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2 Jan - 3 Jan
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Our top choices for Mississippi River hotels

Interior
The Eagles Nest Inn

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (19)
"It was very clean and very nice place to stay, has a very home and cozy feeling walking into the room."
United States
Bryan
The price is Rp1.594.935
Rp1.810.849 total
includes taxes & fees
9 Jan - 10 Jan
The Eagles Nest Inn
Exterior
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1003)
"Kind staff, clean rooms, plenty of parking."
United States
Megan
The price is Rp1.636.995
Rp1.896.459 total
includes taxes & fees
11 Jan - 12 Jan
Sleep Inn & Suites Hannibal West
Balcony
River's Edge Motel

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (358)
"Excellent stay !!! Quite "
United States
Bradley
The price is Rp1.334.400
Rp1.515.044 total
includes taxes & fees
11 Jan - 12 Jan
River's Edge Motel
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (165)
"Great place to stay!"
United States
Sandy
The price is Rp2.685.814
Rp3.659.425 total
includes taxes & fees
5 Jan - 6 Jan
Riverside Inn Hannibal
Deluxe Room | Down duvets, blackout curtains, iron/ironing board, free WiFi
Lighthouse Inn & Suites

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (24)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is Rp2.816.552
Rp3.234.809 total
includes taxes & fees
3 Jan - 4 Jan
Lighthouse Inn & Suites
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Best Western On The River

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1002)
"Great stay! Clean and cozy!!"
United States
Courtney
The price is Rp1.701.907
Rp1.954.641 total
includes taxes & fees
4 Jan - 5 Jan
Best Western On The River
Classic Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi
Town & Country Inn and Suites

Town & Country Inn and Suites

Town & Country Inn and Suites
2.5 star property
45.2 km from Mississippi River
9.2 out of 10, Wonderful, (899)
"great room and hotel"
United States
Amy
Town & Country Inn and Suites
Front of property
Garden House Bed and Breakfast

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.6 out of 10, Excellent, (38)
"Overall stay was great and the host chris is great aswell nothing bad to say about any aspect of our stay!"
United States
Josh
The price is Rp1.787.178
Rp2.052.668 total
includes taxes & fees
4 Jan - 5 Jan
Garden House Bed and Breakfast
Indoor spa tub
Stoney Creek Inn Quincy

Stoney Creek Inn Quincy

Stoney Creek Inn Quincy
2.0 star property
46.5 km from Mississippi River
8.8 out of 10, Excellent, (1001)
"Always love staying here"
United States
Ashlynn
Stoney Creek Inn Quincy
Exterior
Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
3.0 star property
46.1 km from Mississippi River
8.8 out of 10, Excellent, (612)
"Overall very nice property. "
United States
Jeffrey
The price is Rp1.985.753
Rp2.263.361 total
includes taxes & fees
11 Jan - 12 Jan
Holiday Inn Quincy East by IHG
Family Suite, Multiple Beds | Premium bedding, desk, laptop workspace, iron/ironing board
Heritage Hotel Quincy

Heritage Hotel Quincy

Heritage Hotel Quincy
2.0 star property
47.8 km from Mississippi River
8.8 out of 10, Excellent, (278)
"Room was very clean Breakfast was satisfying "
United States
Mark
The price is Rp1.419.229
Rp1.617.638 total
includes taxes & fees
17 Jan - 18 Jan
Heritage Hotel Quincy
Iron/ironing board, free cots/infant beds, rollaway beds, free WiFi
Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Quincy - Downtown
2.5 star property
47.8 km from Mississippi River
8.8 out of 10, Excellent, (450)
"It was in a very quite area and easy to find places to est. able to explore the Mississippi river. "
United States
James
The price is Rp1.631.154
Rp1.859.189 total
includes taxes & fees
31 Jan - 1 Feb
Quality Inn & Suites Quincy - Downtown
Lobby
Fairfield Inn & Suites Quincy

Fairfield Inn & Suites Quincy

Fairfield Inn & Suites Quincy
2.5 star property
46 km from Mississippi River
8.6 out of 10, Excellent, (336)
"We were very pleased with our stay. The room was clean and the staff was VERY friendly. We were also VERY impressed the breakfast. We would definitely stay there again."
United States
Julie
The price is Rp1.829.730
Rp2.085.526 total
includes taxes & fees
11 Jan - 12 Jan
Fairfield Inn & Suites Quincy
Lobby
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1008)
"Very nice place to stay during a snow storm. "
United States
Teresa
The price is Rp1.272.884
Rp1.474.637 total
includes taxes & fees
18 Jan - 19 Jan
Quality Inn & Suites Hannibal West
Bar (on property)
Oak Hill Inn & Suites

Oak Hill Inn & Suites

Oak Hill Inn & Suites
2.5 star property
71.8 km from Mississippi River
9.2 out of 10, Wonderful, (877)
"Room was clean, comfy bed, and very accommodating "
United States
Wendy
The price is Rp1.419.230
Rp1.617.567 total
includes taxes & fees
4 Jan - 5 Jan
Oak Hill Inn & Suites
Business Room, 2 Queen Beds | Desk, laptop workspace, blackout curtains, iron/ironing board
The Atrium Hotel on Third

The Atrium Hotel on Third

The Atrium Hotel on Third
3.5 star property
47.9 km from Mississippi River
8.4 out of 10, Very good, (759)
"Construction was very loud, lobby and pool were closed, breakfast and vending machines were limited, but staff was friendly and helpful and rooms were nice and clean"
United States
Makaio
The price is Rp2.177.654
Rp2.482.089 total
includes taxes & fees
3 Jan - 4 Jan
The Atrium Hotel on Third
Indoor pool, pool loungers
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (664)
"Below average facility. Needs some upgrades and could use a good cleaning. Staff was helpful."
United States
JACQUI
The price is Rp1.267.680
Rp1.505.970 total
includes taxes & fees
13 Jan - 14 Jan
Comfort Inn & Suites - Hannibal
Exterior
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
86.2 km from Mississippi River
9.4 out of 10, Exceptional, (853)
"Excellent location, very clean and comfortable, great hot breakfast, and amazing staff!"
United States
Shannon
The price is Rp1.835.570
Rp2.202.600 total
includes taxes & fees
10 Jan - 11 Jan
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Lobby sitting area
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1000)
"Very clean rooms and staff is very friendly "
United States
Sherrie
The price is Rp967.273
Rp1.110.888 total
includes taxes & fees
18 Jan - 19 Jan
Motel 6 Hannibal, MO
Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, free WiFi, bed sheets
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (220)
"Left before breakfast great cup of coffee"
United States
David
The price is Rp1.126.372
Rp1.293.639 total
includes taxes & fees
3 Jan - 4 Jan
Days Inn by Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mississippi River Hotel Reviews

St. Louis Airport Hotel

St. Louis Airport Hotel

10/10 Excellent
"This hotel was a good value. Spacious. Very clean. I'm guessing it is cheap because they don't have a shuttle from the airport. If that's a problem for you, I'll give you the cheat code: Enterprise car rental is right next door and they have a shuttle. "
David 2-night trip
Posted 10 hours ago
St. Louis Airport Hotel

Hotels near other Mississippi River attractions

Mark Twain Cave

4.4/5 (128 reviews)
Explore the great outdoors at Mark Twain Cave, a lovely green space in Hannibal. While in this trendy area, you can savour the top-notch restaurants.
See properties

Mark Twain Cave and Cameron Cave

4.5/5 (51 reviews)
You can find out about the history of Hannibal with a visit to Mark Twain Cave and Cameron Cave. While in this trendy area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and 2 bars. You'll find it 82.1 mi (132.1 km) from Mississippi River. Other good options around the area include Hampton Inn St. Louis-Downtown (At the Gateway Arch) and Magnolia Hotel St. Louis, a Tribute Portfolio Hotel.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.