A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

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Check availability on St. Charles Spa Hotels

Tonight
23 Sept - 24 Sept
Tomorrow
24 Sept - 25 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for St. Charles hotels with a spa

A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A bakery display case with various pastries and cakes.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
Rp2.669.187
Rp3.416.086 total
includes taxes & fees
12 Oct - 13 Oct
Ameristar Casino Resort and Spa
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A well-lit lobby with a chandelier, seating area, and decorative plants.
A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.

2. Truitt Hotel

Truitt Hotel
Lafayette Square
Rp3.004.512
Rp3.647.263 total
includes taxes & fees
27 Sept - 28 Sept
Truitt Hotel
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A modern bathroom with a bathtub, a vanity with a mirror, and a shower area.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."

3. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
Rp2.563.722
Rp3.086.969 total
includes taxes & fees
18 Oct - 19 Oct
21C Museum Hotel St Louis
A couple relaxing by a window overlooking a bridge and water.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A modern hotel lobby with a glass facade, seating area, and a staircase.

4. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
Rp6.692.625
Rp7.825.553 total
includes taxes & fees
5 Oct - 6 Oct
Four Seasons Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
A couple standing on a balcony with a cityscape view.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.

5. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
Rp11.070.196
Rp12.923.157 total
includes taxes & fees
18 Oct - 19 Oct
The Ritz-Carlton, St. Louis
View all properties

Choose what matters most at spa hotels in St. Charles

Pool
Hot tub
Breakfast included
4 stars
5 stars

Top St. Charles Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Na"
Rachel 2-night trip
Posted less than an hour ago
Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

10/10 Excellent
"Room was clean and the amenities are great. Many options for food and drinks in the building and near by. Next door from the Gateway Arch. Great view."
Carlos 4-night trip
Posted less than an hour ago
Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Stayed here for the Lionel Richie concert at the Muny. Perfect."
Terry 1-night trip
Posted 3 hours ago
Drury Plaza Hotel St. Louis Union Station
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent
"Friendly staff, clean room, walking distance to shops and restaurants."
Laurene 1-night trip
Posted 4 hours ago
Country Inn & Suites by Radisson, St. Charles Historic District
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

8/10 Good
"Staff is always so friendly at this hotel"
Kim 2-night trip
Posted 5 hours ago
Drury Plaza Hotel St. Louis St. Charles
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

8/10 Good
"Good"
Sudhakar 1-night trip
Posted 15 hours ago
Pear Tree Inn St. Louis Near Union Station
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Great, friendly staff. The rooms are clean and it is easy to park."
Maryanne 1-night trip
Posted 22 hours ago
Ameristar Casino Resort and Spa
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

10/10 Excellent
"Very friendly staff"
Anthony 1-night trip
Posted 1 day ago
Embassy Suites by Hilton St. Louis St. Charles

Frequently asked questions

Looking for a spa hotel in St. Charles?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers highly recommend the restaurants in St. Charles. Enjoy the historical sites and riverfront during your holiday. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in St. Charles?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino, a 24-hour fitness centre and an outdoor pool. Treat yourself to a facial, body scrub or hydrotherapy at Ara.
How many spa hotels will I find in St. Charles?
Among Expedia's 180 accommodation options in St. Charles, there is 1 spa hotel.
What's there to see and do in St. Charles?
Experience all that St. Charles has to offer when you visit Historic Main Street, Katy Trail and Lewis & Clark Boathouse and Nature Center. If you have some spare time during your trip, you might want to check out St Charles Convention Center and Ameristar Casino St. Charles.
What is a St. Charles spa hotel?
Spa hotels in St. Charles provide lodging and have a full on-site spa which offers services such as couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.

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