Search Spa Hotels in San Diego

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on San Diego Spa Hotels

Our top choices for San Diego hotels with a spa

Body treatments, aromatherapy, body wraps, body scrubs, facials
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1855)
"Enjoyed my stay"
United States
Brandon
The price is Rp1.377.338
Rp2.416.663 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton San Diego Bayfront
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 star property
National City
9.2 out of 10, Wonderful, (3503)
"Great friendly staff "
United States
mohammed
The price is Rp1.936.250
Rp2.133.650 total
includes taxes & fees
16 Dec - 17 Dec
Best Western Plus Marina Gateway Hotel
Exterior
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
Mission Bay
8.4 out of 10, Very good, (1568)
"Loved our stay "
United States
Jeremy
The price is Rp1.938.289
Rp3.111.298 total
includes taxes & fees
18 Dec - 19 Dec
Hyatt Regency Mission Bay Spa and Marina
Facials, 2 treatment rooms, massages
The Westin San Diego Bayview

The Westin San Diego Bayview

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1057)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is Rp2.254.595
Rp3.097.527 total
includes taxes & fees
19 Dec - 20 Dec
The Westin San Diego Bayview
Couples treatment room(s), body treatments, hot stone massages
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2957)
"Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego."
United States
Eric
The price is Rp2.537.253
Rp2.916.445 total
includes taxes & fees
14 Dec - 15 Dec
Legacy Resort Hotel & Spa
Dinner served
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2046)
"It was an amazing stay "
United States
Alejandra
The price is Rp3.104.379
Rp4.353.461 total
includes taxes & fees
4 Jan - 5 Jan 2026
Omni San Diego Hotel at the Ballpark
Premier Room, 1 King Bed | Premium bedding, in-room safe, desk, blackout curtains
Handlery Hotel

Handlery Hotel

3.5 star property
Mission Valley
8.2 out of 10, Very good, (2219)
"Staff was amazing and very accommodating. Always recommended staying here. "
United States
Taja
Handlery Hotel
Outdoor pool
Humphreys Half Moon Inn

Humphreys Half Moon Inn

3.5 star property
Point Loma
9.2 out of 10, Wonderful, (2690)
"Great stay !!"
United States
Caleb Scott
The price is Rp2.484.724
Rp3.189.619 total
includes taxes & fees
14 Dec - 15 Dec
Humphreys Half Moon Inn
Property grounds
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4.0 star property
Mission Bay
8.6 out of 10, Excellent, (2351)
"Amazing place!"
United States
Barak Ben
The price is Rp2.157.041
Rp3.361.882 total
includes taxes & fees
16 Dec - 17 Dec
Paradise Point Resort & Spa
Hot stone massages, prenatal massages, sports massages, body scrubs
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4.0 star property
Mission Bay
8.4 out of 10, Very good, (1308)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is Rp1.962.098
Rp3.007.088 total
includes taxes & fees
17 Dec - 18 Dec
San Diego Mission Bay Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top San Diego Hotel Reviews

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

10/10 Excellent
"Leigh at the front desk."
Randolph 1-night trip
Posted 18 hours ago
Hampton Inn & Suites by Hilton San Diego SeaWorld

Explore a world of travel with Expedia

Frequently asked questions

Looking to holiday at a spa hotel in San Diego?
Treat yourself to some pampering and book a hotel with a spa. Travellers love the historical sites and fascinating museums in San Diego so get ready for a cultural tour. Enjoy the theatres and sea views during your holiday. Spa hotels are a great way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in San Diego?
Legacy Resort Hotel & Spa is a top spa hotel featuring a fitness centre, a bar, an outdoor pool and a restaurant. Spend an afternoon at the spa where you'll find facials, body scrubs and Swedish massages. Other popular spa hotels in San Diego include Paradise Point Resort & Spa and Handlery Hotel.
How many spa hotels are there in San Diego?
Among Expedia's 6024 accommodation options in San Diego, there are 14 spa hotels.
What's there to see and do in San Diego?
Take in some sights and attractions while you're in San Diego by visiting San Diego Zoo, Petco Park and Port of San Diego. If you have extra time while you're in the area, you might want to stop by Mission Bay and San Diego Civic Theatre.
What is a San Diego spa hotel?
Spa hotels in San Diego have full on-site spas and offer services such as couples massages and a range of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your holiday.