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Tonight
15 Sept - 16 Sept
Tomorrow
16 Sept - 17 Sept
This weekend
18 Sept - 20 Sept
Next weekend
25 Sept - 27 Sept

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Our top choices for Lake Issaqueena hotels

A golf course with a water body, trees, and a distant view of a bridge.
A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.
A golf course with a clubhouse, surrounded by dense trees and a large body of water.
An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.

1. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
8.7 km from Lake Issaqueena
United States
Jennifer
Rp1.968.029
Rp2.184.645 total
includes taxes & fees
14 Oct - 15 Oct
Clemson University's James F. Martin Inn
An outdoor patio area with a fire pit, seating, and string lights.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A food court with a beverage display, seating area, and a Clemson University sign.

2. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
5.8 km from Lake Issaqueena
United States
Curtis
Rp1.949.538
Rp2.144.492 total
includes taxes & fees
27 Sept - 28 Sept
Tru by Hilton Seneca Clemson
A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.
A brick building with a sign reading "The Inn at Patrick Square".
A hotel with a brick facade, multiple windows, and a sign reading "The Inn at Patrick Square".
A hotel lobby with a long corridor, seating areas, and a reception desk.

3. The Inn at Patrick Square

The Inn at Patrick Square
9.2 km from Lake Issaqueena
United States
Christy
Rp2.624.039
Rp2.912.683 total
includes taxes & fees
27 Sept - 28 Sept
The Inn at Patrick Square
A white, two-story house with a front porch, surrounded by trees and shrubs.
A bedroom with two beds, a TV, and a fireplace.
A dining area with round tables, black chairs, and white tablecloths.
A two-story building with a white exterior, a front door, and a balcony.

4. Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
13 km from Lake Issaqueena
United States
enrique
Rp2.015.856
Rp2.237.425 total
includes taxes & fees
15 Oct - 16 Oct
Liberty Hall Bed and Breakfast
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.
A bar area with a counter, multiple chairs, and a display of bottles and glasses.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.

5. The Abernathy of Clemson

The Abernathy of Clemson
6.7 km from Lake Issaqueena
United States
Robert
Rp2.846.476
Rp3.159.571 total
includes taxes & fees
5 Oct - 6 Oct
The Abernathy of Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A spacious dining area with a long wooden table and patterned upholstered chairs.

6. Lakeside Lodge Clemson

Lakeside Lodge Clemson
5.6 km from Lake Issaqueena
United States
Christopher
Rp1.919.599
Rp2.382.944 total
includes taxes & fees
16 Sept - 17 Sept
Lakeside Lodge Clemson
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

7. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
6.7 km from Lake Issaqueena
United States
Laurrie
Rp4.209.029
Rp4.672.022 total
includes taxes & fees
27 Sept - 28 Sept
The Shepherd Hotel Downtown Clemson
A modern kitchen area with a bar counter and seating.
A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.
A modern living room with a grey sofa, purple and orange cushions, a coffee table with magazines, and a large window with patterned curtains.
A vending area with snacks and beverages, including chips and soda.

8. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
5.5 km from Lake Issaqueena
United States
Blaise
Rp1.862.892
Rp2.067.811 total
includes taxes & fees
27 Sept - 28 Sept
Hampton Inn Clemson-University Area
A poolside area with outdoor seating and a view of a lake and forested hills.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

9. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
10.6 km from Lake Issaqueena
United States
Angela
Rp2.112.792
Rp2.324.072 total
includes taxes & fees
27 Sept - 28 Sept
Fairfield Inn & Suites Seneca Clemson Univ Area
A modern bar area with a menu board, bar stools, and a countertop with various items.
A modern dining area with a bar, bar stools, and a patterned rug.
An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.
A Courtyard Marriott hotel with a brick facade, multiple floors, and a covered entrance area.

10. Courtyard Marriott Clemson

Courtyard Marriott Clemson
7.3 km from Lake Issaqueena
United States
Lee
Rp2.766.965
Rp3.071.331 total
includes taxes & fees
29 Sept - 30 Sept
Courtyard Marriott Clemson
A cabin with a large window, surrounded by trees.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A wooden interior with a table, chair, and a hanging lantern.
A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.

11. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
15.8 km from Lake Issaqueena
United States
Nirumol
Rp1.631.659
Rp2.569.709 total
includes taxes & fees
22 Sept - 23 Sept
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A hotel hallway with a carpeted floor, light-colored walls, and doors on both sides.
A hotel room with a bed, a sofa, a small round table, a lamp, and artwork on the wall.
A swimming pool with lounge chairs and a no diving sign.
A Comfort Inn & Suites hotel with a modern design, featuring a prominent sign and a well-maintained outdoor area with landscaping.

12. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
6.6 km from Lake Issaqueena
United States
Bradley
Rp1.862.313
Rp2.067.169 total
includes taxes & fees
8 Oct - 9 Oct
Comfort Inn & Suites Clemson - University Area
A modern office space with a desk, computer, and patterned chairs.
A hotel room with a large bed, a desk, a chair, a mirror, and a framed picture on the wall.
A conference room with a large round table, multiple chairs, and a projector.
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

13. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
7.1 km from Lake Issaqueena
United States
Jonathan
Rp2.271.819
Rp2.521.719 total
includes taxes & fees
22 Sept - 23 Sept
Holiday Inn Express & Suites Clemson by IHG
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.
A lobby with seating areas, a reception desk, and a patterned wall.
A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.
A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.

14. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
6.8 km from Lake Issaqueena
United States
David
Rp1.781.353
Rp1.977.303 total
includes taxes & fees
22 Sept - 23 Sept
Best Western Plus Clemson Hotel & Conference Center
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.
A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.
A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.
A wall with a decorative design featuring a building, trees, and a sky with clouds.

15. Inn @ Clemson

Inn @ Clemson
6.5 km from Lake Issaqueena
United States
Terry
Rp1.574.308
Rp1.747.464 total
includes taxes & fees
16 Sept - 17 Sept
Inn @ Clemson
A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.
A bedroom with a bed, bedside tables, a nightstand, a wooden floor, a door, and a wall-mounted shelf.
A cozy living room with a dining table, sofas, and a chandelier.
A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".

16. Clemson Memorabilia House

Clemson Memorabilia House
9.3 km from Lake Issaqueena
United States
Ashley
Rp1.567.379
Rp4.183.320 total
includes taxes & fees
22 Sept - 23 Sept
Clemson Memorabilia House
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

17. Best Western Seneca-Clemson

Best Western Seneca-Clemson
9.7 km from Lake Issaqueena
United States
Michelle
Rp1.712.303
Rp1.883.534 total
includes taxes & fees
21 Sept - 22 Sept
Best Western Seneca-Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A reception area with a counter, chairs, and a patterned rug.

18. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
8.6 km from Lake Issaqueena
United States
kendra
Rp2.107.332
Rp2.318.065 total
includes taxes & fees
27 Sept - 28 Sept
Hampton Inn & Suites Seneca-Clemson Area
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

19. Quality Inn Seneca US-123

Quality Inn Seneca US-123
13.5 km from Lake Issaqueena
United States
Steve
Rp1.331.392
Rp1.570.512 total
includes taxes & fees
24 Sept - 25 Sept
Quality Inn Seneca US-123
A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.
A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.
A gazebo with a tiled roof and a surrounding gravel area.
A reception desk with a vase of flowers, framed pictures, and a printer.

20. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
7.1 km from Lake Issaqueena
United States
David
Rp1.489.010
Rp1.652.800 total
includes taxes & fees
22 Sept - 23 Sept
Days Inn by Wyndham Clemson
View all properties

Compare popular hotels close to Lake Issaqueena

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A golf course with a water body, trees, and a distant view of a bridge.
Clemson University's James F. Martin Inn
9.4
Exceptional
1,001 reviews
View
An outdoor patio area with a fire pit, seating, and string lights.
Tru by Hilton Seneca Clemson
9.2
Wonderful
891 reviews
View
A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.
The Inn at Patrick Square
9.8
Exceptional
917 reviews
View
A white, two-story house with a front porch, surrounded by trees and shrubs.
Liberty Hall Bed and Breakfast
10.0
Exceptional
98 reviews
View
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
The Abernathy of Clemson
9.6
Exceptional
646 reviews
View

Top Lake Issaqueena Hotel Reviews

Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG

10/10 Excellent
"Really enjoyed our stay. Staff was friendly and very helpful."
Angela 2-night trip
Posted 16 hours ago
Holiday Inn Express & Suites Clemson by IHG
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

8/10 Good
"Great location & friendly staff. Room was clean. The hotel is a tad dated and worn , no doubt b/c it’s a popular place to stay but overall very pleasant"
Anne 2-night trip
Posted 17 hours ago
Best Western Plus Clemson Hotel & Conference Center
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent
"Friendly and convenient hotel that I keep returning to every year for business travel."
John 1-night trip
Posted 17 hours ago
Hampton Inn & Suites Seneca-Clemson Area
Courtyard Marriott Clemson

Courtyard Marriott Clemson

10/10 Excellent
"Nice environment and the people was outstanding"
Carey 1-night trip
Posted 21 hours ago
Courtyard Marriott Clemson
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

10/10 Excellent
"Always Stay Here When I'm In Clemson! Great Rates Great Staff!!"
Bradley 2-night trip
Posted 21 hours ago
Comfort Inn & Suites Clemson - University Area
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"Love this hotel!"
KAIJA 1-night trip
Posted 22 hours ago
The Shepherd Hotel Downtown Clemson
Inn @ Clemson

Inn @ Clemson

8/10 Good
"Super friendly staff! Only complaint was the mattress and the pillows. They certainly need an upgrade!"
Tonya Lynn 1-night trip
Posted 2 days ago
Inn @ Clemson
Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area

8/10 Good
"The hotel rooms need updating, but the hotel is clean, the breakfast is good, and the staff is very friendly."
Rebecca 2-night trip
Posted 1 month ago
Hampton Inn Clemson-University Area

Other attractions near Lake Issaqueena

Larry W. Abernathy Waterfront Park

8.6/10 (58 reviews)
Larry W. Abernathy Waterfront Park is just one of the places to see in Clemson, so why not enjoy the other things to explore during your travels? Experience the area's theatre scene or attend a football match.
See properties

Littlejohn Coliseum

9.4/10 (141 reviews)
Catch an event at Littlejohn Coliseum during your trip to Clemson. Amble around the area's lakeside or attend a football match.
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Sloan Tennis Center

Catch an event at Sloan Tennis Center during your trip to Clemson. You can attend a football match while in the area.
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Memorial Stadium

9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.
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Clemson Area African American Museum

You can spend time exploring the galleries in Clemson Area African American Museum in Clemson. You can attend a football match while in the area.
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Wyndham Plaza

You can search for that perfect souvenir at Wyndham Plaza during your stay in Seneca. Stroll along the lakeside or attend a sporting event in this family-friendly area.
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World of Energy

You can spend an afternoon browsing the exhibits at World of Energy in Seneca. Amble around this family-friendly area's lakeside or attend a sporting event.
See properties

Frequently asked questions

What's the area like around Lake Issaqueena?
Lake Issaqueena is located in Central. You'll find 208 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay near Lake Issaqueena?
Best Western Plus Clemson Hotel & Conference Center is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located 4.2 mi (6.8 km) from Lake Issaqueena. Other good choices within 5 miles include Lakeside Lodge Clemson and Comfort Inn & Suites Clemson - University Area.
How many hotels will I find close to Lake Issaqueena?
Expedia has 208 hotels and other accommodation options a few miles from Lake Issaqueena.
If I need to cancel the hotel reservation for my stay near Lake Issaqueena, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the top deals on offer near Lake Issaqueena.
What can I see and do near Lake Issaqueena?
You'll want to browse the exhibits at Fort Hill and Clemson Area African American Museum. Explore nature at Keowee Reservoir and Larry W. Abernathy Waterfront Park. If you've got some time to explore the area around Lake Issaqueena, you may want to make a stop by Littlejohn Coliseum, Memorial Stadium and Sloan Tennis Center.