Photo by Leonardo De Leon

Search Hotels in Otay Mesa West, San Diego

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top Trending Hotels Near Otay Mesa West, San Diego

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1425)
"Great place to stay beautiful casino! "
Sycuan Casino Resort

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1011)
"Cozy bed, very quiet and convenient"
The price is Rp1.825.040
Rp2.011.102 total
includes taxes & fees
17 Aug - 18 Aug
Days Inn by Wyndham San Diego-East/El Cajon

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.8 out of 10, Good, (1009)
"Great place "
The price is Rp1.678.385
Rp1.846.224 total
includes taxes & fees
25 Aug - 26 Aug
Super 8 by Wyndham El Cajon/San Diego

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very good, (1014)
"Staff was friendly, hotel was clean and breakfast was great"
The price is Rp2.007.544
Rp2.208.298 total
includes taxes & fees
17 Aug - 18 Aug
Best Western Plus La Mesa San Diego

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (381)
"Clean property and great breakfast!"
The price is Rp2.656.085
Rp2.926.873 total
includes taxes & fees
10 Aug - 11 Aug
SpringHill Suites by Marriott Chula Vista Eastlake

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1088)
"Very nice hotel"
The price is Rp3.074.541
Rp3.388.056 total
includes taxes & fees
5 Aug - 6 Aug
Ayres Hotel San Diego South - Chula Vista

Heritage Inn La Mesa

2.0 star property
6.6 out of 10, (1050)
"Familiar stay"
The price is Rp1.246.405
Rp1.374.320 total
includes taxes & fees
28 Jul - 29 Jul
Heritage Inn La Mesa

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1218)
"Clean rooms, simple checkin, plenty of parking"
Lamplighter Inn & Suites at SDSU

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1464)
"Clean, great staff. "
The price is Rp1.925.254
Rp2.117.780 total
includes taxes & fees
24 Aug - 25 Aug
Best Western Chula Vista/Otay Valley Hotel

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1315)
"Love the breakfast and convenient location. "
The price is Rp1.979.842
Rp2.177.827 total
includes taxes & fees
28 Jul - 29 Jul
La Quinta Inn by Wyndham San Diego Chula Vista

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (1149)
"Nice hotel to stay in "
The price is Rp1.352.322
Rp1.540.835 total
includes taxes & fees
28 Jul - 29 Jul
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Valli Hi Motel

2.5 star property
8.2 out of 10, Very good, (1020)
"Staff was friendly hotel was clean and easy day trips back and forth throughout San Diego area."
Valli Hi Motel

Best Western Americana Inn

2.5 star property
9.0 out of 10, Wonderful, (1121)
"It’s a very nice clean and friendly people in the property"
The price is Rp1.993.204
Rp2.267.269 total
includes taxes & fees
24 Aug - 25 Aug
Best Western Americana Inn

Chula Vista Inn

2.5 star property
6.6 out of 10, (1008)
"Nice hotel "
Chula Vista Inn

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1792)
"It’s was good experience staying in hotel "
The price is Rp1.253.020
Rp1.378.322 total
includes taxes & fees
28 Jul - 29 Jul
Hotel Palmeras Chula Vista

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1213)
"Great place to stay!"
The price is Rp1.644.850
Rp1.812.543 total
includes taxes & fees
28 Jul - 29 Jul
Hercor Hotel - Urban Boutique

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.4 out of 10, Good, (1008)
"Enjoyed our stay"
The price is Rp1.613.205
Rp1.777.671 total
includes taxes & fees
27 Jul - 28 Jul
Howard Johnson by Wyndham National City/San Diego South

SureStay Hotel by Best Western Chula Vista San Diego Bay

3.0 star property
7.8 out of 10, Good, (1464)
"Great place"
The price is Rp1.745.357
Rp1.923.297 total
includes taxes & fees
17 Aug - 18 Aug
SureStay Hotel by Best Western Chula Vista San Diego Bay

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very good, (948)
"Great location within walking distance from the places we wanted to visit."
The price is Rp1.392.439
Rp1.569.979 total
includes taxes & fees
15 Aug - 16 Aug
Berkshire Motor Hotel

The Rambler Motel

3.0 star property
9.0 out of 10, Wonderful, (1883)
"Very pleased with this stay."
The price is Rp1.939.105
Rp2.243.496 total
includes taxes & fees
17 Aug - 18 Aug
The Rambler Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most. Learn more about Otay Mesa West
Learn more about Otay Mesa West
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Mission Beach map

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach map

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter map

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach map

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Otay Mesa West Hotel Reviews

Frequently asked questions

What is Otay Mesa West like?

Otay Mesa West is a neighbourhood that travellers like for its cathedral.

How many hotels are there in the Otay Mesa West area?

When you want to find places to stay in San Diego, start by booking one of Expedia's 5 hotels and other accommodation options in Otay Mesa West.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes! The majority of room reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.

What is there to do around this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.