Search Spa Hotels in Mesagne

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mesagne Spa Hotels

Tonight
26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Mesagne hotels with a spa

Indoor spa tub
Tenuta Moreno

Tenuta Moreno

Tenuta Moreno
4.0 star property
Mesagne
8.4 out of 10, Very good, (58)
"Staff are lovely, especially Sonia in the restaurant! Pool is especially great - absolutely massive with loads of sun bed space."
United Kingdom
Alison
The price is Rp2.603.761
Rp2.864.137 total
includes taxes & fees
2 Jan - 3 Jan 2026
Tenuta Moreno
Couples treatment room(s), Turkish bath/hammam, body treatments
Hotel Monte Sarago

Hotel Monte Sarago

Hotel Monte Sarago
4.0 star property
Ostuni
9.2 out of 10, Wonderful, (268)
"Ecellent stay "
United Kingdom
maria
The price is Rp1.781.102
Rp2.077.565 total
includes taxes & fees
25 Jan - 26 Jan 2026
Hotel Monte Sarago
Couples treatment room(s), sauna, hot tub, steam room
Laurito Resort & Spa

Laurito Resort & Spa

Laurito Resort & Spa
3.0 star property
Oria
8.8 out of 10, Excellent, (38)
"I noticed that the hallways were not cleaned otherwise everything outstanding."
United States
Anonymous traveller
Laurito Resort & Spa
Couples treatment room(s), sauna, hot tub, steam room, body treatments
Ostuni Palace Hotel Bistrot & SPA

Ostuni Palace Hotel Bistrot & SPA

Ostuni Palace Hotel Bistrot & SPA
4.0 star property
Ostuni
9.2 out of 10, Wonderful, (145)
"Fantastic place!!!"
Australia
Joshua
The price is Rp2.195.840
Rp2.533.904 total
includes taxes & fees
4 Jan - 5 Jan 2026
Ostuni Palace Hotel Bistrot & SPA
Luxury Studio Suite (4) | Egyptian cotton sheets, premium bedding, down duvets, desk
FILIA SOLIS - Old Town SUITEs & SPA

FILIA SOLIS - Old Town SUITEs & SPA

FILIA SOLIS - Old Town SUITEs & SPA
Brindisi Historic Center
9.8 out of 10, Exceptional, (15)
"Had a wonderful stay at Filia Solis - the room was so beautiful and comfortable and the staff were incredibly communicative and helpful in providing recommendations. The location is great and very walkable. Would definitely return! "
Canada
Anonymous traveller
FILIA SOLIS - Old Town SUITEs & SPA
Exterior
B&B Palazzo Bernardini Suite

B&B Palazzo Bernardini Suite

B&B Palazzo Bernardini Suite
Lecce Historic Center
9.2 out of 10, Wonderful, (60)
"We had a wonderful stay here. Isabella did everything to make us happy and comfortable. Good room with a lovely terrace.perfect location in the city close to good restaurants and shops. Would recommend "
United States
Jerry
B&B Palazzo Bernardini Suite
Suite, Balcony, Garden View | Balcony
Vinilia Wine Resort

Vinilia Wine Resort

Vinilia Wine Resort
4.0 star property
Manduria
9.4 out of 10, Exceptional, (84)
"Stunning place in the countryside. Great service. Huge rooms. Lovely pool. Dinner was very creative and service was hyper attentive."
Canada
Tracey
Vinilia Wine Resort
Spa
Villa Neviera - Wine Resort and Spa

Villa Neviera - Wine Resort and Spa

Villa Neviera - Wine Resort and Spa
San Donaci
10.0 out of 10, Exceptional, (1)
The price is Rp1.582.958
Rp1.741.254 total
includes taxes & fees
12 Jan - 13 Jan 2026
Villa Neviera - Wine Resort and Spa
Sauna, hot tub, steam room, Turkish bath/hammam, body treatments
Le Dune Suite Hotel

Le Dune Suite Hotel

Le Dune Suite Hotel
4.0 star property
Porto Cesareo
8.6 out of 10, Excellent, (58)
"Perfect location for an excellent beach - with great amenities. Excellent half board package delivered a great dining experience. Within a reasonable walking distance to the town centre and the restaurants/bars/shopping/sights there. The whole hotel team went to great lengths to look after us and no ask was too much. Highly recommended."
United Kingdom
James
The price is Rp2.004.466
Rp2.204.913 total
includes taxes & fees
25 Jan - 26 Jan 2026
Le Dune Suite Hotel
Couples treatment room(s), deep-tissue massages, Swedish massages
B&B Giardini di Marzo

B&B Giardini di Marzo

B&B Giardini di Marzo
Lecce
9.6 out of 10, Exceptional, (22)
"Extremely friendly staff. Stefano made us feel welcomed. Conveniently located and very close to Lecce "
United States
Andre
B&B Giardini di Marzo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mesagne Hotel Reviews

Hotel Orientale

Hotel Orientale

10/10 Excellent
"A very good hotel in an excellent location. Clean, spacious, modern room. A very good breakfast buffet with a lot of selections. What is most noteworthy is the staff. Andre and his wife at the reception desk were welcoming, personable and very helpful with local knowledge and advice. At breakfast Toni and Antonio took great care to insure that all was in order and well stocked. Such was the care, that Toni actually would frequently stir the food in the steam trays to insure that the food still looked edible at the end of the breakfast hours. Though I travel 6 months of the year, that is something I rarely see. Highly recommend this Hotel."
Andrew 3-night trip
Posted 8 days ago
Hotel Orientale

Frequently asked questions

Looking to holiday at a spa hotel in Mesagne?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Enjoy the historical sites and restaurants in Mesagne—your day trip starts here. Take in the culture at the monuments and museums during your stay. Spa hotels are a great way to break out of your routine and add a layer of luxury to your stay.
What is the best spa hotel in Mesagne?
Tenuta Moreno is a top spa hotel featuring a rooftop terrace, a fitness centre, tennis courts and a bar. Enjoy a facial, body scrub or thalassotherapy at the on-site spa. Another popular spa hotel in Mesagne is Masseria Messapia Wine Resort & SPA.
How many spa hotels are there in Mesagne?
Among Expedia's 75 accommodation options in Mesagne, there are 3 spa hotels.
What's there to see and do in Mesagne?
When you're in Mesagne, enjoy exploring the sights and attractions here including Mesagne Castle, Court of Brindisi and Carrisiland Resort. If you have some spare time during your trip, you might want to check out Castle Dentice di Frasso and Cathedral of Brindisi.
What is a Mesagne spa hotel?
Spa hotels in Mesagne provide lodging and have a full on-site spa which offers services such as massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.