Lodging Image

Search Hotels in Siesta Isle, Fort Myers Beach

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Siesta Isle hotels

1. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
9.0 out of 10, Wonderful, (1,000 reviews)
"I like this hotel we have been twice"
United States
Giovanna
The price is Rp1.716.120
Rp1.913.519 total
includes taxes & fees
5 Nov - 6 Nov
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2. Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
2.6 km from Siesta Isle
9.0 out of 10, Wonderful, (2,733 reviews)
"Everything about the resort was excellent"
United States
Lance
The price is Rp3.251.740
Rp4.537.003 total
includes taxes & fees
29 Nov - 30 Nov
Margaritaville Beach Resort Fort Myers

3. Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
1.8 km from Siesta Isle
9.4 out of 10, Exceptional, (1,488 reviews)
"It's nice place to stay"
United States
Mario
The price is Rp3.905.356
Rp5.548.954 total
includes taxes & fees
15 Nov - 16 Nov
Pink Shell Beach Resort and Marina

4. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
2.7 km from Siesta Isle
9.2 out of 10, Wonderful, (1,004 reviews)
"Clean Hotel! Convenient for one night stay, close to airport and beaches."
United States
Kimberly
The price is Rp1.688.880
Rp1.883.102 total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

5. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
2.6 km from Siesta Isle
8.8 out of 10, Excellent, (1,006 reviews)
"One of the best properties I’ve stayed in and the staff were excellent."
United States
Christina
The price is Rp1.474.229
Rp1.643.765 total
includes taxes & fees
11 Nov - 12 Nov
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

6. Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
2.2 km from Siesta Isle
9.4 out of 10, Exceptional, (1,002 reviews)
"Convenient location, friendly staff and clean rooms."
United States
Stacy
The price is Rp3.934.182
Rp4.386.613 total
includes taxes & fees
18 Nov - 19 Nov
Best Western Plus Beach Resort

7. The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
2.4 km from Siesta Isle
8.6 out of 10, Excellent, (1,847 reviews)
"excellent place to stay"
United States
Shayne
The price is Rp1.462.769
Rp1.994.187 total
includes taxes & fees
16 Nov - 17 Nov
The Lighthouse Resort Inn & Suites

8. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
2.3 km from Siesta Isle
8.2 out of 10, Very good, (1,400 reviews)
"The staff was very helpful during my stay."
United States
Samantha
The price is Rp1.452.800
Rp1.619.872 total
includes taxes & fees
23 Nov - 24 Nov
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

9. DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
2.9 km from Siesta Isle
9.2 out of 10, Wonderful, (1,329 reviews)
"excellent place will stay again!"
United States
James Edward
The price is Rp3.636.148
Rp4.762.999 total
includes taxes & fees
3 Dec - 4 Dec
DiamondHead Beach Resort

10. Edison Beach House

Edison Beach House
3.5 star property
2.3 km from Siesta Isle
9.4 out of 10, Exceptional, (1,958 reviews)
"One of the best locations on Ft Myers Beach"
United States
mark
The price is Rp3.007.296
Rp4.061.829 total
includes taxes & fees
9 Nov - 10 Nov
Edison Beach House

11. Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
2.7 km from Siesta Isle
8.8 out of 10, Excellent, (2,174 reviews)
"It was great to be right on the beach! The restaurants were also good."
United States
Tanya
The price is Rp2.347.816
Rp3.022.783 total
includes taxes & fees
3 Dec - 4 Dec
Lani Kai Beachfront Resort

12. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
2.7 km from Siesta Isle
8.8 out of 10, Excellent, (1,001 reviews)
"Loved the balcony view, breakfast spread, hot tub and heated pool."
United States
Lora
The price is Rp1.779.680
Rp1.984.343 total
includes taxes & fees
22 Nov - 23 Nov
Residence Inn by Marriott Fort Myers Sanibel

13. Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
1.1 km from Siesta Isle
8.6 out of 10, Excellent, (1,002 reviews)
"Great place to stay, especially on a fishing trip!"
United States
Mitchel
The price is Rp1.616.051
Rp1.801.897 total
includes taxes & fees
5 Nov - 6 Nov
Latitude 26 Waterfront Resort & Marina

14. Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina
3.0 star property
2.1 km from Siesta Isle
9.4 out of 10, Exceptional, (1,000 reviews)
"I love Matanza. It's in a great location, walking distance to everything. I enjoyed sitting on the canal/bay and seeing all the wildlife, especially Manatee! We stayed in the 2 bedroom and it was perfect!"
United States
Tammy
The price is Rp5.066.640
Rp6.103.304 total
includes taxes & fees
5 Nov - 6 Nov
Matanzas Inn Bayside Resort and Marina

15. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
5.7 km from Siesta Isle
8.6 out of 10, Excellent, (1,001 reviews)
"I love everything about this hotel"
United States
Yunior
The price is Rp3.762.752
Rp4.831.069 total
includes taxes & fees
18 Nov - 19 Nov
Marriott Sanibel Harbour Resort & Spa

16. The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
2.7 km from Siesta Isle
7.8 out of 10, Good, (539 reviews)
"Clean room, helpful staff, very close to the beach."
United States
Andrea
The price is Rp1.944.508
Rp2.573.006 total
includes taxes & fees
5 Nov - 6 Nov
The Bay Inn at Lani Kai

17. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
9.7 km from Siesta Isle
9.4 out of 10, Exceptional, (1,744 reviews)
"Very clean - nice breakfast - great parking"
United States
Sherri
The price is Rp1.815.600
Rp2.024.394 total
includes taxes & fees
10 Nov - 11 Nov
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

18. Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
4.9 km from Siesta Isle
7.6 out of 10, Good, (1,000 reviews)
"I was satisfied with the price for a short stay."
United States
James
The price is Rp1.343.544
Rp1.498.051 total
includes taxes & fees
29 Nov - 30 Nov
Candlewood Suites Fort Myers Sanibel Gateway by IHG

19. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
8.3 km from Siesta Isle
9.0 out of 10, Wonderful, (1,000 reviews)
"Very clean and nice place!"
United States
Charles
The price is Rp2.655.860
Rp3.771.041 total
includes taxes & fees
29 Nov - 30 Nov
The Westin Cape Coral Resort At Marina Village

20. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
10.1 km from Siesta Isle
9.2 out of 10, Wonderful, (2,403 reviews)
"It was a wonderful stay. We really enjoyed it."
United States
Elina
The price is Rp3.613.044
Rp4.534.733 total
includes taxes & fees
9 Nov - 10 Nov
Sanibel Island Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Siesta Isle

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
9.0
Wonderful
1,000 reviews
View
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.
Pink Shell Beach Resort and Marina
4.0 star property
9.4
Exceptional
1,488 reviews
View
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
9.2
Wonderful
1,004 reviews
View
A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.
Best Western Plus Beach Resort
2.5 star property
9.4
Exceptional
1,002 reviews
View
A large, clear swimming pool with multiple lounge areas and palm trees.
Margaritaville Beach Resort Fort Myers
4.0 star property
9.0
Wonderful
2,733 reviews
View

Where to stay in Siesta Isle

Find the best Siesta Isle areas for the activities you enjoy most.

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

South Island

While visiting South Island, you might make a stop by sights like Santini Marina Shopping Plaza and Castle Beach.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

Winklers

Winklers might not have many top sights, but Key West Express and Estero Boulevard Beach are two attractions nearby that you can check out.

Top Siesta Isle Hotel Reviews

Frequently asked questions

What is Siesta Isle like?
Travellers will be sure to find plenty to entertain them in Fort Myers Beach's Siesta Isle neighbourhood. Consider a visit to San Carlos Bay - Bunche Beach Preserve as part of your Siesta Isle travel plans.
Where is the best place to stay in Siesta Isle?
Based on our traveller data, Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is one of the top choices for your stay in Siesta Isle. This hotel offers a marina and free breakfast.
How many hotels will I find in the Siesta Isle area?
If you're searching for places to stay in Fort Myers Beach, Expedia has something to meet your needs with 27 Siesta Isle hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Siesta Isle, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the best deals in Siesta Isle.
What are the top things to see and do in Siesta Isle?
San Carlos Bay - Bunche Beach Preserve is an attraction you might want to check out while you're in Siesta Isle. Key West Express and Bunche Beach are also worth a visit when you're out sightseeing in Fort Myers Beach.