A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

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Check availability on Panama City Luxury Hotels

Tonight
9 Sept - 10 Sept
Tomorrow
10 Sept - 11 Sept
This weekend
11 Sept - 13 Sept
Next weekend
18 Sept - 20 Sept

Our top choices for Panama City luxury hotels

A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.

1. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
  • Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
Rp6.347.520
Rp6.982.272 total
includes taxes & fees
6 Oct - 7 Oct
Sofitel Legend Casco Viejo, Panama City
A restaurant with multiple dining tables, chairs, and a central water feature.
A historic building with ornate stonework and a balcony with plants.
A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

2. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
  • Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
Rp4.930.789
Rp5.423.868 total
includes taxes & fees
9 Oct - 10 Oct
Hotel La Compañía Casco Antiguo
A poolside area with lounge chairs and a view of the ocean.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A terrace with seating and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.

3. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
Rp4.781.798
Rp5.259.978 total
includes taxes & fees
25 Sept - 26 Sept
JW Marriott Panama
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.

4. W Panama

W Panama
Bella Vista
  • Lavish urban retreat offers 3 hot tubs, poolside luxury, and concierge services in Panama city.
Rp4.076.518
Rp4.484.170 total
includes taxes & fees
25 Sept - 26 Sept
W Panama
A resort with a large swimming pool, thatched-roof structures, and palm trees.
A resort with a pool, palm trees, and a building with a red roof.
An outdoor dining area with tables and chairs, overlooking a body of water and a forested island.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.

5. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
Rp4.906.986
Rp4.906.986 total
includes taxes & fees
1 Oct - 2 Oct
Dreams Playa Bonita Panama - All Inclusive
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
An outdoor seating area with wicker chairs and tables, large windows offering a city view at dusk.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.

6. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
  • Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
Rp4.687.996
Rp5.156.796 total
includes taxes & fees
27 Sept - 28 Sept
Waldorf Astoria Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A modern interior with a spiral staircase, a large window, and a seating area.
A modern bar area with seating and a view of the city.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.

7. Hilton Panama

Hilton Panama
Bella Vista
  • Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
Rp4.149.515
Rp4.564.466 total
includes taxes & fees
3 Oct - 4 Oct
Hilton Panama
A hotel entrance with a central water feature, seating areas, and potted plants.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.
A pool with a central water feature, surrounded by seating areas and potted plants.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.

8. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
  • Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
Rp4.740.011
Rp5.214.012 total
includes taxes & fees
1 Oct - 2 Oct
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A multi-story building with balconies, arched windows, and decorative railings.
A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.
A building with a balcony and a street view.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.

9. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
Rp3.233.709
Rp3.557.080 total
includes taxes & fees
9 Oct - 10 Oct
Central Hotel Panama Casco Viejo
A rooftop pool with a city view, modern architecture, and outdoor seating.
A spacious lobby with a modern design, featuring a sofa, chairs, and large potted plants.
A narrow street with multi-story buildings, balconies, and a central building with a red roof.
A high-rise building with a view of the ocean and a parking area with palm trees.

10. The Westin Panama

The Westin Panama
Costa del Este
Rp3.927.352
Rp4.320.087 total
includes taxes & fees
12 Sept - 13 Sept
The Westin Panama
View all properties

Top Panama City Hotel Reviews

Marriott Panama Hotel

Marriott Panama Hotel

10/10 Excellent
"Everything was good"
Andrew 5-night trip
Posted 6 hours ago
Marriott Panama Hotel
JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"The hotel is beautiful with really nice and spacious rooms. The pool area is unbelievable. Plus, a great location."
Geneva Smith 5-night trip
Posted 17 hours ago
JW Marriott Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

10/10 Excellent
"Fue una estadía placentera"
Carlos 2-night trip
Posted 17 hours ago
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

8/10 Good
"Thanks"
natalia 3-night trip
Posted 20 hours ago
Las Americas Golden Tower Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

8/10 Good
"El lugar está céntrico pero fue difícil conseguir hielo paras habitaciones que están más arriba del piso 14 hay que ir al restaurante la piscina es pequeña"
Barbara 2-night trip
Posted 1 day ago
Decapolis Hotel Panama City
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

10/10 Excellent
"Excelente ubicación y precio"
Geiner 4-night trip
Posted 1 day ago
Hospedium Princess Hotel Panama
Renaissance Panama City Hotel

Renaissance Panama City Hotel

10/10 Excellent
"Great location and very clean"
Reubin 6-night trip
Posted 2 days ago
Renaissance Panama City Hotel

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 24 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Megapolis Hotel Panamá and Hyatt Regency Panama City are other upscale choices for your trip.
How many luxury hotels should I expect to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 24 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Panama City are July, August, June and November, with each month seeing an average of 369 mm of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Multicentro Panama.
How can I get around Panama City?
It's easier to get around town in style when you know your options. Walk to nearby metro stations such as Iglesia del Carmen Station, Vía Argentina Station and Santo Tomás Station. If you want to explore the larger area, hop on a train at Panama City Passenger Station.