Santa María Holidays

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    Save up to Rp16.000.000 when you book a flight and hotel together*

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Top hotels in Santa María

Sun Hotel

Sun Hotel

3.5 out of 5
Encarnacion Itapúa
The price is Rp1.267.578 per night from 11 Nov to 12 Nov
Rp1.267.578
Rp1.394.354 total
11 Nov - 12 Nov
includes taxes & fees
Sun Hotel
Carnaval Hotel Casino

Carnaval Hotel Casino

3.5 out of 5
Av. Irrazabal, 750 Encarnacion
Fully refundableReserve now, pay when you stay
The price is Rp1.157.260 per night from 15 Nov to 16 Nov
Rp1.157.260
Rp1.272.986 total
15 Nov - 16 Nov
includes taxes & fees
9.4/10 Exceptional! (213 reviews)
"The best thing of the property was the Staff. They were accommodating and always asking you. How was your day very very friendly."

Reviewed on 12 Sept 2026

Carnaval Hotel Casino
Alula Hotel Encarnacion

Alula Hotel Encarnacion

4.5 out of 5
1848 Gral Aquino Encarnación Itapúa
Get rates
Alula Hotel Encarnacion
See all 36 properties in Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Santa María

Full-day guided adventure in the Misiones jungle

Full-day guided adventure in the Misiones jungle

Rp6.827.080
per adult
Full-day guided adventure in the Misiones jungle
See all activities in Santa María

Frequently asked questions

How much does a Santa María holiday package cost?
Offering great value package deals on Expedia, you'll be pleasantly surprised at how much a holiday to Santa María costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Santa María?
January, February and April are the best times to search for cheap Santa María holiday packages. Opting to travel in quieter months means you can usually find better prices on flights and hotels.
How many days is enough for Santa María?
The ideal length for your Santa María holiday depends on what you'd like to see and do. Typically, a handful of days to a week will give you plenty of time to check out all the main attractions and explore some hidden spots along the way.
How to find the best Santa María package deals?
Use Expedia's handy filters to find some fabulous Santa María package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your trip for midweek, or look for Santa María package deals in the off-peak season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to lock in your holiday package well in advance.
Is it cheaper to book a Santa María holiday as a package?
An Expedia holiday package could save you hundreds of dollars when compared to booking hotels and flights separately. Better still, you can customise your Santa Marían escape to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a holiday package to Santa María?
If you have your Santa María holiday dates locked in, book as early as you can to snap up some terrific deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous trips? Our last-minute deals are great for setting off on a whim.
How to plan a trip to Santa María?

  1. Choose when to travel: Check your calendar and pack your bags. Your preferred time of year and the type of activities on offer will also help you decide when to escape to Santa María.
  2. Set a budget: Consider expenses like flights, transportation and food when working out how much to set aside for your trip to Santa María. Then, select a property that matches your budget, whether that's a low-cost stay or a swankier getaway.
  3. Work out your trip length: Think about how long you want to spend exploring Santa María. Plan your days so you can get to all the attractions and activities you're interested in at a leisurely pace.
  4. Bundle your hotel and flights: Awesome destination, check. Length of stay, check. Now all that's left is to find a Santa María holiday package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.