Santa Clara Holidays

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Where to stay in Santa Clara

Find the best Santa Clara areas and neighborhoods for the activities you enjoy most. Learn more about Santa Clara
View of the Panama City Old Town

Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Top hotels in Santa Clara

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is Rp2.168.388 per night from 2 Jul to 3 Jul
Rp2.168.388
Rp2.385.227 total
2 Jul - 3 Jul
includes taxes & fees
9/10 Wonderful! (5,539 reviews)
"My stay at the Riu in Panama was excellent , customer service, meals and staff was outstanding. I highly recommend this property"

Reviewed on 4 Jun 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
The price is Rp2.353.677 per night from 29 Jun to 30 Jun
Rp2.353.677
Rp2.707.627 total
29 Jun - 30 Jun
includes taxes & fees
8.6/10 Excellent! (2,575 reviews)
"I highly recommend to persons who want a hassle free trip to and from the airport."

Reviewed on 3 Jun 2026

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
The price is Rp5.380.398 per night from 10 Jun to 11 Jun
Rp5.380.398
Rp5.380.398 total
10 Jun - 11 Jun
includes taxes & fees
7.6/10 Good! (1,001 reviews)
"Nice"

Reviewed on 1 Jun 2026

Dreams Playa Bonita Panama - All Inclusive
See all 1,763 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Clara holiday package cost?
Custom make your Santa Clara holiday package from as little as . Pick from any combination of hotels, flights and rental cars to craft the escape of your dreams. Be sure to add on some tours and experiences!
How do I get a cheap travel package to Santa Clara?
One of the easiest ways to save cash (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we've got them all. Select the combination that best fits you and watch your savings grow. Of course, a travel package is never a one-size-fits-all. That's why we offer more than 550 air carriers and 1,000,000 hotels throughout the world, which lets you customize your Santa Clara getaway.
Where should I stay in Santa Clara?
Most travellers who visit Santa Clara include Miraflores Locks and Metropolitan Cathedral of Panama on their must-see lists. Why not select a hotel close to one of these main attractions?
How far in advance should I book my Santa Clara holiday?
Savvy travellers always book early. Air carriers generally advertise flights up to a year prior to departure, and this is a fantastic opportunity to score some of the cheapest prices. Just been told you should take some holiday time next week? No need to worry. Expedia are never short on fantastic deals to whisk you away on the getaway of your dreams, at an affordable price.
What does an Expedia Santa Clara travel package include?
It comes down to what you're looking for. If you're travelling solo, you might decide to combine hotels and flights. Bringing the whole family to Santa Clara? A travel package including flights, hotels and rental cars might suit you better. Expedia gives you the flexibility and freedom to tailor-make your travel package.
What should I know before booking a Santa Clara travel package?
When you book your flights, hotels and car rentals together, you'll pick up awesome discounts. Whether you're organising a beach break in a villa or prefer to stay in an upscale city hotel, Expedia can make it happen for less.
Can I choose my airline with a Santa Clara Expedia holiday package?
Yes, you can. We offer more than 550 airline partners throughout the world, so opt for the carrier that fits your budget and travel needs.
If I'm not able to travel, can I cancel my Santa Clara holiday package?
Because we understand life is full of surprises, the answer is yes. For further details, check out our Customer Service Portal. But generally speaking, if you've made your booking in the last 24 hours, you may be able to change or cancel it for no charge. Your hotel, airline or car rental company may impose a fee if you made your booking a while ago.

Popular places to visit

Panoramic view at the Downtown of Panama City - Panama

Cinta Costera

After visiting Cinta Costera, make a plan to see the other sights and activities in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera

Albrook Shopping Mall

You can find the perfect gifts to bring home with a trip to Albrook Shopping Mall, a favourite shopping spot in Ancon. Amble around this culturally rich area's seaside and enjoy its top-notch restaurants.

Albrook Shopping Mall

Estadio Rommel Fernandez

Catch an event at Estadio Rommel Fernandez during your trip to Panama City. Stroll along the seaside or visit the shops in the area.

Estadio Rommel Fernandez

Things to do

Panama City: POIN Swing Experience

Panama City: POIN Swing Experience

Rp569.582
per adult
100% of travellers recommend
Panama City: POIN Swing Experience
Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

Rp739.038
per adult
96% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City

All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City

Rp1.756.656
per adult
96% of travellers recommend
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.