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Check availability on Panama City Luxury Hotels

Our top choices for Panama City luxury hotels

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1007)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is Rp4.644.234
Rp5.108.658 total
includes taxes & fees
4 Jan - 5 Jan 2026
JW Marriott Panama

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1005)
"Great staff, super accommodating. Best place to stay in Panama!"
United States
Sebastian
The price is Rp3.664.617
Rp4.031.162 total
includes taxes & fees
20 Dec - 21 Dec
Bristol Panama, a Registry Collection Hotel

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1004)
"I loved everything about my stay "
United States
Stephanie
The price is Rp3.671.775
Rp4.038.952 total
includes taxes & fees
3 Jan - 4 Jan 2026
Waldorf Astoria Panama

American Trade Hotel

American Trade Hotel
4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (605)
"Excellent service and great rooms on a beautiful and historical building"
Canada
Manuel
The price is Rp4.853.974
Rp5.339.371 total
includes taxes & fees
4 Jan - 5 Jan 2026
American Trade Hotel

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1003)
"Amazing amazing service"
United States
KFIR
The price is Rp2.646.714
Rp2.911.385 total
includes taxes & fees
20 Dec - 21 Dec
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1002)
"Room was spacious and comfortable. Views are magnificent. Servece is excellent. Breakfast is good, but they were periodically running out some food "
United States
alexandra
The price is Rp3.098.653
Rp3.408.601 total
includes taxes & fees
9 Jan - 10 Jan 2026
Hilton Panama

Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very good, (1000)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1014)
"I loved my stay! "
United States
Jenniffer Gonzalez De La
The price is Rp2.911.552
Rp3.202.690 total
includes taxes & fees
10 Jan - 11 Jan 2026
Las Americas Golden Tower Panama

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1003)
"Room was clean and helpful staff."
United States
Felicia
The price is Rp2.359.571
Rp2.595.611 total
includes taxes & fees
19 Dec - 20 Dec
Marriott Panama Hotel

Doubletree By Hilton Panama City El Carmen

Doubletree By Hilton Panama City El Carmen
4.5 star property
Bella Vista
8.0 out of 10, Very good, (995)
"This hotel has been closed down. "
United States
Anonymous traveller
Doubletree By Hilton Panama City El Carmen
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Panama City Hotel Reviews

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Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 23 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Megapolis Hotel Panamá and W Panama are other upscale choices for your trip.
How many luxury hotels should I expect to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 23 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Panama City are July, August, June and November, with each month seeing an average of 369 mm of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Crown Casino.
How can I get around Panama City?
It's easier to get around town in style when you know your options. Walk to nearby metro stations such as Iglesia del Carmen Station, Vía Argentina and Santo Tomas Station. If you want to explore the larger area, hop on a train at Panama City Passenger Station.