Southwest Illinois Holiday Rentals, Illinois: Private House Rentals

A calm lake surrounded by trees and vegetation.

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Our top choices for Southwest Illinois hotels

A bar area with a long counter, multiple chairs, and hanging light fixtures.

An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.

A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.

1. Drury Plaza Hotel Mt. Vernon

Mount Vernon

Kirstyn

Rp1.987.054

Rp2.241.039 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a bed, bedside table, chair, and artwork on the walls.

A clean, modern breakfast area with a bakery section, a hot food station, and a sign indicating breakfast is ready when you are.

A hotel room with a blue sofa, a bed with white bedding, a nightstand, a desk with a chair, and a large window offering a view.

A coffee station with two coffee machines and a variety of coffee pods and cups.

2. Holiday Inn Express & Suites Vandalia by IHG

Vandalia

Scott

Rp2.184.166

Rp2.380.383 total

includes taxes & fees

18 Oct - 19 Oct

A hotel lobby with a reception desk, seating area, and a large screen TV.

A brick building with a patio area featuring wicker furniture and a table.

A hotel dining area with a large wooden table, red upholstered chairs, a flat-screen TV mounted above the fireplace, and a kitchen area in the background.

A hotel room with a marble bathtub, a wooden dining table with chairs, a bed with a headboard, and a nightstand with lamps.

3. Comfort Suites Mount Vernon

Mount Vernon

Lori

Rp2.105.487

Rp2.372.476 total

includes taxes & fees

18 Oct - 19 Oct

A brick building with a wooden gazebo in front.

A statue of a Native American figure with a horse, a Route 66 sign, a map, and a clock on the wall.

A compact kitchen with a sink, microwave, and stove, a wooden cabinet, and a television mounted on the wall.

A spacious dining area with multiple round tables and chairs, a fireplace, and large windows with curtains.

4. Country Hearth Inn & Suites Edwardsville St. Louis

Edwardsville

Kristy

Rp2.309.487

Rp2.655.373 total

includes taxes & fees

30 Sept - 1 Oct

A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.

A Country Inn & Suites building with a covered entrance and a parking lot.

An indoor swimming pool with clear water, surrounded by white lounge chairs and tables, with a high ceiling and natural light from windows.

A modern living room with a sofa, coffee table, and a dining area with chairs.

5. Country Inn & Suites by Radisson, Marion, IL

Marion

Lisa

Rp1.646.785

Rp1.975.812 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A breakfast area with a Superstart breakfast sign, a coffee machine, a refrigerator, and a bowl of fruit on the counter.

A parking lot with a Super 8 sign, a white car, and a truck.

A hotel with a brick facade, a flagpole with an American flag, and a parking lot with several cars.

6. Super 8 by Wyndham Mt. Vernon IL

Mount Vernon

Devin

Rp1.306.919

Rp1.486.225 total

includes taxes & fees

11 Oct - 12 Oct

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows offering views of the outside.

A hotel room with a bed, a desk, a chair, and a small table.

A Best Western hotel with a large sign, multiple parking spaces, and a well-lit entrance.

A hotel room with a Samsung monitor displaying a hotel booking site, a smaller monitor, a keyboard, a mouse, and a printer.

7. Best Western Troy Hotel

Troy

joshua

Rp1.772.397

Rp1.967.003 total

includes taxes & fees

30 Sept - 1 Oct

A lobby with a wooden staircase, a desk with a computer, and patterned armchairs.

A hotel room with a large bed, two bedside tables, a nightstand, and a lamp on each side.

A Ramada hotel with a brick facade, large entrance, and a clear sky.

A kitchen with white cabinets, a microwave, a coffee machine, and a refrigerator.

8. Ramada by Wyndham Vandalia

Vandalia

Samantha

Rp1.450.143

Rp1.580.298 total

includes taxes & fees

11 Oct - 12 Oct

A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

A hotel room with two beds, a large window with curtains, a wall-mounted lamp, and a patterned carpet.

A modern kitchen with a checkered tile backsplash, wooden flooring, and stainless steel appliances.

A spacious lobby with a large seating area, a reception desk, and a television.

9. Best Western Plus Centralia Hotel & Suites

Centralia

Corey

Rp2.488.517

Rp2.786.602 total

includes taxes & fees

7 Oct - 8 Oct

A restaurant with multiple tables and booths, large windows, and a modern interior design.

A neatly made bed with white linens and a dark headboard, flanked by two bedside tables with lamps.

A modern kitchen with a central island, bar stools, and a dining area.

A wooden wall with the sign "THE PRINCIPAL HOTEL" and a row of books below.

10. The Principal Hotel

Columbia

Kenny

Rp1.756.284

Rp1.949.125 total

includes taxes & fees

30 Sept - 1 Oct

An indoor swimming pool area with multiple lanes, lounge chairs, and a small seating area.

A modern hotel lobby with seating areas, including sofas and chairs, and a large window with blinds.

A lobby with two armchairs, a lamp, a framed artwork, and a sign indicating a fitness center.

A lobby with patterned sofas, a fireplace, and framed pictures on the wall.

11. Drury Inn & Suites St. Louis O'Fallon, IL

O'Fallon

KEVIN

Rp1.825.927

Rp2.117.710 total

includes taxes & fees

12 Oct - 13 Oct

A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and illuminated pillars.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a window providing natural light.

A buffet with labeled food options including turkey sausage and bacon.

A hotel room with two beds, a large window, and a wall-mounted lamp.

12. Holiday Inn Express & Suites Mount Vernon by IHG

Mount Vernon

John

Rp2.112.554

Rp2.380.319 total

includes taxes & fees

9 Oct - 10 Oct

A modern living room with a fireplace, blue sofa, red chairs, and a flat-screen TV mounted on a textured wall.

A hotel reception area with a long wooden counter, coffee machines, and a wall with framed pictures.

A hotel reception area with a computer desk, a printer, a coffee machine, and a framed cityscape picture on the wall.

13. Comfort Inn & Suites Greenville I-70

Greenville

Debbie

Rp1.776.515

Rp1.971.576 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

A laundry area with two washers and dryers, a coin-operated machine, and a sign indicating the coin slot locks out when empty.

A hotel with a covered entrance, multiple rooms, and a parking lot.

A hotel room with two beds, a nightstand, a lamp, and a framed picture on the wall.

14. Quality Inn Mount Vernon, IL

Mount Vernon

Matthew

Rp1.353.467

Rp1.537.883 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a bed, a desk with a chair, a sofa, and a small table.

A hotel reception area with a reception desk, a clock, a television, and a seating area with an orange chair and a table.

A hotel lobby with a reception desk, seating area, and a TV mounted on the wall.

A modern living room with a flat-screen TV, a small kitchen with wooden cabinets, a dining area with two chairs, and a staircase leading to an upper level.

15. Quality Inn & Suites Vandalia near I-70 and Hwy 51

Vandalia

Cherilyn

Rp1.301.906

Rp1.418.817 total

includes taxes & fees

27 Oct - 28 Oct

A hotel room with two beds, a desk with a computer, a chair, a TV, and two wall-mounted lamps.

A bathroom with a granite countertop sink, a mirror, a towel rack, and a telephone.

A reception area with a counter, framed certificates, a clock, and a checkered floor.

A conference room with a TV, a door, and a window with blinds.

16. Super 8 by Wyndham Okawville

Okawville

Peter

Rp1.126.278

Rp1.193.629 total

includes taxes & fees

19 Oct - 20 Oct

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.

A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.

A compact kitchenette with a refrigerator and an ice dispenser.

A reception area with a stone wall, a round mirror, a reception desk, and a computer setup.

17. Best Western U. S. Inn

Nashville

Arilla

Rp2.148.181

Rp2.341.175 total

includes taxes & fees

30 Sept - 1 Oct

An outdoor patio with tables and chairs, a brick building, and a parking lot in the background.

A reception area with a wooden reception desk, a wall-mounted decorative piece, and a vending machine.

A modern living room with a fireplace, comfortable seating, and a television.

A gym with weightlifting equipment, treadmills, and a mirrored wall.

18. Fairfield Inn & Suites by Marriott O'Fallon, IL

O'Fallon

Mohamad

Rp2.267.415

Rp2.607.073 total

includes taxes & fees

4 Oct - 5 Oct

A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.

A spacious lobby with a stone reception desk, leather seating, and a large window offering a view of the outdoors.

A modern hotel room with a living area, a kitchenette, and a door leading to another room.

A hotel room with a large bed, a desk with a chair, a sofa, and a TV.

19. Best Western Plus MidAmerica Hotel

Mascoutah

Danny

Rp1.961.274

Rp2.235.401 total

includes taxes & fees

4 Oct - 5 Oct

A small, clean room with a microwave, a vending machine, and a table with chairs.

A bathroom with a shower, a bathtub, and a toilet.

A self-service laundry station with multiple washing machines, a price tag of $1.50, and a sign indicating guest services at the lobby.

A reception area with a wooden counter, a tiled floor, and a wall with framed pictures.

20. Rodeway Inn Mount Vernon, IL

Mount Vernon

Emil

Rp1.217.404

Rp1.386.882 total

includes taxes & fees

30 Sept - 1 Oct

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Stay near popular Southwest Illinois attractions

World Wide Technology Raceway

9.0/10 (2 reviews)

Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

See properties

O'Fallon Family Sports Park

8.6/10 (137 reviews)

Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Visit the shops and top-notch restaurants in this family-friendly area.

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DuQuoin State Fairgrounds

8.2/10 (95 reviews)

Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.

See properties

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois

A tall, modern tower with balconies, set against a clear blue sky.

Top Southwest Illinois Hotel Reviews

Drury Inn & Suites St. Louis Collinsville

10/10 Excellent

"Great stay and the evening reception and morning breakfast offered many options."

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

8/10 Good

"It was a quick only one night stop for us during our cross-country trip. It was okay, I say it is definitely budget friendly. Shower power was weak. Clean and comfortable for us! It was close enough driving distance to visit Gateway arch National Park in MO."

Baymont by Wyndham Marion

8/10 Good

"The only thing that I think would be good to change is to add something so the bath tubs are not so slippery."

Comfort Inn Edwardsville - St. Louis

10/10 Excellent

"Property was well maintained. The room was clean and the bed was comfortable. The shower looked a little worn in some spots but it was fine overall. Room was cool and you could control the temperature. The breakfast was great and a nice touch every morning. Food was fresh and hot. Staff was friendly. We came for family weekend and we would stay again."

Walker's Bluff Casino Resort

10/10 Excellent

"The staff were very kind and helpful! The security guard even noticed my trunk was opened and closed it for me. I’ve stayed twice and both times the hotel and room was very clean and staff were friendly and welcoming. My only two complaints would be that the music in the lobby is loud and annoying and that the breakfast isn’t worth the price. But those things won’t keep from staying again when I’m in the area. I think the hotel clerk was Miranda in the evening and she was above and beyond friendly!"

Radisson Hotel Fairview Heights - St. Louis

8/10 Good

"Our stay at the Radisson was good overall and the prices are good . The location was convenient to restaurants and shopping .The first room had a wet carpet smell and the front desk was notified and immediately moved us to another room . The bed was comfortable, the bar inside was nice and reasonably priced. The property was clean and everyone was friendly . My only complaint would be our towels had stains on them and the room had minor spots and stains in certain areas but overall the stay was nice and we would definitely stay again ."

Country Inn & Suites by Radisson, Fairview Heights, IL

10/10 Excellent

"Was perfect for our plans. Hotel was clean with friendly staff."

More cheap stays in Southwest Illinois

Americas Best Value Inn Collinsville St. Louis

552 Ramada Blvd Collinsville IL

Rp942.235

Rp1.083.490 total

11 Oct - 12 Oct

includes taxes & fees

6.4/10 (977 reviews)

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

Rp958.706

Rp1.102.320 total

21 Oct - 22 Oct

includes taxes & fees

6.6/10 (1,115 reviews)

Super 8 by Wyndham Collinsville St. Louis

2 Gateway Dr Collinsville IL

Rp1.283.629

Rp1.475.917 total

5 Oct - 6 Oct

includes taxes & fees

7/10 Good! (1,003 reviews)

Best Western St. Louis Fairview Heights

150 Ludwig Dr Fairview Heights IL

Rp1.506.537

Rp1.702.086 total

1 Oct - 2 Oct

includes taxes & fees

7.4/10 Good! (124 reviews)

Comfort Inn Edwardsville - St. Louis

3080 S State Route 157 Edwardsville IL

Rp1.704.366

Rp1.959.680 total

18 Oct - 19 Oct

includes taxes & fees

8.4/10 Very good! (955 reviews)

Baymont by Wyndham Marion

2608 W Main St Marion IL

Rp1.724.989

Rp2.069.641 total

25 Oct - 26 Oct

includes taxes & fees

8.4/10 Very good! (1,095 reviews)

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Book Hotels in Southwest Illinois on Expedia.com

Find hotels in Southwest Illinois, IL from Rp1.083.490

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southwest Illinois

Check prices for these dates

Filter by

Star rating

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Our top choices for Southwest Illinois hotels

1. Drury Plaza Hotel Mt. Vernon

2. Holiday Inn Express & Suites Vandalia by IHG

3. Comfort Suites Mount Vernon

4. Country Hearth Inn & Suites Edwardsville St. Louis

5. Country Inn & Suites by Radisson, Marion, IL

6. Super 8 by Wyndham Mt. Vernon IL

7. Best Western Troy Hotel

8. Ramada by Wyndham Vandalia

9. Best Western Plus Centralia Hotel & Suites

10. The Principal Hotel

11. Drury Inn & Suites St. Louis O'Fallon, IL

12. Holiday Inn Express & Suites Mount Vernon by IHG

13. Comfort Inn & Suites Greenville I-70

14. Quality Inn Mount Vernon, IL

15. Quality Inn & Suites Vandalia near I-70 and Hwy 51

16. Super 8 by Wyndham Okawville

17. Best Western U. S. Inn

18. Fairfield Inn & Suites by Marriott O'Fallon, IL

19. Best Western Plus MidAmerica Hotel

20. Rodeway Inn Mount Vernon, IL

Stay near popular Southwest Illinois attractions

World Wide Technology Raceway

O'Fallon Family Sports Park

DuQuoin State Fairgrounds

Learn more about Southwest Illinois

Top Southwest Illinois Hotel Reviews

Drury Inn & Suites St. Louis Collinsville

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Baymont by Wyndham Marion

Comfort Inn Edwardsville - St. Louis

Walker's Bluff Casino Resort

Radisson Hotel Fairview Heights - St. Louis

Country Inn & Suites by Radisson, Fairview Heights, IL

More cheap stays in Southwest Illinois

Americas Best Value Inn Collinsville St. Louis

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham Collinsville St. Louis

Best Western St. Louis Fairview Heights

Comfort Inn Edwardsville - St. Louis

Baymont by Wyndham Marion

Explore a world of travel with Expedia

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