Search Holiday Rentals in La Mesa

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
25 Dec - 26 Dec
Tomorrow
26 Dec - 27 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for La Mesa holiday rentals

Apartment, 1 Bedroom, Balcony | Property grounds
Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
Las Mañanitas
The price is Rp1.283.539
Rp1.609.361 total
includes taxes & fees
5 Jan - 6 Jan 2026
Swette Love 10 Minutes From the Airport Tocumen
50-inch LED TV with satellite channels
Arcadia Condo Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (168)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
The price is Rp1.388.142
Rp2.301.499 total
includes taxes & fees
26 Dec - 27 Dec
Arcadia Condo Suites
Apartment | 2 bedrooms
Relaxing 2BR Apt at Coco del mar

Relaxing 2BR Apt at Coco del mar

Relaxing 2BR Apt at Coco del mar
2.0 star property
San Francisco
The price is Rp4.207.253
Rp4.627.978 total
includes taxes & fees
13 Jan - 14 Jan 2026
Relaxing 2BR Apt at Coco del mar
Outdoor pool
Boutique Apartments Atlapa

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very good, (28)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa
Lobby sitting area
San Francisco by Wynwood House

San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (56)
"Clean and walkable location"
United States
Tamera
The price is Rp1.901.151
Rp2.510.391 total
includes taxes & fees
26 Dec - 27 Dec
San Francisco by Wynwood House
Living area
Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is Rp801.954
Rp3.356.387 total
includes taxes & fees
10 Jan - 11 Jan 2026
Living 73 Panamá by Boutique Apartments
Apartment, 3 Bedrooms, Accessible, Pool View | Children’s area
Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City
2.0 star property
José Domingo Espinar
The price is Rp1.208.502
Rp1.329.352 total
includes taxes & fees
5 Jan - 6 Jan 2026
Charming 3 Bedroom Apartment in San Miguelito, Panama City
Apartment | 2 bedrooms
Brand New 2BR apt w Gym and Pool

Brand New 2BR apt w Gym and Pool

Brand New 2BR apt w Gym and Pool
2.0 star property
San Francisco
The price is Rp4.207.253
Rp5.203.353 total
includes taxes & fees
9 Jan - 10 Jan 2026
Brand New 2BR apt w Gym and Pool
Apartment | 2 bedrooms
Comfortable 2BR City Apartment

Comfortable 2BR City Apartment

Comfortable 2BR City Apartment
2.0 star property
San Francisco
The price is Rp4.207.253
Rp4.627.978 total
includes taxes & fees
9 Jan - 10 Jan 2026
Comfortable 2BR City Apartment
Apartment | 2 bedrooms
Lovely 2BR Apt Close to Shops

Lovely 2BR Apt Close to Shops

Lovely 2BR Apt Close to Shops
2.0 star property
San Francisco
The price is Rp4.207.253
Rp4.627.978 total
includes taxes & fees
13 Jan - 14 Jan 2026
Lovely 2BR Apt Close to Shops
Apartment | 1 bedroom
Dovle 510 in Ciudad de Panam

Dovle 510 in Ciudad de Panam

Dovle 510 in Ciudad de Panam
2.0 star property
San Francisco
The price is Rp3.638.615
Rp4.002.476 total
includes taxes & fees
9 Jan - 10 Jan 2026
Dovle 510 in Ciudad de Panam
Apartment | 2 bedrooms
Stylish 2BR Apt Near the Park Omar

Stylish 2BR Apt Near the Park Omar

Stylish 2BR Apt Near the Park Omar
2.0 star property
San Francisco
The price is Rp3.411.373
Rp4.327.885 total
includes taxes & fees
9 Jan - 10 Jan 2026
Stylish 2BR Apt Near the Park Omar
Apartment | 2 bedrooms
Urban 2BR Apt in Central Area

Urban 2BR Apt in Central Area

Urban 2BR Apt in Central Area
2.0 star property
San Francisco
The price is Rp3.411.373
Rp3.752.510 total
includes taxes & fees
8 Jan - 9 Jan 2026
Urban 2BR Apt in Central Area
Apartment | 1 bedroom
Elegant Loft Pool Gym and Workspaces

Elegant Loft Pool Gym and Workspaces

Elegant Loft Pool Gym and Workspaces
2.0 star property
San Francisco
The price is Rp3.638.615
Rp4.577.851 total
includes taxes & fees
10 Jan - 11 Jan 2026
Elegant Loft Pool Gym and Workspaces
Apartment | 2 bedrooms
Cozy 2BR Close to Panama Old Town

Cozy 2BR Close to Panama Old Town

Cozy 2BR Close to Panama Old Town
2.0 star property
San Francisco
The price is Rp4.207.253
Rp5.107.457 total
includes taxes & fees
22 Jan - 23 Jan 2026
Cozy 2BR Close to Panama Old Town
Apartment | 2 bedrooms
Spacious 2BR w Terrace Lounge

Spacious 2BR w Terrace Lounge

Spacious 2BR w Terrace Lounge
2.0 star property
San Francisco
The price is Rp3.411.373
Rp4.807.364 total
includes taxes & fees
13 Jan - 14 Jan 2026
Spacious 2BR w Terrace Lounge
Apartment | 1 bedroom
Two-level Apt by Panama old Town

Two-level Apt by Panama old Town

Two-level Apt by Panama old Town
2.0 star property
San Francisco
The price is Rp2.956.584
Rp3.731.721 total
includes taxes & fees
13 Jan - 14 Jan 2026
Two-level Apt by Panama old Town
Apartment | 1 bedroom
Dovle 509 in Ciudad de Panam

Dovle 509 in Ciudad de Panam

Dovle 509 in Ciudad de Panam
2.0 star property
San Francisco
The price is Rp3.638.615
Rp4.002.476 total
includes taxes & fees
9 Jan - 10 Jan 2026
Dovle 509 in Ciudad de Panam
Apartment | 1 bedroom
Smart Loft-style 1BR Apt Near to Shops

Smart Loft-style 1BR Apt Near to Shops

Smart Loft-style 1BR Apt Near to Shops
2.0 star property
San Francisco
The price is Rp3.638.615
Rp4.002.476 total
includes taxes & fees
9 Jan - 10 Jan 2026
Smart Loft-style 1BR Apt Near to Shops
Apartment | 1 bedroom
4 Guests 1 Bedroom Shared Pool

4 Guests 1 Bedroom Shared Pool

4 Guests 1 Bedroom Shared Pool
2.0 star property
San Francisco
The price is Rp3.638.615
Rp4.002.476 total
includes taxes & fees
11 Jan - 12 Jan 2026
4 Guests 1 Bedroom Shared Pool
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top La Mesa Hotel Reviews

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

10/10 Excellent
"Great breakfast was included and the airport shuttle was conveniently located "
Adrienne 1-night trip
Posted 2 days ago
Crowne Plaza Panama Airport by IHG

Find out more about La Mesa

Search for holiday rentals in La Mesa on Expedia.co.id! You can easily find your home rentals, villas, holiday apartments in La Mesa using one of the methods below:

  • View our selection of featured holiday rentals in La Mesa
  • Use the map to find apartments and other holiday homes in the La Mesa neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in La Mesa while they last

Look no further and take a look at our great range of rental properties in La Mesa!

Frequently asked questions

Are there holiday rentals in La Mesa?

Yes, there are holiday rentals close to the most popular sights in La Mesa, or you can select a more secluded option if you're looking for a relaxing stay.

What’s there to see and do in La Mesa?

While exploring the area, visit family-friendly sights like Chepo Youth Recreation Center, or get outside and enjoy nature at Chagres National Park. In the wider area, you’ll find Metromall Panama and Los Pueblos Commercial Center.

What’s a holiday rental in La Mesa like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in La Mesa. Holiday rentals provide amenities like laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you to travel. You'll also find more space in a holiday rental than in a hotel, which is another reason why a holiday rental is a great option for families.