Search Hotels Near Main Street Hyannis, Hyannis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
11 Mar - 12 Mar
Tomorrow
12 Mar - 13 Mar
This weekend
13 Mar - 15 Mar
Next weekend
20 Mar - 22 Mar

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Main Street Hyannis hotels

Interior entrance

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1,003 reviews)
"Very nice stay"
United States
Robert
The price is Rp1.992.363
Rp2.762.710 total
includes taxes & fees
12 Mar - 13 Mar
Anchor In Distinctive Waterfront Lodging
Dining

Sea Street Inn

Sea Street Inn
4.0 star property
1.5 km from Main Street Hyannis
9.8 out of 10, Exceptional, (45 reviews)
"Very nicely renovated small property with a fantastic breakfast."
United States
Paul
The price is Rp4.190.640
Rp4.796.228 total
includes taxes & fees
14 Mar - 15 Mar
Sea Street Inn
Indoor pool, seasonal outdoor pool

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
1.9 km from Main Street Hyannis
9.2 out of 10, Wonderful, (116 reviews)
"Clean, nice staff, good amenities, central location"
United States
Malbis
The price is Rp1.984.775
Rp2.350.965 total
includes taxes & fees
12 Mar - 13 Mar
Uncommoner Hotel by Reverie Boutique Collection
Indoor pool, seasonal outdoor pool

The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts
3.0 star property
2.1 km from Main Street Hyannis
9.2 out of 10, Wonderful, (254 reviews)
"Was unaware that pool facilities were closed for 2 weeks of maintenance which was primary purpose of stay"
United States
Edward
The price is Rp2.172.544
Rp2.486.477 total
includes taxes & fees
12 Mar - 13 Mar
The Cove at Yarmouth by Westgate Resorts
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,001 reviews)
"They were excellent. Felt extremely comfortable. Their breakfast was amazing, staff were so friendly!"
United States
Linda
The price is Rp2.011.507
Rp2.302.170 total
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn & Suites Cape Cod-West Yarmouth
Indoor pool

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (494 reviews)
"Parking was free and easy, room was very clean and housekeeping service was top notch. "
United States
Maureen
The price is Rp2.307.776
Rp2.641.250 total
includes taxes & fees
26 Mar - 27 Mar
Courtyard By Marriott Cape Cod Hyannis
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,553 reviews)
"The place was clean, staff very nice and a good breakfast! Nice pool and beach area."
United States
LisaAnn
The price is Rp1.576.690
Rp1.997.603 total
includes taxes & fees
12 Mar - 13 Mar
Bayside Resort Hotel
Lobby

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (682 reviews)
"Excellent staff-clean rooms-great location"
United States
Patrice
The price is Rp2.186.421
Rp2.502.350 total
includes taxes & fees
2 Apr - 3 Apr
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
Reception

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
0.3 km from Main Street Hyannis
8.4 out of 10, Very good, (20 reviews)
"It was ok staff was nice"
United States
Troy
The price is Rp2.002.524
Rp2.291.888 total
includes taxes & fees
29 Mar - 30 Mar
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Exterior

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
0.9 km from Main Street Hyannis
8.4 out of 10, Very good, (894 reviews)
"It was a decent stay I can’t complain "
United States
Rony
The price is Rp2.152.225
Rp2.463.222 total
includes taxes & fees
11 Apr - 12 Apr
Doubletree by Hilton Cape Cod - Hyannis
Indoor pool

Courtyard Resort

Courtyard Resort
2.0 star property
0.3 km from Main Street Hyannis
8.2 out of 10, Very good, (64 reviews)
"Great stay staff was awesome. The room was clean and reasonably priced!"
United States
Michael
The price is Rp1.838.067
Rp2.103.667 total
includes taxes & fees
12 Mar - 13 Mar
Courtyard Resort
Free daily continental breakfast

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (1,000 reviews)
"Nice hotel had a perfect stay"
United States
David
The price is Rp1.654.260
Rp1.893.300 total
includes taxes & fees
18 Mar - 19 Mar
Comfort Inn Hyannis - Cape Cod
Exterior

Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,023 reviews)
"Room was nice and spacious, very clean. Upstairs people was a little loud but other than that the stay was good. Would definitely stay again. "
United States
Celestina
The price is Rp1.257.643
Rp1.439.257 total
includes taxes & fees
12 Mar - 13 Mar
Cape Sands Inn
Exterior

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1,005 reviews)
"Lovely stay! One of the best hotels to stay in Hyannis. "
United States
Mary
The price is Rp2.107.032
Rp3.092.506 total
includes taxes & fees
12 Mar - 13 Mar
Hyannis Harbor Hotel
Exterior

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (995 reviews)
"Great place to stay "
United States
Lilian
The price is Rp1.922.382
Rp2.200.165 total
includes taxes & fees
16 Mar - 17 Mar
Holiday Inn Hyannis by IHG
Exterior

Sea Breeze Inn

Sea Breeze Inn
2.5 star property
1.8 km from Main Street Hyannis
7.8 out of 10, Good, (194 reviews)
"Nice place to stay "
United States
Kevin
The price is Rp1.135.583
Rp1.299.649 total
includes taxes & fees
5 Apr - 6 Apr
Sea Breeze Inn
Lobby

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
0.9 km from Main Street Hyannis
7.0 out of 10, Good, (1,001 reviews)
"The best staff abd it was clean and beautiful "
United States
Heather
The price is Rp1.492.376
Rp1.876.515 total
includes taxes & fees
15 Mar - 16 Mar
Hyannis Plaza Hotel
Family House, Private Bathroom, Pool View | Lounge

Sal's Place

Sal's Place
2.0 star property
2.5 km from Main Street Hyannis
The price is Rp6.745.200
Rp9.743.441 total
includes taxes & fees
12 Mar - 13 Mar
Sal's Place
Front of property

The Village Inn Cape Cod

The Village Inn Cape Cod
3.5 star property
6.1 km from Main Street Hyannis
10.0 out of 10, Exceptional, (224 reviews)
"It was so charming, would definitely stay there again! "
United States
Kyle
The price is Rp3.456.915
Rp3.956.566 total
includes taxes & fees
12 Mar - 13 Mar
The Village Inn Cape Cod
Outdoor pool, pool umbrellas, pool loungers

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
3.3 km from Main Street Hyannis
8.6 out of 10, Excellent, (478 reviews)
"The interior of the rooms were clean, the staff was friendly. "
United States
Maria Luisa
The price is Rp2.112.934
Rp3.383.392 total
includes taxes & fees
16 Mar - 17 Mar
Margaritaville Resort Cape Cod
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Main Street Hyannis Hotel Reviews

Hyannis Plaza Hotel

Hyannis Plaza Hotel

10/10 Excellent
"Love this place "
M 2-night trip
Posted 10 hours ago
Hyannis Plaza Hotel

Hotels near other Main Street Hyannis attractions

John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts

John F. Kennedy Hyannis Museum

4.4/5 (259 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
See properties
Cape Cod Maritime Museum which includes a bay or harbor and signage

Cape Cod Maritime Museum

You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the beautiful beaches in this family-friendly area or visit its seafood restaurants.
See properties

Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 187 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Courtyard Resort is one of the top choices for your stay based on our traveller data, and this hotel offers an indoor pool and free parking. Other good options within a short distance include Hyannis Travel Inn and Comfort Inn Hyannis - Cape Cod.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 187 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Whydah Pirate Museum and Cape Cod Maritime Museum feature captivating exhibits. Hyannis Harbor, Sandy Neck Lighthouse and West Parish Meetinghouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Veterans Memorial Park and Barnstable Dog Park are peaceful spots to stop and take in some fresh air.