Santa Maria Holidays

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Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

A statue of a soldier on a pedestal with a building in the background.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Moorish Clock Tower while you're in town.

A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana

Restaurants and river views are some things travellers note about Puerto Santa Ana. Check out Santa Ana Hill or Numa Pompilio Llona Street while you're familiarising yourself with the larger area.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

1 out of top 10 points of interest in this area

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

A densely packed hillside cityscape with colorful buildings and a prominent tower against a sunset sky.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Alban Borja Commercial Center.

Top hotels in Santa Maria

Oro Verde Guayaquil

Oro Verde Guayaquil

9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
Rp1.687.010
Rp1.900.106 total
26 Sept - 27 Sept
9.6/10 Exceptional! (1,003 reviews)
"Great staff, clean room, wonderful breakfast"

Reviewed on 17 Sept 2026

Oro Verde Guayaquil
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

Calle Numa Pompilio Llona S N Guayaquil Guayas
Rp2.045.722
Rp2.294.689 total
16 Oct - 17 Oct
9.4/10 Exceptional! (1,002 reviews)
"We arrived after a flight diverted from Quito. We checked best hotel in Guayaquil and this was right. Staff is great, food wonderful, and we felt safe in this city that has not a great safe review"

Reviewed on 19 Sept 2026

Wyndham Guayaquil Puerto Santa Ana
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Fully refundable
Rp1.793.558
Rp2.017.309 total
26 Sept - 27 Sept
9.4/10 Exceptional! (1,002 reviews)
"Excellent service. Comfortable beds which is a priority above all since I travel internationally each month. Great food and service"

Reviewed on 19 Sept 2026

Holiday Inn Guayaquil Airport by IHG
See all 444 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Maria holiday package cost?
Get set to book, because a getaway to Santa Maria starts from a tempting . When you combine your hotels, flights and car rentals into a travel package, you'll enjoy the lowest prices.
How do I get a cheap travel package to Santa Maria?
Bundle your hotels and flights with Expedia to save big on your next trip. With more than 550 air carriers and 1,000,000 hotels worldwide, your Santa Maria holiday package can be customized exactly to suit your travel style. With all that extra cash, why not add a few fun activities and tours? It's an easy way to unlock even more savings. Your dream holiday in Santa Maria is closer than you thought!
Where should I stay in Santa Maria?
Make sightseeing easy by staying someplace right around the corner from Santa Maria's biggest attractions. Malecon 2000 and Banco Pichincha Monumental Stadium are two visitor favourites.
How far in advance should I book my Santa Maria holiday?
Your safest bet is to book early. Airlines usually release flight tickets nearly 12 months prior to departure, and this is a great opportunity to score some rock-bottom prices. Just been told you should take your holiday time next month? No sweat. Expedia are never short on fantastic bargains to help you have the getaway of your dreams, at an affordable price.
What does an Expedia Santa Maria travel package include?
Select from any combination of flights, hotels and rental cars. Once you've made your booking, you can add activities and experiences. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to arranging your dream Santa Maria escape.
What should I know before booking a Santa Maria travel package?
Get set to save with an Expedia travel package. Combine your flights, rental cars and hotels and enjoy exciting discounts. Hotels aren't your only choice, however. Book with us and choose from beach villas, creek-side mountain cabins and just about everything in between!
Can I choose my airline with a Santa Maria Expedia holiday package?
Expedia offers access to more than 550 airline partners globally, so you certainly can. Just pick your preferred air carrier and put together your ideal Santa Maria escape.
If I'm not able to travel, can I cancel my Santa Maria holiday package?
Yes, you can cancel your Santa Maria booking if your travel plans have been upended. Whether you'll incur a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking for free if you booked in the last 24 hours. Head to our Customer Service Portal to learn more.

Things to do

City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

Rp1.129.460
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Half Day Tour Guayaquil Pearl of the Pacific

Half Day Walking Tour of Guayaquil Pearl of the Pacific

Rp1.754.700
per adult
Half Day Walking Tour of Guayaquil Pearl of the Pacific
Ecuador Paragliding Guayaquil

Ecuador Paragliding Guayaquil

Rp1.719.606
per adult
Ecuador Paragliding Guayaquil
See all activities in Guayaquil
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.