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Our top choices for St. Charles luxury hotels

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very good, (1003)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is Rp2.835.800
Rp3.592.404 total
includes taxes & fees
29 Dec - 30 Dec
Ameristar Casino Resort and Spa

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1451)
"Awesome place to stay!!"
United States
Kaitlyn
The price is Rp1.657.192
Rp2.172.480 total
includes taxes & fees
1 Jan - 2 Jan 2026
River City Casino & Hotel

The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
8.8 out of 10, Excellent, (134)
"Great place for a weekend getaway! The Inn was clean, staff is extremely helpful. The Inn is within walking distance with unique shops, restaurants, anything you needed."
United States
Angelia
The price is Rp2.260.035
Rp2.573.092 total
includes taxes & fees
20 Jan - 21 Jan 2026
The Inn at Elijah McLeans

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1171)
"Staff was helpful at suggesting places to eat and shop"
United States
Ann Marie
The price is Rp1.626.205
Rp1.934.028 total
includes taxes & fees
25 Jan - 26 Jan 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (681)
"The gym was amazing! "
United States
Hannah
The price is Rp1.995.527
Rp2.349.494 total
includes taxes & fees
28 Dec - 29 Dec
Le Méridien St. Louis Clayton

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1912)
"The staff was very friendly and courteous. The hotel itself is quirky and fun"
United States
Deborah
The price is Rp1.885.998
Rp2.242.999 total
includes taxes & fees
28 Dec - 29 Dec
Moonrise Hotel

White House at Grand Central

White House at Grand Central
4.0 star property
Grand Center
8.6 out of 10, Excellent, (124)
"Very clean and very friendly people "
United States
Mary
The price is Rp1.090.060
Rp2.352.968 total
includes taxes & fees
6 Jan - 7 Jan 2026
White House at Grand Central

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (4024)
"Everything was great!"
United States
Kathryn
The price is Rp1.657.359
Rp1.954.507 total
includes taxes & fees
30 Dec - 31 Dec
Hyatt Regency St. Louis at The Arch

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1064)
"I loved the service, room cleanliness, club lounge offered a nice variety of food and treats. The property is noticeably old but well maintained. "
United States
Ingrid I
The price is Rp2.042.402
Rp2.389.366 total
includes taxes & fees
17 Jan - 18 Jan 2026
Renaissance St. Louis Airport Hotel

DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
4.0 star property
Chesterfield
8.6 out of 10, Excellent, (1001)
"Great hotel!"
United States
John
The price is Rp2.048.348
Rp2.375.838 total
includes taxes & fees
16 Jan - 17 Jan 2026
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Charles Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, First Missouri State Capitol Historic Site and Katy Trail. If you have a little extra time during your trip, you might want to make a stop at Lewis & Clark Boathouse and Nature Center and St Charles Convention Center.