Southeast Massachusetts featuring a river or creek, fishing and autumn colours

Southeast Massachusetts hotel guide. La Quinta Inn & Suites hotel in Southeast Massachusetts, United States of America

Change your mind

Book hotels with free cancellation

Treat yourself

Sign in to save 10% or more on thousands of hotels

Sign in

Be picky

Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Top Southeast Massachusetts La Quinta Inn & Suites Hotels

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Southeast Massachusetts Hotel Reviews

5/5 Excellent

"Great spot and super convenient for beach and sightseeing in general!! You’ll love the sunsets too!"

A verified traveller stayed at Red Jacket Beach Resort

Posted 3 days ago

5/5 Excellent

The Best Hotel in Falmouth

"I had such a wonderful stay at the Iris Hotel Cape Cod! The location is truly ideal: just a short drive from the beach and the ferry, and only minutes away from downtown Falmouth. There are plenty of great dining options nearby within walking distance, including a cozy local favorite, Jack’s Restaurant. And if you’re staying in for the night, Jones Tavern is right inside the hotel — the perfect spot to grab a drink or a bite without going far. I’ll definitely be coming back!"

A verified traveller stayed at Iris Hotel Cape Cod

Posted 6 days ago

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Search Southeast Massachusetts Hotel Brands

Areas of Southeast Massachusetts

Hotels near popular Southeast Massachusetts Attractions

Hotels near Mayflower Beach

Hotel Deals in Other Destinations

Explore more hotels

See a list of all hotels in Southeast Massachusetts

More ways to book

Book La Quinta Inn & Suites in Southeast Massachusetts on Expedia.com

Members save 10% or more on over 100,000 hotels worldwide when you’re signed in