Find hotels in La Mesa from Rp885.192

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for La Mesa hotels

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.5 star property
Tocumen
9.0 out of 10, Wonderful, (39)
Embrace comfort in this boutique hotel with complimentary airport transfers, WiFi, and parking. Located minutes from Metromall Panama, Multiplaza Pacific Mall, and Cinta Costera, it's an ideal base for exploring nearby commercial centers.

"It was a cool unique antique place that had modern touches. The staff was very friendly and helpful. Will definitely stay again. "
United States
Clarissa
The price is Rp2.011.800
Rp2.212.980 total
includes taxes & fees
18 Jan - 19 Jan 2026
ORHO HOTEL BOUTIQUE PANAMA Airport

Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
Las Mañanitas
The price is Rp1.283.539
Rp1.609.361 total
includes taxes & fees
5 Jan - 6 Jan 2026
Swette Love 10 Minutes From the Airport Tocumen

B&B Lodgings

B&B Lodgings
2.5 star property
24 de Diciembre
7.8 out of 10, Good, (73)
Stay in this welcoming hostal with pool and garden in 24 de Diciembre. After a refreshing swim, unwind with drinks from the bar. Each room provides conveniences like refrigerators and microwaves, plus free WiFi and parking.

"Friendly place. Owner cares and it shows. Everything was clean and new."
Mexico
Michael
The price is Rp804.720
Rp885.192 total
includes taxes & fees
26 Dec - 27 Dec
B&B Lodgings

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (644)
Unwind at this premium Panama City retreat featuring an 18-hole golf course and rejuvenating spa treatments. Just minutes from Multiplaza Pacific Mall, guests enjoy 2 restaurants serving local cuisine, a refreshing outdoor pool, and attentive service.

"As usual the stay was amazing in this hotel"
United States
Jose
The price is Rp3.759.551
Rp4.135.507 total
includes taxes & fees
25 Jan - 26 Jan 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1002)
Located in San Miguelito, this hotel offers easy access to Multiplaza Pacific Mall and Metromall Panama. Enjoy international cuisine at Centro restaurant, take a refreshing swim, or work out at the fitness centre. Guests praise the exceptional staff.

"The hotel is conveniently close to the airport and shopping centres. "
United States
Samantha
The price is Rp1.838.282
Rp2.022.110 total
includes taxes & fees
8 Jan - 9 Jan 2026
Courtyard by Marriott Panama Metromall

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (167)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
The price is Rp1.388.142
Rp2.301.499 total
includes taxes & fees
1 Jan - 2 Jan 2026
Arcadia Condo Suites

Brand New 2BR apt w Gym and Pool

Brand New 2BR apt w Gym and Pool
2.0 star property
San Francisco
The price is Rp4.212.774
Rp5.210.180 total
includes taxes & fees
8 Jan - 9 Jan 2026
Brand New 2BR apt w Gym and Pool

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1847)
Escape at this Tocumen resort where lush gardens create a peaceful retreat. Just minutes from PTY airport with free shuttle service, guests enjoy 2 tennis courts, casino, and La Veranda restaurant. The serene pool area offers a calm setting after exploring nearby Metromall.

"Better than expected: Location, transportation to and from airport, pool area tropical and comfortable. "
United States
Marty
The price is Rp2.096.471
Rp2.306.118 total
includes taxes & fees
26 Dec - 27 Dec
Riande Aeropuerto Hotel & Casino

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very good, (28)
Escape to these modern apartments with full kitchens and Smart TVs, just minutes from Multiplaza Pacific Mall. Take a refreshing dip in the outdoor pool after exploring nearby attractions, with free WiFi and parking making your Panama stay effortless.

"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.0 star property
San Francisco
The price is Rp3.244.027
Rp3.568.430 total
includes taxes & fees
27 Dec - 28 Dec
Dovle Residences by HMS-Preferred Member

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (311)
Luxurious sanctuary in Panama City with an outdoor pool and rejuvenating spa treatments. Costa Nova restaurant serves meals throughout the day, while the 24-hour fitness centre keeps your routine intact. Minutes from Multiplaza Pacific Mall and Avenida Balboa.

"Great hotel and services"
United States
Pedro
The price is Rp3.590.057
Rp3.949.063 total
includes taxes & fees
10 Jan - 11 Jan 2026
The Westin Panama

Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City
2.0 star property
José Domingo Espinar
Experience urban convenience in San Miguelito with easy access to Albrook and Multiplaza Pacific Malls. This apartment offers free parking and an outdoor pool, with Avenida Balboa and Cinta Costera just a short drive away.
The price is Rp1.208.502
Rp1.329.352 total
includes taxes & fees
8 Jan - 9 Jan 2026
Charming 3 Bedroom Apartment in San Miguelito, Panama City

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
Tocumen
8.4 out of 10, Very good, (2332)
Set mere steps from Tocumen Intl. Airport, this hotel offers an outdoor pool and The Gate Restaurant serving international cuisine. Travellers appreciate the helpful staff, convenient location, and free airport shuttle available round-the-clock. Metromall Panama is nearby.

"Great breakfast was included and the airport shuttle was conveniently located "
United States
Adrienne
The price is Rp1.844.150
Rp2.028.565 total
includes taxes & fees
15 Jan - 16 Jan 2026
Crowne Plaza Panama Airport by IHG

San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (56)
Centrally located near Multiplaza Pacific Mall and Cinta Costera, these modern apartments offer fully equipped kitchens and Smart TVs. Enjoy free WiFi while exploring nearby attractions including Albrook Shopping Mall, with convenient valet parking available.

"Clean and walkable location"
United States
Tamera
The price is Rp1.903.646
Rp2.513.686 total
includes taxes & fees
26 Dec - 27 Dec
San Francisco by Wynwood House

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (996)
Enjoy Panama City from this Art Deco resort offering an outdoor pool, 3 restaurants, and 2 bars. The Sheraton Grand sits minutes from Multiplaza Pacific Mall with free WiFi and parking. Guests praise the helpful staff and excellent condition of this spa-focused property.

"Was amazing food was delicious and stay was great "
United States
Amanda
The price is Rp2.248.187
Rp2.473.006 total
includes taxes & fees
9 Jan - 10 Jan 2026
Sheraton Grand Panama

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is Rp803.006
Rp3.360.791 total
includes taxes & fees
10 Jan - 11 Jan 2026
Living 73 Panamá by Boutique Apartments

Stylish 2BR Apt Near the Park Omar

Stylish 2BR Apt Near the Park Omar
2.0 star property
San Francisco
The price is Rp3.415.849
Rp4.333.563 total
includes taxes & fees
8 Jan - 9 Jan 2026
Stylish 2BR Apt Near the Park Omar

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1125)
Experience international cuisine at Fontanella restaurant and take a dip in the outdoor pool at this Panama City hotel. Just 5 minutes from Multiplaza Pacific Mall and Avenida Balboa, guests love the helpful staff and complimentary breakfast.

"The hotel is in a great location in Panama. Great amenities excellent breakfast."
United States
Maria
The price is Rp1.642.970
Rp1.807.267 total
includes taxes & fees
5 Jan - 6 Jan 2026
Ramada Plaza by Wyndham Panama Punta Pacifica

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (896)
Minutes from Albrook Shopping Mall, this urban retreat offers a refreshing poolside bar and nightclub for evening entertainment. Travellers love the convenient location, helpful staff, and 24-hour fitness centre, plus free parking and WiFi.

"Great staff..warm and welcoming...enjoyed our stay!"
United States
Alystra Marissa Arjoon
The price is Rp1.991.682
Rp2.190.850 total
includes taxes & fees
3 Jan - 4 Jan 2026
Aloft Panama

Comfortable 2BR City Apartment

Comfortable 2BR City Apartment
2.0 star property
San Francisco
The price is Rp4.207.253
Rp4.627.978 total
includes taxes & fees
9 Jan - 10 Jan 2026
Comfortable 2BR City Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top La Mesa Hotel Reviews

More cheap stays in La Mesa

Frequently asked questions

Where is the best place to stay in La Mesa?
Crowne Plaza Panama Airport by IHG, located 9.9 mi (15.9 km) from the heart of La Mesa, is a top choice for your stay, based on our traveller data. Two other choices for your trip to the area are Sheraton Grand Panama and Arcadia Condo Suites. See all available top hotels, or vacation rentals in La Mesa.
If I need to cancel my hotel reservation in La Mesa, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.
What is staying in La Mesa like?
Visitors to La Mesa will definitely find plenty to explore and enjoy. There are 444 hotels and other accommodation options in the surrounding area. Find out more about La Mesa.
What are the top places to visit in La Mesa?
Places to visit in the wider area include Metromall Panama, Los Pueblos Commercial Center and Estadio Rommel Fernandez. You'll also find Chagres National Park and Atrio Mall in the area. Take a look at what more there is to see and do in Expedia's La Mesa guide.
What's the seasonal weather like in La Mesa?
The hottest months are usually April and March, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in La Mesa are July, August, October and June, with each month seeing an average of 354 mm of rainfall.