A historic building with a prominent tower, two American flags, and a modern glass structure in the foreground.

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6 Nov - 8 Nov
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13 Nov - 15 Nov

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Our top choices for Mayo Clinic hotels

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

1. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
2.6 km from Mayo Clinic
9.6 out of 10, Exceptional, (1,000 reviews)
"Clean room, very nice staff and nice atmosphere."
United States
howard
The price is Rp1.989.819
Rp2.290.780 total
includes taxes & fees
7 Nov - 8 Nov
Home2 Suites by Hilton Rochester Mayo Clinic Area
A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

2. Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
2.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (321 reviews)
"Clean hotel, friendly staff, great location."
United States
Chee
The price is Rp2.395.404
Rp2.757.709 total
includes taxes & fees
13 Nov - 14 Nov
Residence Inn by Marriott Rochester Mayo Clinic Area South
An outdoor patio area with a concrete floor, wooden fence, and string lights.

3. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park, 1.8 km from Mayo Clinic
9.6 out of 10, Exceptional, (749 reviews)
"The staff was extremely helpful making for a comfortable stay."
United States
Brien
The price is Rp2.106.867
Rp2.425.530 total
includes taxes & fees
7 Nov - 8 Nov
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
A modern living room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a view of a cityscape through large windows.

4. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
9.6 out of 10, Exceptional, (654 reviews)
"Clean rooms, great staff, convenient location."
United States
Jennifer
The price is Rp3.069.565
Rp3.533.837 total
includes taxes & fees
27 Nov - 28 Nov
Hilton Rochester Mayo Clinic Area
A coffee shop interior with a wooden counter, menu boards, and seating area.

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Kutzky Park, 0.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (575 reviews)
"Excellent service, room was great and the lobby area is great for hanging out in the evenings!"
Canada
Cory
The price is Rp2.486.139
Rp2.862.169 total
includes taxes & fees
13 Nov - 14 Nov
TownePlace Suites by Marriott Rochester Mayo Clinic Area
A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

6. The Berkman

The Berkman
3.0 star property
Folwell, 1.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (451 reviews)
"Excellent service and wonderful room!"
United States
Suzette
The price is Rp3.273.719
Rp3.806.333 total
includes taxes & fees
1 Dec - 2 Dec
The Berkman
A modern living room with a fireplace, comfortable seating, and large windows.

7. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (560 reviews)
"Love love this hotel! Perfect for patients at Mayo and family"
United States
Amanda
The price is Rp1.905.435
Rp2.229.926 total
includes taxes & fees
25 Nov - 26 Nov
Staybridge Suites Rochester - Mayo Clinic Area by IHG
A modern indoor patio with a fire feature, seating, and large windows.

8. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (1,003 reviews)
"Great hotel and very clean!"
United States
James
The price is Rp2.068.758
Rp2.626.870 total
includes taxes & fees
6 Nov - 7 Nov
EVEN Hotel Rochester - Mayo Clinic Area by IHG
A hotel with a stone facade, multiple windows, and a sign indicating it is Candlewood Suites.

9. Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.5 star property
2.6 km from Mayo Clinic
9.2 out of 10, Wonderful, (528 reviews)
"Great place to stay, staff was very helpful."
United States
Kevin
The price is Rp1.941.729
Rp2.235.415 total
includes taxes & fees
15 Nov - 16 Nov
Candlewood Suites Rochester Mayo Clinic Area by IHG
A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

10. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
3.1 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,000 reviews)
"The staff was extremely friendly!"
United States
Ashley
The price is Rp1.221.656
Rp1.406.432 total
includes taxes & fees
28 Nov - 29 Nov
Econo Lodge Mayo Clinic Area
An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

11. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (540 reviews)
"Excellent and facility feels new. Staff very friendly"
United States
Lin
The price is Rp1.989.819
Rp2.290.780 total
includes taxes & fees
25 Nov - 26 Nov
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

12. Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester, 0.3 km from Mayo Clinic
9.2 out of 10, Wonderful, (185 reviews)
"Clean room and great location"
United States
Jennifer
The price is Rp3.069.565
Rp3.533.837 total
includes taxes & fees
7 Nov - 8 Nov
Broadway Plaza, Trademark Collection by Wyndham
A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

13. Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
2.9 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,003 reviews)
"Great stay"
United States
Susan
The price is Rp1.773.869
Rp2.042.167 total
includes taxes & fees
8 Nov - 9 Nov
Hampton Inn Rochester-South
An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

14. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 0.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,003 reviews)
"Nice stay"
United States
Arlan
The price is Rp2.522.433
Rp2.903.951 total
includes taxes & fees
27 Nov - 28 Nov
Hyatt House Rochester/Mayo Clinic Area
A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

15. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (807 reviews)
"Excellent employees"
United States
Connan
The price is Rp2.051.518
Rp2.361.810 total
includes taxes & fees
6 Nov - 7 Nov
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
A hotel entrance with a stone facade, a glass door, and a metal roof structure.

16. Aspen Suites

Aspen Suites
3.0 star property
1.2 km from Mayo Clinic
9.0 out of 10, Wonderful, (916 reviews)
"Room was clean, common areas were well kept, staff was friendly and accommodating."
United States
Lee
The price is Rp2.398.052
Rp2.898.797 total
includes taxes & fees
26 Nov - 27 Nov
Aspen Suites
A dining area with multiple wooden tables and chairs, a vase with flowers, a television, and a window with a view.

17. Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (1,005 reviews)
"Our stay was very nice"
United States
Anne
The price is Rp2.177.640
Rp2.507.008 total
includes taxes & fees
2 Nov - 3 Nov
Brentwood Inn & Suites
A spacious outdoor dining area with multiple tables and chairs, large windows, and a wooden ceiling structure.

18. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester, 0.4 km from Mayo Clinic
8.8 out of 10, Excellent, (1,001 reviews)
"Great location with easy access to Mayo Clinic and great food! The double queen room was clean and the beds were very comfortable. Will stay again!"
United States
Naomi
The price is Rp1.869.141
Rp2.151.871 total
includes taxes & fees
14 Nov - 15 Nov
Hotel Indigo Rochester – Mayo Clinic Area by IHG
A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

19. Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (965 reviews)
"Great place"
United States
Richard
The price is Rp2.144.068
Rp2.468.357 total
includes taxes & fees
13 Nov - 14 Nov
Hilton Garden Inn Rochester Downtown, MN
A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

20. Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area
2.5 star property
2.6 km from Mayo Clinic
8.8 out of 10, Excellent, (970 reviews)
"Good place, great valueI"
United States
Jessica
The price is Rp1.157.597
Rp1.352.282 total
includes taxes & fees
28 Nov - 29 Nov
Quality Inn & Suites Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels near Mayo Clinic

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

Home2 Suites by Hilton Rochester Mayo Clinic Area

3.0 star property
2.6 km from Mayo Clinic
View
A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

Residence Inn by Marriott Rochester Mayo Clinic Area South

3.0 star property
2.4 km from Mayo Clinic
View
An outdoor patio area with a concrete floor, wooden fence, and string lights.

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

3.0 star property
Kutzky Park, 1.8 km from Mayo Clinic
View
A modern living room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a view of a cityscape through large windows.

Hilton Rochester Mayo Clinic Area

3.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
View
A coffee shop interior with a wooden counter, menu boards, and seating area.

TownePlace Suites by Marriott Rochester Mayo Clinic Area

3.0 star property
Kutzky Park, 0.4 km from Mayo Clinic
View
9.6
Exceptional
1,000 reviews
9.6
Exceptional
321 reviews
9.6
Exceptional
749 reviews
9.6
Exceptional
654 reviews
9.6
Exceptional
575 reviews
The price is Rp1.989.819
Rp2.290.780 total
includes taxes & fees
7 Nov - 8 Nov
The price is Rp2.395.404
Rp2.757.709 total
includes taxes & fees
13 Nov - 14 Nov
The price is Rp2.106.867
Rp2.425.530 total
includes taxes & fees
7 Nov - 8 Nov
The price is Rp3.069.565
Rp3.533.837 total
includes taxes & fees
27 Nov - 28 Nov
The price is Rp2.486.139
Rp2.862.169 total
includes taxes & fees
13 Nov - 14 Nov
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • No WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • Yes, Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Top Mayo Clinic Hotel Reviews

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

10/10 Excellent
"So convenient to walk to convention center. Comfortable rooms."
lisa 1-night trip
Posted 13 hours ago
Hilton Garden Inn Rochester Downtown, MN

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 153 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area.
How many hotels should I expect to find near Mayo Clinic?
Expedia has 153 hotels and other accommodation options within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to review the best deals near Mayo Clinic.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Assisi Heights and Plummer House. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.