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Our top choices for Southwest Coast Florida hotels

A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

1. Best Western Fort Myers Inn & Suites

Fort Myers

Azael

Rp1.540.845 total

includes taxes & fees

15 Nov - 16 Nov

A modern hotel lobby with a reception desk, seating area, and a dining section.

2. Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor

Brian

Rp2.034.052 total

includes taxes & fees

15 Nov - 16 Nov

A Drury Inn & Suites hotel with a parking lot full of cars.

3. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes

Giselia Dos Santos

Rp2.396.355 total

includes taxes & fees

1 Dec - 2 Dec

A large, clear swimming pool with multiple lounge areas and palm trees.

4. Margaritaville Beach Resort Fort Myers

Fort Myers Beach

Lance

Rp4.513.269 total

includes taxes & fees

29 Nov - 30 Nov

A modern kitchen with a breakfast bar, various food items, and a chalkboard menu.

5. Hampton Inn & Suites Fort Myers - Colonial Blvd

Fort Myers

Luis

Rp2.037.073 total

includes taxes & fees

22 Nov - 23 Nov

A modern kitchen area with a breakfast bar, fruit display, and a chalkboard menu.

6. Hampton Inn Fort Myers Downtown

Fort Myers River District

Donald

Rp2.130.316 total

includes taxes & fees

23 Nov - 24 Nov

An outdoor patio area with round tables and chairs, ceiling fans, and a bar area with shelves of bottles.

7. Doubletree by Hilton Fort Myers at Bell Tower Shops

Villas

James

Rp2.208.255 total

includes taxes & fees

23 Nov - 24 Nov

A Comfort Inn & Suites hotel with a covered entrance, palm trees, and a well-lit facade.

8. Comfort Inn & Suites Fort Myers Airport

Daniels Corridor

Frank

Rp1.504.392 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with a bed, a desk, a chair, and a small table.

9. SpringHill Suites by Marriott Fort Myers Airport

Daniels Corridor

Jon B.

Rp1.780.300 total

includes taxes & fees

29 Nov - 30 Nov

An outdoor patio with a barbecue area, seating, and string lights.

10. Homewood Suites by Hilton Fort Myers Airport/FGCU

Miromar Lakes

Leo

Rp2.482.148 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with a staircase, seating area, and a large wall-mounted screen.

11. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Daniels Corridor

Merlin

Rp1.323.140 total

includes taxes & fees

12 Nov - 13 Nov

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

Sherri

Rp2.034.052 total

includes taxes & fees

17 Nov - 18 Nov

A reception area with a modern design, featuring a wooden panel wall with integrated lighting, a reception desk, and a refrigerator stocked with beverages.

13. Comfort Suites Fort Myers East I-75

Fort Myers

Eloan

Rp1.888.647 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio with a fire pit, green chairs, a red umbrella, and a bar area.

14. Home2 Suites by Hilton Fort Myers Colonial Blvd

Fort Myers

Paul

Rp2.447.912 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

15. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor

Bruce

Rp1.728.945 total

includes taxes & fees

22 Nov - 23 Nov

A multi-level hotel atrium with balconies, seating areas, and a central courtyard.

16. Embassy Suites by Hilton Fort Myers Estero

Estero

Robert

Rp2.496.044 total

includes taxes & fees

17 Nov - 18 Nov

17. Quality Inn & Suites Lehigh Acres Fort Myers

Lehigh Acres

Exia

Rp1.196.264 total

includes taxes & fees

22 Nov - 23 Nov

A reception area with a modern design, featuring a reception desk, a wall-mounted information board, and a refrigerator stocked with beverages.

18. MainStay Suites Fort Myers East I-75

Fort Myers

Marcellus

Rp2.054.191 total

includes taxes & fees

29 Nov - 30 Nov

An outdoor patio area with a stone fire pit, seating, and string lights.

19. SpringHill Suites by Marriott Fort Myers Estero

Estero

Nail

Rp2.519.405 total

includes taxes & fees

16 Nov - 17 Nov

20. HomeTowne Studios by Red Roof Fort Myers

Fort Myers

Ashley

Rp1.305.017 total

includes taxes & fees

15 Nov - 16 Nov

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Holiday Rentals in Southwest Coast Florida

Aparthotel

A balcony with a TV, a chair, and a view of a beach with a pier.

Edison Beach House

Fort Myers Beach

"Best place ever"

Aparthotel

A beach with a thatched-roof structure, palm trees, and a view of the sea.

The Suites at Fishermen’s Village

Punta Gorda Isles

"Great place to stay but comes with a price."

Apartment

A swimming pool with lounge chairs and a building with a sloped roof in the background.

Landing Apartments Fort Myers near Eastwood Village

Fort Myers

"Amazing , safe and beautiful place to stay . I was there for over 3 weeks and it’s local to many great locations , quiet and safe and over all highly recommend."

Aparthotel

A modern hotel room with a kitchenette, a bed, a seating area, and a wardrobe.

StudioRes by Marriott Fort Myers Airport

Fort Myers

"Location was great."

Aparthotel

A beach with a clear sky, a palm tree, and a sandy path leading to the water.

Sanibel Siesta on the Beach

Mid Island

"Great location and close to beach. Rooms nice and it had everything you needed for the beach. Pool wonderful"

Apartment

A spacious living area with a curved ceiling, large windows, a dining area, and a kitchen.

Landing Furnished Apartments minutes from Downtown Fort Myers

Hancock

"Clean, quiet, perfect alternative to a hotel"

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Stay near popular Southwest Coast Florida attractions

A lifeguard tower with an American flag, a green flag, and a signboard on a beach with people sunbathing and umbrellas.

Siesta Key Beach

9.6/10 (4,113 reviews)

The soft, white sand on Siesta Key’s award-winning family-friendly beach is perfect for relaxing under a sun umbrella and taking part in a game of volleyball.

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Learn more about Southwest Coast Florida

Amazing beaches, island views and top sights from Key West Express to Siesta Key Beach—discover Southwest Coast Florida, a destination also famous for its live music scene.

See all hotels in Southwest Coast Florida

A sunset over a beach with a pier and people walking on the sand.

Top Southwest Coast Florida Hotel Reviews

The Lighthouse Resort Inn & Suites

10/10 Excellent

"My wife and I recently stayed at the Lighthouse Inn, and we really enjoyed our stay! We especially appreciated the covered parking, the cleanliness and our junior suite was very nice with a huge private deck. The location is fantastic, just a couple of minutes’ walk to everything. The tiki bar is great, and the pool area is very nice as well. Overall, we had a wonderful experience and will definitely be staying here again!"

Hyatt Vacation Club at Coconut Cove, Bonita Springs

8/10 Good

"The property was pretty and clean but the amenities were just ok. Lazy river is lovely and pools had nice temp. But the tiny market only open until 12:30 and that’s the only place to get coffee and the machine was broken, so no coffee. Could use a nice restaurant- only have a tiki hut filled with bees for food."