Search Hotels in Zona Ospedaliera, Naples

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22 Dec - 23 Dec
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23 Dec - 24 Dec
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26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for Zona Ospedaliera hotels

Reception
HOTEL FEDERICO II

HOTEL FEDERICO II

HOTEL FEDERICO II
3.0 star property
Zona Ospedaliera
7.4 out of 10, Good, (156)
"The place is quite with friendly staff"
Canada
lina
HOTEL FEDERICO II
Deluxe Double or Twin Room, Balcony (#1) | Minibar, desk, blackout curtains, soundproofing
F Rooms

F Rooms

F Rooms
Zona Ospedaliera
7.8 out of 10, Good, (8)
"Nobody to open the door."
Canada
Mihai
The price is Rp1.408.612
Rp1.725.995 total
includes taxes & fees
5 Jan - 6 Jan 2026
F Rooms
Seasonal outdoor pool
Hotel Mega Mare

Hotel Mega Mare

Hotel Mega Mare
3.0 star property
29.1 km from Zona Ospedaliera
8.4 out of 10, Very good, (729)
"Breath taking view."
United States
Edlouie
The price is Rp1.107.276
Rp1.218.004 total
includes taxes & fees
24 Dec - 25 Dec
Hotel Mega Mare
Couples treatment room(s), sauna, hot tub, steam room
La Medusa Dimora di Charme

La Medusa Dimora di Charme

La Medusa Dimora di Charme
4.0 star property
30.6 km from Zona Ospedaliera
9.6 out of 10, Exceptional, (578)
"The property was beautiful. Wonderful lobby and excellent room. Wonderful views of Vesuvius. The grounds have numerous orange trees and we got fresh squeezed orange juice for breakfast. We did not utilize the pool or spa and spent our days seeing the ruins of Herculaneum, Oplontis, Villa San Marco, and Villa San Ariana. Wee hadd seen Pompeii before. We also travelled to Naples and saw the docks, saw the Duomo, and saw the amazing MANN (MUSEO ARCHEALOGICA NATIONALE NAPLES`0."
United States
Charles
The price is Rp3.756.306
Rp4.210.391 total
includes taxes & fees
28 Dec - 29 Dec
La Medusa Dimora di Charme
Front of property – evening/night
Hotel Plana

Hotel Plana

Hotel Plana
4.0 star property
23.6 km from Zona Ospedaliera
9.0 out of 10, Wonderful, (221)
"Very good stay, clean and comfortable, with very good breakfast but needs a pool."
United States
Joshua
Hotel Plana
Family Room | Down duvets, memory-foam beds, minibar, in-room safe
Boutique Hotel Metro 900

Boutique Hotel Metro 900

Boutique Hotel Metro 900
4.0 star property
Mergellina, 4.3 km from Zona Ospedaliera
8.8 out of 10, Excellent, (162)
"This hotel was terrific. Room was lovely, location is right next to the train station, but extremely quiet. Definitely a find."
United States
kathleen
Boutique Hotel Metro 900
Private beach nearby, free beach cabanas, beach shuttle, sun-loungers
Hotel Mary

Hotel Mary

Hotel Mary
4.0 star property
29.3 km from Zona Ospedaliera
9.2 out of 10, Wonderful, (865)
"Very nice hotel with a nice view across the gulf of Neapel."
Germany
Ingo
Hotel Mary
Exterior
Holiday Inn Naples by IHG

Holiday Inn Naples by IHG

Holiday Inn Naples by IHG
4.0 star property
6.2 km from Zona Ospedaliera
8.2 out of 10, Very good, (1002)
"Room was spotless and stocked with everything you need. Staff was welcoming and quick to respond to any needs. Very quiet and great location for quick run to the airport."
United States
Layna
The price is Rp1.123.323
Rp1.647.540 total
includes taxes & fees
9 Jan - 10 Jan 2026
Holiday Inn Naples by IHG
Exterior
Hotel Tiempo

Hotel Tiempo

Hotel Tiempo
3.0 star property
6.7 km from Zona Ospedaliera
8.2 out of 10, Very good, (790)
"Convenient location close to the terminal. Awesome breakfast bar, great coffee, super clean rooms! "
United States
Marlin
The price is Rp1.200.352
Rp1.496.909 total
includes taxes & fees
23 Dec - 24 Dec
Hotel Tiempo
Reception
Villa Elisio Hotel & Spa

Villa Elisio Hotel & Spa

Villa Elisio Hotel & Spa
Rione Sanità, 3.2 km from Zona Ospedaliera
8.4 out of 10, Very good, (185)
"Hotel was very clean, very helpful staff and a great breakfast"
United Kingdom
Manoranjan
Villa Elisio Hotel & Spa
Terrace/patio
Gold Tower Lifestyle Hotel

Gold Tower Lifestyle Hotel

Gold Tower Lifestyle Hotel
4.0 star property
7 km from Zona Ospedaliera
9.2 out of 10, Wonderful, (553)
"This hotel was amazing, the view was breathtaking, although the weather wasn't too good with light showers, my family and I enjoyed our stay. "
United States
Aurore Murielle
The price is Rp1.668.937
Rp2.051.580 total
includes taxes & fees
23 Dec - 24 Dec
Gold Tower Lifestyle Hotel
Terrace/patio
CX Naples Centrale

CX Naples Centrale

CX Naples Centrale
Naples City Centre, 5.6 km from Zona Ospedaliera
9.6 out of 10, Exceptional, (17)
"Great place for a family with children "
United States
Jared
The price is Rp1.321.322
Rp1.629.976 total
includes taxes & fees
6 Jan - 7 Jan 2026
CX Naples Centrale
Seasonal outdoor pool, open 9:00 AM to 7:00 PM, pool umbrellas
Towers Hotel Stabiae Sorrento Coast

Towers Hotel Stabiae Sorrento Coast

Towers Hotel Stabiae Sorrento Coast
4.0 star property
28.4 km from Zona Ospedaliera
8.6 out of 10, Excellent, (593)
"This hotel is beautiful and has amazing views and amenities, however, you will need a taxi or a car to get around as it’s very secluded from everything. "
United States
Geraldine
The price is Rp1.360.904
Rp1.575.449 total
includes taxes & fees
11 Jan - 12 Jan 2026
Towers Hotel Stabiae Sorrento Coast
Superior Double Room | Minibar, in-room safe, desk, blackout curtains
Hotel Royal Caserta

Hotel Royal Caserta

Hotel Royal Caserta
4.0 star property
24.3 km from Zona Ospedaliera
8.8 out of 10, Excellent, (824)
"Comfortable stay, good breakfast selection and right next to the train station & Reggia Caserta!"
Australia
Nathan
The price is Rp1.947.985
Rp2.221.238 total
includes taxes & fees
23 Dec - 24 Dec
Hotel Royal Caserta
Italian cuisine
Hotel dei Cavalieri Caserta

Hotel dei Cavalieri Caserta

Hotel dei Cavalieri Caserta
4.0 star property
25 km from Zona Ospedaliera
9.0 out of 10, Wonderful, (540)
"Great location"
United States
Andréa
The price is Rp1.989.887
Rp2.267.330 total
includes taxes & fees
26 Dec - 27 Dec
Hotel dei Cavalieri Caserta
Bar (on property)
Buono Hotel

Buono Hotel

Buono Hotel
3.0 star property
Poggioreale, 6.2 km from Zona Ospedaliera
8.0 out of 10, Very good, (347)
"staff was very friendly."
United States
Jose
The price is Rp891.526
Rp1.157.200 total
includes taxes & fees
24 Dec - 25 Dec
Buono Hotel
Exclusive Suite | Private spa tub
Hotel & Resort Tre Fontane Luxury

Hotel & Resort Tre Fontane Luxury

Hotel & Resort Tre Fontane Luxury
10.9 km from Zona Ospedaliera
9.2 out of 10, Wonderful, (384)
"A great hotel with excellent food and great staff. Being near Christmas was ideal to just walk to the Christmas fair"
United Kingdom
Patricia
The price is Rp1.797.317
Rp1.977.049 total
includes taxes & fees
28 Dec - 29 Dec
Hotel & Resort Tre Fontane Luxury
Front of property
Royal Continental Hotel Naples

Royal Continental Hotel Naples

Royal Continental Hotel Naples
4.0 star property
San Ferdinando, 5.3 km from Zona Ospedaliera
8.6 out of 10, Excellent, (1372)
"great location very friendly staff very clean Fantastic Breakfast"
United States
gennaro
The price is Rp2.638.918
Rp3.118.559 total
includes taxes & fees
6 Jan - 7 Jan 2026
Royal Continental Hotel Naples
Exterior
The Five Rooms Napoli

The Five Rooms Napoli

The Five Rooms Napoli
Naples City Centre, 5.1 km from Zona Ospedaliera
9.6 out of 10, Exceptional, (557)
"Staff was courteous and very helpful with local knowledge, room was "
Canada
Desiree Barbara Nicole
The price is Rp1.845.460
Rp2.206.528 total
includes taxes & fees
27 Dec - 28 Dec
The Five Rooms Napoli
Deluxe Studio Suite | Minibar, in-room safe, desk, soundproofing
Partenope Relais

Partenope Relais

Partenope Relais
4.0 star property
San Ferdinando, 5 km from Zona Ospedaliera
8.2 out of 10, Very good, (403)
"Stunning view and comfort."
United States
greg
The price is Rp2.581.504
Rp3.055.403 total
includes taxes & fees
8 Jan - 9 Jan 2026
Partenope Relais
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Zona Ospedaliera

Find the best Zona Ospedaliera areas for the activities you enjoy most. Learn more about Zona Ospedaliera
Learn more about Zona Ospedaliera
San Lorenzo Maggiore showing a city and a house

Naples City Centre

Known for its abundant dining options and interesting museums, there's plenty to explore in Naples City Centre. Top attractions like Port of Naples and Mercato di Porta Nolana are major draws, and you can catch the metro at Garibaldi Tram Stop or EAV - Capolinea Porta Nolana Tram Stop to see more of the city.

Historical Center

Port of Naples and Via Toledo are top sights in Historical Center, and you should be sure to explore the popular shops. Hop aboard the metro at Toledo Station or Municipio Station to see more sights in the area.

Chiaia

Mingle with the locals in the historic park, explore the little aquarium or gaze out to sea from this stylish part of the Italian city of “Napoli.”

Pendino

If you're spending time in Pendino, check out sights like Corso Umberto I or Calata di Massa Port and hop on the metro to see more of the city at Duomo Station or Via Marina - Duomo Tram Stop.

San Lorenzo Maggiore featuring interior views

Decumani

While you're in Decumani, take in top sights like Via San Gregorio Armeno and jump on the metro at Dante Station to see more of the city.

Top Zona Ospedaliera Hotel Reviews

Hotel Antiche Mura

Hotel Antiche Mura

10/10 Excellent
"Wonderful experience "
samuel 1-night trip
Posted 9 days ago
Hotel Antiche Mura

Frequently asked questions

What's it like in Zona Ospedaliera?
Zona Ospedaliera is a neighbourhood that travellers like for its restaurants.
Where is the best place to stay in Zona Ospedaliera?
Based on Expedia customer reviews, HOTEL FEDERICO II is the highest ranked property in Zona Ospedaliera. This hotel offers a restaurant and free parking.
How many hotels should I expect to find in the Zona Ospedaliera area?
Book one of Expedia's 6 hotels and other accommodation options in Zona Ospedaliera and start exploring everything Naples has to offer.
If I need to cancel my hotel reservation in Zona Ospedaliera, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals in Zona Ospedaliera.
What is there to do around this Naples neighbourhood?
Teatro Il Primo, Parco Urbano dei Camaldoli and Sacra Ruota degli Esposti are just a few of the places to visit in and around Zona Ospedaliera. While you're out sightseeing, Basilica SS Annunziata and Il Carosello dei Piccoli are a couple of additional sights to visit in Naples.
How can I get around Zona Ospedaliera and the greater Naples area?
Ready to get out and explore the city? Policlinico Station is the closest metro station.