The Best Hotels Closest to 21c Museum Hotel in Louisville - 2026 Updated Prices

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Our top choices for 21c Museum Hotel hotels

A wooden staircase with a balustrade leading to a landing.

A bedroom with a bed, a dresser, a television, and a desk with a lamp.

A two-story brick building with a white porch and a sign reading "Hotel".

A brick building with a covered porch, columns, and potted plants.

1. Market Street Inn

2.1 km from 21c Museum Hotel

Anissa

Rp2.959.302

Rp3.343.901 total

includes taxes & fees

24 Aug - 25 Aug

An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

A bar with shelves of liquor bottles and a bartender preparing drinks.

An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.

A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

2. Hotel Distil, Autograph Collection

Downtown Louisville, 0.8 km from 21c Museum Hotel

Jasmine

Rp3.595.117

Rp4.230.014 total

includes taxes & fees

6 Sept - 7 Sept

A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

A room with a red velvet sofa, a blue armchair, and a small round table with books.

A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.

A living room with a sofa, a fireplace, a staircase, and a chandelier.

3. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from 21c Museum Hotel

Casey

Rp2.479.751

Rp2.878.371 total

includes taxes & fees

24 Aug - 25 Aug

A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.

A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.

A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.

4. Stellar Suites

East Market District, 2.2 km from 21c Museum Hotel

Brad

Rp1.785.605

Rp2.999.558 total

includes taxes & fees

23 Aug - 24 Aug

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.

A spacious lobby with a large seating area, a chandelier, and a patterned rug.

A spacious hotel lobby with a central seating area, stone accent walls, and a chandelier.

5. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.1 km from 21c Museum Hotel

Jon

Rp2.033.403

Rp2.392.502 total

includes taxes & fees

6 Sept - 7 Sept

A grand lobby with ornate columns, plush seating, and a chandelier.

A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.

A grand lobby with ornate ceiling, large windows, and classic furniture.

A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

6. The Brown Hotel

Downtown Louisville, 1.2 km from 21c Museum Hotel

Anthony

Rp2.363.255

Rp2.780.607 total

includes taxes & fees

24 Aug - 25 Aug

An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

A modern restaurant with high tables and booths, wooden ceiling panels, and framed pictures on the walls.

A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.

A modern hotel lobby with a reception desk, seating area, and a large abstract ceiling artwork.

7. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2 km from 21c Museum Hotel

Jennifer

Rp2.095.684

Rp2.465.782 total

includes taxes & fees

24 Aug - 25 Aug

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

A modern restaurant interior with a staircase, round tables, and a brick wall.

A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".

8. The Grady

Downtown Louisville, 0.1 km from 21c Museum Hotel

Conswaila

Rp2.889.188

Rp3.399.590 total

includes taxes & fees

30 Aug - 31 Aug

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

A modern interior with a fireplace, bookshelves, and seating areas.

A lobby with a marble floor, a reception desk, and a large chandelier.

A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

9. Omni Louisville Hotel

Downtown Louisville, 0.8 km from 21c Museum Hotel

Jon-Michael

Rp2.840.128

Rp3.341.695 total

includes taxes & fees

23 Aug - 24 Aug

A classical gold statue in front of a multi-story building with large windows and a brick facade.

A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.

A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

10. 21c Museum Hotel Louisville

Downtown Louisville, < 0.1 km from 21c Museum Hotel

Craig

Rp3.176.892

Rp3.826.824 total

includes taxes & fees

22 Aug - 23 Aug

An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.

A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from 21c Museum Hotel

Jeffery

Rp2.896.119

Rp3.407.574 total

includes taxes & fees

30 Aug - 31 Aug

An outdoor seating area with wicker furniture and a fire pit.

An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.

A modern hotel lobby with a large central table, multiple seating areas, and large windows offering city views.

A modern lounge area with seating, tables, and a view of the city through large windows.

12. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from 21c Museum Hotel

Tina

Rp1.730.480

Rp2.036.082 total

includes taxes & fees

6 Sept - 7 Sept

An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

A modern coffee shop interior with a central island, wooden counter, and large windows.

A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.

A modern bar area with sofas, tables, and a bar stocked with bottles.

13. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.9 km from 21c Museum Hotel

Angela

Rp1.900.278

Rp2.235.867 total

includes taxes & fees

6 Sept - 7 Sept

A modern bar area with a circular bar, multiple seating options, and a large screen.

A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.

A modern interior with a central wooden table, refrigerated beverage dispensers, and shelves stocked with snacks and condiments.

14. Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from 21c Museum Hotel

Riley

Rp1.841.088

Rp2.166.223 total

includes taxes & fees

13 Sept - 14 Sept

A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

A modern living room with a sofa, ottomans, a coffee table, and a rug.

A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.

A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

15. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from 21c Museum Hotel

Zacarias

Rp1.703.808

Rp2.004.702 total

includes taxes & fees

6 Sept - 7 Sept

A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

A modern interior with a central seating area, a television screen, and a wooden partition with various items displayed.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.

16. AC Hotel Louisville Downtown

East Market District, 2 km from 21c Museum Hotel

David

Rp2.158.778

Rp2.540.018 total

includes taxes & fees

28 Aug - 29 Aug

A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.

A yellow coffee shop counter with a menu board above, displaying various coffee and food items.

A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

A brightly lit grocery store with yellow shelving and a central checkout counter.

17. Hotel Genevieve part of JdV by Hyatt

East Market District, 2 km from 21c Museum Hotel

Christina

Rp2.395.980

Rp2.819.109 total

includes taxes & fees

30 Aug - 31 Aug

A covered patio with a stone wall, a glass table, and a bench.

A grand room with a fireplace, a staircase, and a chandelier.

A garden pathway with a lantern, potted plants, and a white fence.

18. Central Park Bed & Breakfast

Old Louisville, 2.9 km from 21c Museum Hotel

Angie

Rp2.332.797

Rp2.707.635 total

includes taxes & fees

31 Aug - 1 Sept

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.

A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

19. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from 21c Museum Hotel

Dina

Rp2.550.951

Rp3.001.448 total

includes taxes & fees

2 Sept - 3 Sept

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.

A hotel dining area with long tables, booths, and a bar.

A modern hotel room with a living area, a dining area, and a bedroom.

20. Embassy Suites Louisville Downtown

Downtown Louisville, 0.8 km from 21c Museum Hotel

Spencer

Rp2.305.897

Rp2.713.119 total

includes taxes & fees

5 Sept - 6 Sept

View all properties

Compare popular hotels close to 21c Museum Hotel

Property	Property class	Guest rating
Market Street Inn	9.8 Exceptional 124 reviews	View
Hotel Distil, Autograph Collection	9.6 Exceptional 493 reviews	View
DuPont Mansion Bed & Breakfast	9.6 Exceptional 145 reviews	View
Stellar Suites	9.6 Exceptional 146 reviews	View
Homewood Suites by Hilton Louisville Downtown, KY	9.4 Exceptional 1,014 reviews	View

Top 21c Museum Hotel Hotel Reviews

Towneplace Suites By Marriott Louisville Downtown

10/10 Excellent

"Very clean"

Embassy Suites Louisville Downtown

10/10 Excellent

"An amazing hotel for the price! Will return!"

21c Museum Hotel Louisville

10/10 Excellent

"It’s beautiful and unique; also well situated…."

Hyatt Regency Louisville

10/10 Excellent

"Amazing rooms, comfortable King beds, loved the views from my room, and the replenishment daily of coffee and water. Hotel gym had a great selection of weights, weightlifting, machines, and cardio equipment. I also love that the Starbucks was connected directly to the hotel. We did eat breakfast at the restaurant once, it was just OK. It wasn’t great for the price. Otherwise, the hotel itself was gorgeous and the rooms were quiet."

Omni Louisville Hotel

10/10 Excellent

"Such a excellent service,staff was so helpful!"

The Grady

10/10 Excellent

"We had a wonderful stay and look forward to visiting again."

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent

"Very clean and very convenient location with great views! Staff was very nice."

Homewood Suites by Hilton Louisville Downtown, KY

10/10 Excellent

"This was my favorite hotel I’ve stayed in. The staff were amazing, the pool was nice, the lobby was beautiful, and our room was spacious and clean. The day we were there, they served afternoon snacks and drinks (only on Wednesdays), which was a great touch. I would 100% stay here again!"

Aloft by Marriott Louisville Downtown

8/10 Good

"This hotel is very nice and right in the middle of things. They have a restaurant and bar, but sadly didn't use it for breakfast. The room is nice and modern with a comfortable bed. I would return."

Other attractions near 21c Museum Hotel

A historic building with ornate architecture, including columns and decorative moldings.

Louisville Science Center

7.8/10 (6 reviews)

Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.

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Kentucky Center for the Performing Arts

8.8/10 (49 reviews)

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.

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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)

One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

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A wall of wooden baseball bats organized by size and weight.

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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Golden Statue of David

Find out about the history of Louisville when you spend time at Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your trip to Louisville. Stroll along the area's riverfront or experience its great live music.

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Evan Williams Bourbon Experience

8.6/10 (20 reviews)

You can take time to visit Evan Williams Bourbon Experience during your travels to Louisville. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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SAR Genealogical Research Library: NSSAR Library

You can spend time exploring the galleries in SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

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Frequently asked questions

What's the area like around 21c Museum Hotel?

21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near 21c Museum Hotel?

Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Omni Louisville Hotel and Holiday Inn Express & Suites Louisville Downtown by IHG.

How many hotels are there near 21c Museum Hotel?

Expedia has 292 hotels and other accommodation options within a mile from 21c Museum Hotel.

If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?

Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.

What can I see and do near 21c Museum Hotel?

You might want to spend some time browsing the exhibits at Muhammad Ali Center, Louisville Slugger Museum or Frazier International History Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can watch performances at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall if you're interested in local theatre.

Search Hotels Near 21c Museum Hotel, Louisville

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Our top choices for 21c Museum Hotel hotels

1. Market Street Inn

2. Hotel Distil, Autograph Collection

3. DuPont Mansion Bed & Breakfast

4. Stellar Suites

5. Homewood Suites by Hilton Louisville Downtown, KY

6. The Brown Hotel

7. Tempo By Hilton Louisville Downtown Nulu

8. The Grady

9. Omni Louisville Hotel

10. 21c Museum Hotel Louisville

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

12. Towneplace Suites By Marriott Louisville Downtown

13. Aloft by Marriott Louisville Downtown

14. Cambria Hotel Louisville Downtown-Whiskey Row

15. Moxy Louisville Downtown

16. AC Hotel Louisville Downtown

17. Hotel Genevieve part of JdV by Hyatt

18. Central Park Bed & Breakfast

19. Galt House Hotel Trademark Collection by Wyndham

20. Embassy Suites Louisville Downtown

Compare popular hotels close to 21c Museum Hotel

Top 21c Museum Hotel Hotel Reviews

Towneplace Suites By Marriott Louisville Downtown

Embassy Suites Louisville Downtown

21c Museum Hotel Louisville

Hyatt Regency Louisville

Omni Louisville Hotel

The Grady

Galt House Hotel Trademark Collection by Wyndham

Homewood Suites by Hilton Louisville Downtown, KY

Aloft by Marriott Louisville Downtown

Other attractions near 21c Museum Hotel

Louisville Science Center

Kentucky Center for the Performing Arts

Muhammad Ali Center

Louisville Slugger Museum

Golden Statue of David

Kentucky Museum of Art and Craft

Evan Williams Bourbon Experience

SAR Genealogical Research Library: NSSAR Library

Frequently asked questions