Mark Twain Lake

A lake surrounded by trees and a dock extending into the water.

Top Hotel Deals

Cannon Dam Cabins

Cannon Dam Cabins

3 out of 5
42526 Cabin Rd Perry MO
Cannon Dam Cabins
The Junction Inn

The Junction Inn

2 out of 5
28804 MO-19 Perry MO
The Junction Inn
FairBridge Inn Express, Monroe City

FairBridge Inn Express, Monroe City

2 out of 5
3 Gateway Square Drive Monroe City MO
FairBridge Inn Express, Monroe City
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
Quality Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
Sleep Inn & Suites Hannibal West
Simple Rewards Inn Shelbina

Simple Rewards Inn Shelbina

2 out of 5
711 North Highway 15 Shelbina MO
Simple Rewards Inn Shelbina
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
Motel 6 Hannibal, MO
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2 out of 5
4070 Market St Hannibal MO
Days Inn by Wyndham Hannibal
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St Hannibal MO
Comfort Inn & Suites - Hannibal
See all 211 properties in Mark Twain Lake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.