atlantic Beach - Mayo Clinic Jax Area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.9 km from Isle of Palms
9.0 out of 10, Wonderful, (1,001 reviews)
"Everyone was very nice and the rooms were clean."
United States
Camille
The price is Rp2.154.284
Rp2.445.111 total
includes taxes & fees
19 Jul - 20 Jul
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms

Find the best Isle of Palms areas for the activities you enjoy most.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

Oceanfront

While visiting Oceanfront, you might make a stop by sights like Oceanfront Park and Northeast Florida Beaches.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Top Isle of Palms Hotel Reviews

Frequently asked questions

What is Isle of Palms like?
Travellers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighbourhood.
What's a favourite hotel to stay in Isle of Palms?
Based on our traveller data, Residence Inn By Marriott Jacksonville - Mayo Clinic Area is one of the top choices for your stay in Isle of Palms. This hotel offers free breakfast and an outdoor pool.
How many hotels should I expect to find in Isle of Palms?
Expedia has 39 hotels and other accommodation options in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Isle of Palms.
What is there to do in this Jacksonville Beach neighbourhood?
A few places to visit in the area around Isle of Palms include Cradle Creek Preserve, Jacksonville Beach Golf Club and Windsor Parke Golf Club. While you're out sightseeing in Jacksonville Beach, make sure that you visit other sights such as Players by the Sea or Rhoda Martin Cultural Heritage Center.