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Our top choices for Panama City luxury hotels

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (645 reviews)
  • cleanliness
    Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
"The hotel is new and feels luxurious in every way."
United States
Nikhil
The price is Rp5.303.898
Rp5.834.288 total
includes taxes & fees
1 Jun - 2 Jun
Sofitel Legend Casco Viejo, Panama City

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (297 reviews)
  • cleanliness
    Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
"This is an excellent historic property, extremely well renovated and updated to a modern luxury hotel property."
United States
Marvin
The price is Rp5.377.563
Rp5.915.319 total
includes taxes & fees
2 Jun - 3 Jun
Hotel La Compañía Casco Antiguo

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1,014 reviews)
"Well located and nice terrace & pool"
United Kingdom
Victor
The price is Rp2.909.866
Rp3.200.853 total
includes taxes & fees
10 May - 11 May
Central Hotel Panama Casco Viejo

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,014 reviews)
  • cleanliness
    Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
"The ocean view from the infinite pool is amazing."
Canada
Charmaine Marie
The price is Rp4.423.382
Rp4.865.720 total
includes taxes & fees
6 Jun - 7 Jun
JW Marriott Panama

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
"Luxury in Panama"
United States
Kelinde
The price is Rp4.552.512
Rp5.007.763 total
includes taxes & fees
5 Jun - 6 Jun
Waldorf Astoria Panama

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
4.0 star property
Veracruz
7.6 out of 10, Good, (1,012 reviews)
"Beautiful and luxurious"
United States
Jemicia Olivia
The price is Rp4.731.912
Rp4.731.912 total
includes taxes & fees
8 Jun - 9 Jun
Dreams Playa Bonita Panama - All Inclusive

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (693 reviews)
  • cleanliness
    Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
"This property is luxury and comfort."
United States
Amelia
The price is Rp4.146.920
Rp4.561.612 total
includes taxes & fees
15 May - 16 May
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,004 reviews)
  • cleanliness
    Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
"April 2026 — Luxury, romance, and family comfort with incredible bay views (and excellent accessibility)"
United States
Annie
The price is Rp3.963.190
Rp4.359.509 total
includes taxes & fees
7 Jun - 8 Jun
Hilton Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1,002 reviews)
  • cleanliness
    Oceanfront luxury beckons with private beach, indulgent spa services, and refined dining at this beachfront Panama retreat.
"Rooms were great! A/C felt AMAZING! Staff SUPER NICE AND FRIENDLY! FOOD AMAZING! There was literally nothing we ate that we did not love! We added the Premium all inclusive package when we arrived for a great price! We ate at all the restaurants, buffets and had top shelf liquor ! I would for sure stay here again! "
United States
Akashia
The price is Rp3.492.946
Rp3.842.240 total
includes taxes & fees
4 Jun - 5 Jun
The Westin Playa Bonita Panama

American Trade Hotel

American Trade Hotel
4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (726 reviews)
  • cleanliness
    A colonial gem in Panama City offering luxurious comfort, exquisite dining, and personalised service in a historic district.
"Very vintage and luxurious"
United States
haim
The price is Rp3.832.066
Rp4.215.273 total
includes taxes & fees
1 Jun - 2 Jun
American Trade Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Panama City Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 24 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Renaissance Panama City Hotel and Hyatt Regency Panama City are other upscale choices for your trip.
How many luxury hotels should I expect to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 24 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Panama City are July, August, June and November, with each month seeing an average of 369 mm of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Multicentro Panama.
How can I get around Panama City?
It's easier to get around town in style when you know your options. Walk to nearby metro stations such as Iglesia del Carmen Station, Vía Argentina and Santo Tomas Station. If you want to explore the larger area, hop on a train at Panama City Passenger Station.