Santa Clara Holidays

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Where to stay in Santa Clara

Find the best Santa Clara areas and neighborhoods for the activities you enjoy most. Learn more about Santa Clara
View of the Panama City Old Town

Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Top hotels in Santa Clara

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is Rp2.038.167 per night from 8 Mar to 9 Mar
Rp2.038.167
Rp2.241.984 total
8 Mar - 9 Mar
includes taxes & fees
9/10 Wonderful! (4,997 reviews)
Everything and everyone were excellent staff and room will Highly recommend and looking forward to another stay there

Reviewed on 21 Feb 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
The price is Rp2.013.050 per night from 5 Mar to 6 Mar
Rp2.013.050
Rp2.214.355 total
5 Mar - 6 Mar
includes taxes & fees
8.4/10 Very Good! (2,424 reviews)
Not really clean, but people were friendly and bed was comfortable.

Reviewed on 17 Feb 2026

Crowne Plaza Panama Airport by IHG
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is Rp1.823.904 per night from 24 Feb to 25 Feb
Rp1.823.904
Rp2.006.294 total
24 Feb - 25 Feb
includes taxes & fees
7.6/10 Good! (1,013 reviews)
Yes nice and clean

Reviewed on 21 Feb 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
See all 1,541 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Clara holiday package cost?
Custom make your Santa Clara holiday package from as little as . Pick from any combination of hotels, flights and rental cars to craft the escape of your dreams. Be sure to add on some tours and experiences!
How do I get a cheap travel package to Santa Clara?
One of the easiest ways to save cash (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we've got them all. Select the combination that best fits you and watch your savings grow. Of course, a travel package is never a one-size-fits-all. That's why we offer more than 550 air carriers and 1,000,000 hotels throughout the world, which lets you customize your Santa Clara getaway.
Where should I stay in Santa Clara?
Most travellers who visit Santa Clara include Miraflores Locks and Metropolitan Cathedral of Panama on their must-see lists. Why not select a hotel close to one of these main attractions?
How far in advance should I book my Santa Clara holiday?
Savvy travellers always book early. Air carriers generally advertise flights up to a year prior to departure, and this is a fantastic opportunity to score some of the cheapest prices. Just been told you should take some holiday time next week? No need to worry. Expedia are never short on fantastic deals to whisk you away on the getaway of your dreams, at an affordable price.
What does an Expedia Santa Clara travel package include?
It comes down to what you're looking for. If you're travelling solo, you might decide to combine hotels and flights. Bringing the whole family to Santa Clara? A travel package including flights, hotels and rental cars might suit you better. Expedia gives you the flexibility and freedom to tailor-make your travel package.
What should I know before booking a Santa Clara travel package?
When you book your flights, hotels and car rentals together, you'll pick up awesome discounts. Whether you're organising a beach break in a villa or prefer to stay in an upscale city hotel, Expedia can make it happen for less.
Can I choose my airline with a Santa Clara Expedia holiday package?
Yes, you can. We offer more than 550 airline partners throughout the world, so opt for the carrier that fits your budget and travel needs.
If I'm not able to travel, can I cancel my Santa Clara holiday package?
Because we understand life is full of surprises, the answer is yes. For further details, check out our Customer Service Portal. But generally speaking, if you've made your booking in the last 24 hours, you may be able to change or cancel it for no charge. Your hotel, airline or car rental company may impose a fee if you made your booking a while ago.

Popular places to visit

Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Cinta Costera

4/5(5 reviews)

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera

Albrook Shopping Mall

4/5(5 reviews)

You can find the perfect gifts to bring home with a trip to Albrook Shopping Mall, a favourite shopping spot in Ancon. Amble around this culturally rich area's seaside and enjoy its top-notch restaurants.

Albrook Shopping Mall

Crown Casino

Why not roll the dice with a visit to Crown Casino during your visit to Panama City? Stroll along the seaside or visit the shops in this vibrant area.

Crown Casino

Things to do

Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

Rp1.329.096
per adult
100% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City

All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City

Rp1.663.695
per adult
96% of travellers recommend
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Panama Canal Half Transit Experience

Panama Canal Partial Transit

Rp2.523.600
per adult
84% of travellers recommend
Panama Canal Partial Transit
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.