St. Charles Holiday Rentals, St. Louis: Private House Rentals

A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

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Our top choices for St. Charles hotels

A brick building with a sign reading "Country Inn & Suites."

A spacious living room with a blue sofa, a white coffee table, and a striped armchair. There is a bookshelf filled with decorative items and a television on a wooden stand.

A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

1. Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District

Stewart

Rp2.205.893

Rp2.535.167 total

includes taxes & fees

22 Nov - 23 Nov

A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

A bakery display case with various pastries and cakes.

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

2. Ameristar Casino Resort and Spa

St. Charles

Melissa

Rp2.869.102

Rp3.652.118 total

includes taxes & fees

16 Nov - 17 Nov

A white bed with pillows, one of which has a label that reads "Pure."

A hotel room with a sofa, a green ottoman, a dining table with chairs, a television, and a minibar.

A coffee shop interior with a display case of pastries and a menu board above it.

A spacious lobby with a patterned carpet, a staircase, and an elevator area.

3. Embassy Suites by Hilton St. Louis St. Charles

St. Charles

Elyse

Rp2.349.708

Rp2.700.448 total

includes taxes & fees

22 Nov - 23 Nov

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.

A spacious lobby with a large sectional sofa, a reception desk, and a bar area.

A gym with treadmills, stationary bikes, and a weight machine.

4. Drury Plaza Hotel St. Louis St. Charles

St. Charles

Robert

Rp2.608.660

Rp3.024.141 total

includes taxes & fees

1 Nov - 2 Nov

A modern meeting room with a long table, comfortable seating, and a brick wall backdrop.

A hotel room with a large bed, a desk, a chair, and a window with a view.

An indoor swimming pool with blue walls, a tiled floor, and lounge chairs.

A modern hotel reception area with a receptionist desk, a large welcome sign, and a view of the cityscape through the glass doors.

5. Hampton Inn & Suites St. Charles Old Town Area

St. Charles

Sara

Rp2.129.299

Rp2.558.542 total

includes taxes & fees

22 Nov - 23 Nov

A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

A lobby with a wooden floor, a reception desk, a seating area with a red sofa, and a glass door leading to another room.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A spacious lobby with a reception desk, a seating area with a sofa, a vending machine, and a wall-mounted clock.

6. Comfort Suites St Charles - St Louis

St. Charles

Bryan

Rp1.721.822

Rp1.978.838 total

includes taxes & fees

22 Nov - 23 Nov

A swimming pool area with red and white lounge chairs, a glass table, and a blue and yellow ceiling.

A hotel room with a bed, a desk with a TV, a lamp, and a nightstand.

A gym with treadmills, elliptical machines, and free weights.

A hotel lobby with multiple seating areas, including booths and tables, and a check-in counter in the background.

7. Hampton Inn St. Charles St. Peters

St. Charles

Catherine

Rp1.973.049

Rp2.267.708 total

includes taxes & fees

22 Nov - 23 Nov

A modern cafe with a self-serve beverage station, a central island with seating, and large windows offering a view.

A self-service beverage station with a refrigerated display and a microwave.

A modern lounge area with sofas, tables, and chairs, featuring a mix of seating arrangements and a central coffee station.

8. Tru by Hilton St. Charles St. Louis, MO

St. Charles

Kippi

Rp2.278.687

Rp2.641.613 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a door, and a wall with a road map mural.

A kitchenette with a coffee machine, a coffee dispenser, and a coffee maker.

An indoor swimming pool with clear water, surrounded by chairs and a covered area.

A reception area with a sliding glass door, a reception desk, and a window with plants.

9. Super 8 by Wyndham St Charles

St. Charles

Patrick

Rp1.437.561

Rp1.652.145 total

includes taxes & fees

2 Nov - 3 Nov

A spacious lobby with a high ceiling, a map mural, seating area, and a fireplace.

A coffee station with two coffee machines and a display of coffee products.

A breakfast bar with a digital menu display, cereal and fruit dispensers, and a yogurt machine.

A hotel room with a bed, a blue sofa, a small table, and a wall-mounted artwork.

10. Holiday Inn Express Hotel and Suites St. Charles by IHG

St. Charles

sharon

Rp2.144.618

Rp2.464.745 total

includes taxes & fees

22 Nov - 23 Nov

A reception desk with a wooden counter, a computer, a telephone, and a small plant. There are three pendant lights above the desk.

A swimming pool with a tiled deck, a sunroof, and a seating area with chairs.

A spacious hotel lobby with a seating area, a kitchen, and a staircase.

A hotel room with a sofa, a red armchair, a desk with a lamp, and framed artwork on the wall.

11. Country Inn & Suites by Radisson, St. Peters, MO

St. Charles

Joseph

Rp1.427.342

Rp1.640.731 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with a bed, a desk with two chairs, a TV, and a mirror.

A modern hotel room with a kitchenette, a sofa, a flat-screen TV, and a bed.

12. Candlewood Suites St Louis St Charles by IHG

St. Charles

Jeffrey

Rp1.781.208

Rp2.047.090 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a reception desk, seating area, and a fireplace.

A hotel room with a large bed, two bedside lamps, a nightstand with a phone and alarm clock, and two framed floral pictures on the wall.

A lobby with a fireplace, several potted plants, a television, and a sofa.

A living room with a beige sofa, a wooden coffee table, a patterned rug, a potted plant, and two framed pictures on the wall.

13. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

St. Charles

ROSE

Rp1.619.100

Rp1.876.973 total

includes taxes & fees

26 Oct - 27 Oct

A reception area with a counter, a clock, a coffee station, and a seating area with chairs and a table.

A person wearing a blue glove cleaning a reflective surface, likely a table or counter.

A motel with a row of rooms, each with a door and windows. There is a parking lot in front of the motel.

A hotel room with a bed, a bedside table, and a window with curtains.

14. Relax Inn Saint Charles

St. Charles

Tim

Rp1.133.496

Rp1.302.621 total

includes taxes & fees

23 Oct - 24 Oct

A spacious lobby with a staircase, a reception desk, and a green wall with white floral patterns.

A Sleep Inn hotel with a prominent tower, multiple entry points, and a well-maintained exterior.

A hotel room with a bed, two bedside tables with lamps, a headboard, a green accent wall, and framed pictures.

A hotel room with a kitchenette, a sofa, a lamp, and a painting on the wall.

15. Sleep Inn Saint Charles North

St. Charles

Christine

Rp1.315.065

Rp1.511.364 total

includes taxes & fees

22 Nov - 23 Nov

A multi-story hotel with a parking lot in front.

A person operating a front-loading washing machine in a laundromat with multiple machines.

A hallway with a reception desk, a no-smoking sign, and a door.

A person in military uniform at a counter with a computer monitor, a card reader, and a coffee machine.

16. WoodSpring Suites St Louis St Charles

St. Charles

Erica

Rp1.529.140

Rp1.757.395 total

includes taxes & fees

25 Oct - 26 Oct

A spacious living room with a large sectional sofa, a coffee table, and a fireplace. There is a television mounted on the wall and a chandelier hanging from the ceiling.

A hotel room with a large bed, bedside tables with lamps, a flat-screen TV, and a large window with curtains.

A spacious lobby with a high ceiling, a seating area with sofas and chairs, a reception desk, and a television screen.

A spacious living room with a modern chandelier, a fireplace, and a large television on the wall.

17. Best Western Plus The Charles Hotel

St. Charles

Tony

Rp1.666.959

Rp1.932.457 total

includes taxes & fees

27 Oct - 28 Oct

A hotel room with a large bed, a desk, and a television.

A gym with exercise equipment, a bench, and a mirrored wall.

A swimming pool with two lanes, a seating area with chairs, and a door leading outside.

A reception area with a wooden reception desk, a digital screen, and framed certificates on the wall.

18. Home2 Suites by Hilton St. Charles St.Louis

St. Charles

Rp2.352.094

Rp2.609.648 total

includes taxes & fees

21 Nov - 22 Nov

A large hotel with a prominent tower and multiple parking areas.

A spacious lobby with a patterned carpet, a reception desk, and a seating area with a sofa and chairs.

A lobby with a large screen displaying "Hollywood Casino" and "Wood Casino" signs, multiple chandeliers, and a polished floor.

A bar area with a long counter, multiple screens, and seating.

19. Hollywood Casino & Hotel St. Louis

Riverport

Nicole

Rp1.698.524

Rp2.259.361 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

20. Wingate by Wyndham St. Louis Airport

St. Ann

Rachal

Rp1.820.790

Rp2.161.968 total

includes taxes & fees

1 Nov - 2 Nov

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Where to stay in St. Charles

Find the best St. Charles areas for the activities you enjoy most.

St. Charles Historic District

A wooden bridge with metal trusses, surrounded by trees.

A historic brick building with arched doorways and a sign that reads "Hot Goods Pen House."

A rustic wooden church with a cross on the roof and a bell.

A red train car with a ladder, set against a sunset sky.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

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Stay near popular St. Charles attractions

A brick-paved street lined with historic buildings and a yellow fire hydrant.

Historic Main Street

9.4/10 (538 reviews)

Missouri's first state capital (1821-1826) features over 100 speciality shops along brick-paved streets. Explore historic buildings with elegant restaurants and boutiques while immersing yourself in 19th-century charm.

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An indoor ice skating rink with a high ceiling and flags.

Family Arena

8.2/10 (179 reviews)

The Family Arena hosts everything from rock concerts to rodeos in its spacious 10,000-seat venue. Arrive early to explore the concessions and merchandise areas before settling in for the main event.

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A classic car with a shiny chrome grille and a golden eagle emblem.

Fast Lane Classic Cars

8.4/10 (62 reviews)

Explore showrooms of meticulously maintained classic cars and hot rods at Fast Lane Classic Cars. Knowledgeable staff share fascinating stories behind each vintage vehicle, delighting car enthusiasts.

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A steel bridge over a calm river with lush greenery and trees in the background.

Katy Trail

9.0/10 (158 reviews)

The Katy Trail spans 240 miles across Missouri on a historic railway corridor, offering river views and charming towns. Cyclists and hikers can explore America's longest rail-trail while sampling local wineries.

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Ameristar Casino St. Charles

8.4/10 (763 reviews)

This expansive casino resort offers vibrant gaming, luxurious accommodation, and diverse dining. Enjoy sophisticated spa services or experience the lively atmosphere at RYSE Nightclub after trying your luck at the tables.

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St Charles Convention Center

8.4/10 (223 reviews)

This premier St. Louis area venue offers versatile spaces for conventions and social gatherings. Its direct connection to Embassy Suites hotel provides exceptional convenience for multi-day event attendees.

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Lindenwood University

8.6/10 (183 reviews)

Founded in 1832, Lindenwood University is the second-oldest higher-education institution west of the Mississippi. Explore its picturesque campus or catch a performance at the J. Scheidegger Centre for the Arts.

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Lewis & Clark Boathouse and Nature Center

8.8/10 (113 reviews)

Step back in time at this museum showcasing full-sized replicas of Lewis and Clark's expedition boats. Explore interactive exhibits and the state's largest indoor mural depicting the historic Missouri River journey.

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Learn more about St. Charles

Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

See all hotels in St. Charles

A bridge over a calm river with a sunset sky.

Top St. Charles Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"They had complementary breakfast and a kick back in the afternoon with two alcoholic drinks for adults. The ambience was really nice. The staff was super sweet. Shout out to the cleaning staff they were amazing with doing their work and also being super friendly in the hallways."

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"Loved the area to the event"

Drury Plaza Hotel St. Louis St. Charles

10/10 Excellent

"The staff was so friendly and helpful- two young women helped us check in and we wanted to make changes- Alyssa and Nina changed our room for us-,we wanted more space because we had our dog with us- they were wonderful- We loved the location too"

Ameristar Casino Resort and Spa

10/10 Excellent

"Room was quite large and very comfortable."

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"The staff were friendly and helpful. It was a wonderful stay a around"

21C Museum Hotel St Louis

10/10 Excellent

"Everything was WONDERFUL"

Comfort Suites St Charles - St Louis

10/10 Excellent

"I truly enjoyed my stay. The staff was excellent. I ran into a problem. They addressed it right away. Everyone was pleasant. I will say again."

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"Exceeded our expectations."

Live by Loews - St.Louis

10/10 Excellent

"Great place to stay."

More cheap stays in St. Charles

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd Maryland Heights MO

Rp1.070.524

Rp1.241.680 total

12 Nov - 13 Nov

includes taxes & fees

4.4/10 (1,003 reviews)

Motel 6 Hazelwood, MO

5781 Campus Ct Hazelwood MO

Rp1.070.344

Rp1.308.198 total

1 Nov - 2 Nov

includes taxes & fees

8.4/10 Very good! (2,265 reviews)

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO

Rp1.283.166

Rp1.475.487 total

29 Oct - 30 Oct

includes taxes & fees

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO

Rp1.332.727

Rp1.558.344 total

15 Nov - 16 Nov

includes taxes & fees

7.8/10 Good! (1,011 reviews)

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

Rp1.619.100

Rp1.922.487 total

26 Oct - 27 Oct

includes taxes & fees

The West End

4215 Lindell Blvd St. Louis MO

Rp1.773.274

Rp2.433.312 total

28 Oct - 29 Oct

includes taxes & fees

Frequently asked questions

Where is the best place for a stay in St. Charles?

Based on our traveller data, Ameristar Casino Resort and Spa is one of the top choices for your stay. This hotel is steps from Ameristar Casino St. Charles, and offers a full-service spa and a casino. Other good choices for your stay include Hampton Inn St. Charles St. Peters and Country Inn & Suites by Radisson, St. Charles Historic District. See all available top hotels, or vacation rentals in St. Charles.

If I need to cancel my hotel reservation in St. Charles, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in St. Charles.

What's the best budget-friendly hotel in St. Charles?

Based on reviews, Home2 Suites by Hilton St. Charles St.Louis is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in St. Charles.

What's the best family accommodation in St. Charles?

Country Inn & Suites by Radisson, St. Charles Historic District is a hotel with an indoor pool and free parking, and it's a top choice on Expedia for families. Other options for your stay with the children include Drury Plaza Hotel St. Louis St. Charles and Comfort Suites St Charles - St Louis. Also, attractions in the area such as St. Louis Zoo and Centene Community Ice Center are fun for children of all ages. Find more child-friendly accommodations in St. Charles.

What is the favourite LGBTQ-friendly hotel in St. Charles?

Embassy Suites by Hilton St. Louis St. Charles is a top LGBTQ-friendly hotel, and features free breakfast and sofa beds. Hampton Inn St. Charles St. Peters and Country Inn & Suites by Radisson, St. Charles Historic District are two other good choices for your stay. See all available hotels listed as LGBTQ-friendly in St. Charles.

What's the best dog-friendly place to stay in St. Charles?

Embassy Suites by Hilton St. Louis St. Charles is a top hotel for people travelling with their pets, and offers a restaurant and sofa beds for its human guests. Other good options for you and your pet include Hampton Inn St. Charles St. Peters and Drury Plaza Hotel St. Louis St. Charles. See more pet-friendly hotel accommodations in St. Charles.

What's the best high-end hotel in St. Charles?

Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Find more luxury hotels in St. Charles.

Where's the best place to stay if you'd like to visit the local casinos in St. Charles?

Ameristar Casino Resort and Spa is a top hotel featuring a casino and a full-service spa. See more casino hotels in St. Charles.

What's the best accommodation for a golf trip to St. Charles?

Hampton Inn St. Charles St. Peters is a top hotel that has an adjacent golf course and features free WiFi. You can tee off at Missouri Bluffs Golf Course during your trip. See more golf hotels in St. Charles.

What are some accommodation options with pools in St. Charles?

Comfort Suites St Charles - St Louis is a top hotel with an indoor pool, free full breakfast and free WiFi. Americas Best Value Inn & Suites St. Louis, St. Charles Inn is one more option that offers an on-site pool. View all hotels with pools in St. Charles.

What is the best spa hotel in St. Charles?

Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino, a 24-hour fitness centre and an outdoor pool. Treat yourself to a facial, body scrub or hydrotherapy at Ara. See all spa hotels in St. Charles.

What is staying in St. Charles like?

Families will find child-friendly activities in St. Charles, and visitors give high marks for the shopping, casinos and top-notch restaurants. This city also attracts tourists with its live music, riverfront and theatres. A top sight in the area is St. Louis Zoo. In St. Charles, there are 178 hotels and other accommodation options to choose from. Find out more about St. Charles.

What are the top places to visit in St. Charles?

Notable for its historic sites, landmarks like Historic Main Street, Lewis & Clark Boathouse and Nature Center and First Missouri State Capitol Historic Site are not to be missed. Natural beauty is on display at Katy Trail, Mississippi River and Missouri River. Additionally, you'll find St. Louis Zoo in the area. Take a look at what more there is to see and do in Expedia's St. Charles guide.

What's the seasonal weather like in St. Charles?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.

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Book Hotels in St. Charles on Expedia.com

Find hotels in St. Charles, MO from Rp1.241.680

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in St. Charles

Check prices for these dates

Filter by

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Guest rating

Our top choices for St. Charles hotels

1. Country Inn & Suites by Radisson, St. Charles Historic District

2. Ameristar Casino Resort and Spa

3. Embassy Suites by Hilton St. Louis St. Charles

4. Drury Plaza Hotel St. Louis St. Charles

5. Hampton Inn & Suites St. Charles Old Town Area

6. Comfort Suites St Charles - St Louis

7. Hampton Inn St. Charles St. Peters

8. Tru by Hilton St. Charles St. Louis, MO

9. Super 8 by Wyndham St Charles

10. Holiday Inn Express Hotel and Suites St. Charles by IHG

11. Country Inn & Suites by Radisson, St. Peters, MO

12. Candlewood Suites St Louis St Charles by IHG

13. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

14. Relax Inn Saint Charles

15. Sleep Inn Saint Charles North

16. WoodSpring Suites St Louis St Charles

17. Best Western Plus The Charles Hotel

18. Home2 Suites by Hilton St. Charles St.Louis

19. Hollywood Casino & Hotel St. Louis

20. Wingate by Wyndham St. Louis Airport

Where to stay in St. Charles

St. Charles Historic District

Stay near popular St. Charles attractions

Historic Main Street

Family Arena

Fast Lane Classic Cars

Katy Trail

Ameristar Casino St. Charles

St Charles Convention Center

Lindenwood University

Lewis & Clark Boathouse and Nature Center

Learn more about St. Charles

Top St. Charles Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Pear Tree Inn St. Louis Near Union Station

Drury Plaza Hotel St. Louis St. Charles

Ameristar Casino Resort and Spa

Drury Plaza Hotel St. Louis Union Station

21C Museum Hotel St Louis

Comfort Suites St Charles - St Louis

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Live by Loews - St.Louis

More cheap stays in St. Charles

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Motel 6 Hazelwood, MO

Best Western St. Louis Inn

Tru By Hilton St. Louis Downtown

Pear Tree Inn St. Louis Airport

The West End

Frequently asked questions

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