Search Hotels in St. Charles Historic District, St. Louis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
8 Nov - 9 Nov
Tomorrow
9 Nov - 10 Nov
Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for St. Charles Historic District hotels

A brick building with a sign reading "Country Inn & Suites."

1. Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1,112 reviews)
"Very convenient to downtown St Charles. As per previous visits this hotel is excellent for the price range of the rooms."
United States
Stewart
The price is Rp2.294.771
Rp2.637.311 total
includes taxes & fees
6 Dec - 7 Dec
Country Inn & Suites by Radisson, St. Charles Historic District
A large hotel with a prominent tower and multiple parking areas.

2. Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
3.3 km from St. Charles Historic District
8.6 out of 10, Excellent, (2,249 reviews)
"Always love staying here! Rooms are so spacious and comfy"
United States
Shayla
The price is Rp1.251.643
Rp1.733.472 total
includes taxes & fees
6 Dec - 7 Dec
Hollywood Casino & Hotel St. Louis
A multi-level hotel lobby with numerous seating areas, a central water feature, and a variety of plants.

3. Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
1.9 km from St. Charles Historic District
8.8 out of 10, Excellent, (1,002 reviews)
"Great place to stay"
United States
Elyse
The price is Rp2.358.444
Rp2.710.488 total
includes taxes & fees
22 Nov - 23 Nov
Embassy Suites by Hilton St. Louis St. Charles
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

4. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
1.6 km from St. Charles Historic District
8.6 out of 10, Excellent, (1,093 reviews)
"Very nice hotel, lots of amenities, and restaurants"
United States
Carter
The price is Rp2.879.769
Rp3.665.696 total
includes taxes & fees
22 Nov - 23 Nov
Ameristar Casino Resort and Spa
A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

5. Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
1.5 km from St. Charles Historic District
8.4 out of 10, Very good, (1,005 reviews)
"Great stay."
United States
Bryan
The price is Rp1.669.796
Rp1.919.046 total
includes taxes & fees
22 Nov - 23 Nov
Comfort Suites St Charles - St Louis
A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

6. Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
1.8 km from St. Charles Historic District
9.6 out of 10, Exceptional, (1,006 reviews)
"I enjoyed my stay"
United States
Madhusudhana Rao
The price is Rp2.622.724
Rp3.040.446 total
includes taxes & fees
15 Nov - 16 Nov
Drury Plaza Hotel St. Louis St. Charles
A modern meeting room with a long table, comfortable seating, and a brick wall backdrop.

7. Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
1.6 km from St. Charles Historic District
9.0 out of 10, Wonderful, (762 reviews)
"Great stay!"
United States
Sara
The price is Rp2.167.967
Rp2.603.702 total
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn & Suites St. Charles Old Town Area
A modern hotel with a prominent Hilton logo, multiple floors, and a well-lit entrance.

8. Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
2 km from St. Charles Historic District
8.6 out of 10, Excellent, (890 reviews)
"Nice relaxing place"
United States
Michael
The price is Rp2.290.972
Rp2.655.856 total
includes taxes & fees
22 Nov - 23 Nov
Tru by Hilton St. Charles St. Louis, MO
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

9. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
11.3 km from St. Charles Historic District
9.2 out of 10, Wonderful, (1,735 reviews)
"Near the airport; good breakfast."
United States
Cindy
The price is Rp1.814.688
Rp2.154.725 total
includes taxes & fees
15 Nov - 16 Nov
Wingate by Wyndham St. Louis Airport
A modern hotel lobby with a reception desk, seating area, and a large painting on the wall.

10. Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG
3.5 star property
3.4 km from St. Charles Historic District
7.6 out of 10, Good, (1,000 reviews)
"It was clean and have no complaints."
United States
Vincent
The price is Rp1.362.644
Rp1.580.503 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn St. Louis Arpt West-Earth City by IHG
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

11. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
11.2 km from St. Charles Historic District
9.4 out of 10, Exceptional, (3,362 reviews)
"Great stay for airport access"
United States
Rebecca
The price is Rp1.627.829
Rp1.932.851 total
includes taxes & fees
12 Nov - 13 Nov
Pear Tree Inn St. Louis Airport
A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

12. Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
11.9 km from St. Charles Historic District
9.2 out of 10, Wonderful, (1,460 reviews)
"Excellent place to stay, highly recommend."
United States
Ethan
The price is Rp2.080.054
Rp2.461.495 total
includes taxes & fees
15 Nov - 16 Nov
Drury Inn & Suites St. Louis Airport
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

13. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
12.6 km from St. Charles Historic District
9.2 out of 10, Wonderful, (1,017 reviews)
"Loved my stay"
United States
Thadora
The price is Rp1.983.459
Rp2.459.210 total
includes taxes & fees
10 Nov - 11 Nov
Hyatt Select St. Louis Airport
The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

14. The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
21.2 km from St. Charles Historic District
9.4 out of 10, Exceptional, (722 reviews)
"We will absolutely stay here again when traveling to Wash U. Great hotel!"
United States
jeffrey
The price is Rp2.477.108
Rp2.848.377 total
includes taxes & fees
24 Nov - 25 Nov
The Knight Center at Washington University
A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

15. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
13.5 km from St. Charles Historic District
8.4 out of 10, Very good, (1,197 reviews)
"Great Hotel."
United States
Joy
The price is Rp2.011.497
Rp2.353.210 total
includes taxes & fees
21 Nov - 22 Nov
Renaissance St. Louis Airport Hotel
A modern lounge area with a curved seating arrangement, a central coffee table, and a kitchen in the background.

16. SpringHill Suites by Marriott St. Louis Airport/Earth City

SpringHill Suites by Marriott St. Louis Airport/Earth City
3.0 star property
4.8 km from St. Charles Historic District
8.8 out of 10, Excellent, (1,000 reviews)
"Clean room."
United States
Tiffany
The price is Rp2.212.646
Rp2.648.329 total
includes taxes & fees
15 Nov - 16 Nov
SpringHill Suites by Marriott St. Louis Airport/Earth City
Exterior

17. Elimwood Hotel, a Ramada by Wyndham

Elimwood Hotel, a Ramada by Wyndham
3.0 star property
3.5 km from St. Charles Historic District
7.6 out of 10, Good, (1,006 reviews)
"Nothing special breakfast was good and the little water feature is cool to sit by."
United States
Lucas
The price is Rp1.277.118
Rp1.494.075 total
includes taxes & fees
15 Nov - 16 Nov
Elimwood Hotel, a Ramada by Wyndham
A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a door, and a wall with a road map mural.

18. Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
4.1 km from St. Charles Historic District
8.2 out of 10, Very good, (1,003 reviews)
"Clean room, staff was polite and helpful!"
United States
Tammie
The price is Rp1.414.560
Rp1.625.711 total
includes taxes & fees
6 Dec - 7 Dec
Super 8 by Wyndham St Charles
An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

19. Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport
2.5 star property
12.3 km from St. Charles Historic District
9.0 out of 10, Wonderful, (257 reviews)
"Loved that the Hampton and Hilton were connected and we were able to relax without having to leave to find somewhere to eat."
United States
Janet
The price is Rp2.063.593
Rp2.483.288 total
includes taxes & fees
19 Nov - 20 Nov
Hampton Inn By Hilton St Louis Airport
A brick building with a tower, large windows, and a fountain in the garden.

20. Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
18 km from St. Charles Historic District
8.8 out of 10, Excellent, (1,001 reviews)
"Very pleasant staff. Nice breakfast. Clean rooms."
United States
Karen
The price is Rp2.358.444
Rp2.747.304 total
includes taxes & fees
29 Nov - 30 Nov
Hilton St. Louis Frontenac
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in St. Charles Historic District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A brick building with a sign reading "Country Inn & Suites."
Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
9.4
Exceptional
1,112 reviews
View
A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.
Drury Plaza Hotel St. Louis St. Charles
3.0 star property
9.6
Exceptional
1,006 reviews
View
A modern meeting room with a long table, comfortable seating, and a brick wall backdrop.
Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
9.0
Wonderful
762 reviews
View
A multi-level hotel lobby with numerous seating areas, a central water feature, and a variety of plants.
Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
8.8
Excellent
1,002 reviews
View
A modern hotel with a prominent Hilton logo, multiple floors, and a well-lit entrance.
Tru by Hilton St. Charles St. Louis, MO
2.5 star property
8.6
Excellent
890 reviews
View

Where to stay in St. Charles Historic District

Find the best St. Charles Historic District areas for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

A large airplane suspended in a net structure in an urban setting with modern buildings in the background.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Top St. Charles Historic District Hotel Reviews

A large hotel with a prominent tower and multiple parking areas.
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
Riverport

10/10 Excellent

Perfect for concerts, shuttle all the way
United Kingdom
Katrina
Reviewed July 28, 2026
Hollywood Casino & Hotel St. Louis

Frequently Asked Questions

What's it like in St. Charles Historic District?

St. Charles Historic District is an historic neighbourhood known for its array of dining options and major shopping area. Are you looking for St. Charles Historic District travel tips? Make sure that you visit Historic Main Street and Missouri River while you're in the neighbourhood.

Where is the best hotel for a stay in St. Charles Historic District?

Based on our traveller data, Country Inn & Suites by Radisson, St. Charles Historic District is one of the top choices for your stay in St. Charles Historic District. This hotel is a short 8-minute walk from Ameristar Casino St. Charles, and it offers free breakfast and an indoor pool.

How many hotels will I be able to find in the St. Charles Historic District area?

Expedia has 95 hotels and other accommodation options in St. Charles Historic District to choose from, making this an ideal home base for exploring the greater St. Charles area.

If I need to cancel my hotel reservation in St. Charles Historic District, will I receive a refund?

Yes, the majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view the top deals on offer in St. Charles Historic District.

What can I see and do in this St. Charles neighbourhood?

Explore St. Charles Historic District's landmarks such as Historic Main Street, First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center and learn about the local history. Missouri River and Frontier Park are also a couple of places to visit in the neighbourhood. Missouri Artists on Main, Frenchtown Heritage Museum and Ameristar Casino St. Charles are just a few of the places to visit in and around St. Charles Historic District. While you're out sightseeing, Katy Trail and St Charles Convention Center are a couple of additional sights to visit in St. Charles.