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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (360 reviews)
"Staff was really nice and helpful."
United States
rhonda
The price is Rp1.340.720
Rp1.522.220 total
includes taxes & fees
28 Feb - 1 Mar
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (21 reviews)
"Room was spacious and clean. Had a great stay. The restaurant was delicious. "
United States
James
The price is Rp1.602.495
Rp1.819.433 total
includes taxes & fees
1 Mar - 2 Mar
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (742 reviews)
"Thanks to the staff very help and kind. Very good stay. "
United States
Terry
The price is Rp1.055.817
Rp1.220.893 total
includes taxes & fees
28 Feb - 1 Mar
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,003 reviews)
"Everything was great. Will definitely stay again."
United States
Ethan
The price is Rp1.085.849
Rp1.247.098 total
includes taxes & fees
28 Feb - 1 Mar
Best Western On The River

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (168 reviews)
"Great place to stay!"
United States
Sandy
The price is Rp2.384.391
Rp3.315.904 total
includes taxes & fees
1 Mar - 2 Mar
Riverside Inn Hannibal

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"It was a good midway stop for us on our way to Memphis."
United States
Joel
The price is Rp1.794.889
Rp2.079.379 total
includes taxes & fees
8 Mar - 9 Mar
Sleep Inn & Suites Hannibal West

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (25 reviews)
"Nice room. Matched the pictures. Exactly what we were looking for."
United States
John
The price is Rp2.829.892
Rp3.250.132 total
includes taxes & fees
1 Mar - 2 Mar
Lighthouse Inn & Suites

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (519 reviews)
"Really cozy place to stay at!"
United States
Yufei
The price is Rp1.005.540
Rp1.140.785 total
includes taxes & fees
28 Feb - 1 Mar
Economy Inn Wentzville

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,001 reviews)
"Staff was awesome and accomodating. Room and price was great. "
United States
Anthony
The price is Rp1.168.102
Rp1.377.775 total
includes taxes & fees
8 Mar - 9 Mar
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very good, (39 reviews)
"Great location. Clean rooms, Staff very friendly."
United States
Charles
The price is Rp1.794.889
Rp2.061.525 total
includes taxes & fees
2 Mar - 3 Mar
Garden House Bed and Breakfast

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (675 reviews)
"Everything was clean and staff was friendly. Just needed some updates. "
United States
Georgia
The price is Rp1.247.540
Rp1.483.077 total
includes taxes & fees
16 Mar - 17 Mar
Comfort Inn & Suites - Hannibal

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
98 km from Mississippi River
6.8 out of 10, (1,004 reviews)
"Clean room very nice staff it’s nice"
United States
Mercedez
The price is Rp1.055.817
Rp1.213.352 total
includes taxes & fees
28 Feb - 1 Mar
Relax Inn Saint Charles

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,000 reviews)
"Overall, very nice stay"
United States
Cary
The price is Rp921.577
Rp1.058.331 total
includes taxes & fees
3 Mar - 4 Mar
Motel 6 Hannibal, MO

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,015 reviews)
"Good breakfast selections. Close to a good restaurant. "
United States
Steve
The price is Rp1.216.536
Rp1.409.356 total
includes taxes & fees
16 Mar - 17 Mar
Quality Inn & Suites Hannibal West

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (498 reviews)
"Great location for geode hunting. Irish Pub behind the hotel is the best."
United States
Marty
The price is Rp1.103.760
Rp1.236.312 total
includes taxes & fees
1 Mar - 2 Mar
Baymont by Wyndham Keokuk

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.8 out of 10, (35 reviews)
"I enjoyed it! And the owners were so sweet and understanding. I would absolutely stay there again!"
United States
Evelyn
The price is Rp1.131.232
Rp1.277.727 total
includes taxes & fees
1 Mar - 2 Mar
LAKEVIEWINN

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (224 reviews)
"Convenient stop and very pleasant , clean and friendly atmosphere"
United States
John David
The price is Rp1.173.130
Rp1.347.424 total
includes taxes & fees
28 Feb - 1 Mar
Days Inn by Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (154 reviews)
"Yes my stay was great"
United States
Aaron
The price is Rp955.263
Rp1.104.753 total
includes taxes & fees
28 Feb - 1 Mar
Howard Johnson BY Wyndham Hannibal

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,000 reviews)
"clean room - soft beds - friendly staff - very welcoming - lobby nice"
United States
Maxine
The price is Rp955.263
Rp1.097.119 total
includes taxes & fees
22 Mar - 23 Mar
Super 8 by Wyndham Hannibal

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,000 reviews)
"Great staff and the place is nice and clean and the breakfast is awesome."
United States
Kerry
The price is Rp1.125.367
Rp1.375.627 total
includes taxes & fees
2 Mar - 3 Mar
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
360 reviews
View
Interior
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
21 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
742 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,003 reviews
View
Honeymoon Room, River View | Egyptian cotton sheets, premium bedding, pillow-top beds
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
168 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Pear Tree Inn St. Louis Airport is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. You'll find it 69.9 mi (112.5 km) from Mississippi River. Other good options around the area include Clayton Plaza Hotel & Extended Stay and 21C Museum Hotel St Louis.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.