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14 Nov - 15 Nov
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15 Nov - 16 Nov
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Our top choices for Kentucky Science Center hotels

An outdoor patio area with round tables and chairs, surrounded by potted plants and a brick chimney.

1. Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Kentucky Science Center
9.8 out of 10, Exceptional, (127 reviews)
"Such a lovely stay at the Market Street Inn. A very charming, comfortable and feels like home kind of place. Carol and Steve are just the kindest owners. They were responsive and accommodating and always available if needed. We also loved meeting Lisa, who made breakfast each morning and took care of any housekeeping needs. We felt like we were treated as family and not just guests. The area and location is perfect, SUCH a cute little town. Plenty of restaurants, shops and entertainment within...
United States
Ryan
The price is Rp4.025.893
Rp4.549.315 total
includes taxes & fees
15 Nov - 16 Nov
Market Street Inn
A restaurant with a high ceiling, exposed brick walls, hanging plants, and a variety of seating arrangements.

2. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Kentucky Science Center
9.6 out of 10, Exceptional, (520 reviews)
"Excellent location and room!"
United States
Athina
The price is Rp3.668.873
Rp4.316.796 total
includes taxes & fees
28 Nov - 29 Nov
Hotel Distil, Autograph Collection
A grand lobby with ornate columns, plush seating, and a chandelier.

3. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Kentucky Science Center
9.4 out of 10, Exceptional, (1,483 reviews)
"Beautiful hotel!"
United States
Brianne
The price is Rp1.940.305
Rp2.282.963 total
includes taxes & fees
22 Nov - 23 Nov
The Brown Hotel
An outdoor patio area with seating, a fire pit, and a pergola with string lights.

4. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Kentucky Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"Nice hotel"
United States
Jeanette
The price is Rp2.075.120
Rp2.441.587 total
includes taxes & fees
24 Nov - 25 Nov
Homewood Suites by Hilton Louisville Downtown, KY
A modern interior with leather sofas, a bookshelf, and a decorative wall with 'The Grady' sign.

5. The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Kentucky Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"Our stay at The Grady was exceptional and we will definitely be back to stay again soon!!"
United States
Greg
The price is Rp2.699.815
Rp3.176.603 total
includes taxes & fees
23 Nov - 24 Nov
The Grady
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

6. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Kentucky Science Center
9.4 out of 10, Exceptional, (1,160 reviews)
"Great stay!"
United States
Addison
The price is Rp1.851.186
Rp2.178.105 total
includes taxes & fees
26 Nov - 27 Nov
Tempo By Hilton Louisville Downtown Nulu
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

7. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
4.0 star property
Old Louisville, 2.8 km from Kentucky Science Center
9.6 out of 10, Exceptional, (152 reviews)
"Great staff, clean rooms, amazing historic vibe, and yummy breakfast!"
United States
Chris
The price is Rp3.316.405
Rp3.849.295 total
includes taxes & fees
15 Nov - 16 Nov
DuPont Mansion Bed & Breakfast
A modern building with a sign for "Stellar Suites."

8. Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Kentucky Science Center
9.4 out of 10, Exceptional, (158 reviews)
"Location was great near meant restaurants and nightspots"
United States
Kevin
The price is Rp1.984.439
Rp3.254.265 total
includes taxes & fees
19 Nov - 20 Nov
Stellar Suites
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

9. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Kentucky Science Center
9.4 out of 10, Exceptional, (2,243 reviews)
"Very very nice property clean well taken care of and great staff would stay again"
United States
James
The price is Rp3.237.027
Rp3.808.695 total
includes taxes & fees
13 Dec - 14 Dec
Omni Louisville Hotel
A steam fountain in a brick alleyway.

10. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Kentucky Science Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is Rp2.769.861
Rp3.350.050 total
includes taxes & fees
6 Dec - 7 Dec
21c Museum Hotel Louisville
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from Kentucky Science Center
9.4 out of 10, Exceptional, (179 reviews)
"Very good breakfast in hotel lobby restaurant. Extremely nice servers. Reasonably priced."
United States
Paul
The price is Rp2.672.277
Rp3.144.202 total
includes taxes & fees
30 Nov - 1 Dec
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A horse statue with a plaque in a modern interior space with a dining area and large windows.

12. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Kentucky Science Center
9.2 out of 10, Wonderful, (1,018 reviews)
"Location was perfect and staff was very friendly."
United States
Sarah
The price is Rp1.733.211
Rp2.039.296 total
includes taxes & fees
13 Dec - 14 Dec
Cambria Hotel Louisville Downtown-Whiskey Row
A covered patio with a stone wall, a glass table, and a bench.

13. Central Park Bed & Breakfast

Central Park Bed & Breakfast
3.5 star property
Old Louisville, 3 km from Kentucky Science Center
9.4 out of 10, Exceptional, (102 reviews)
"Amazing stay and hospitality. Will stay again"
United States
Stephen
The price is Rp3.109.039
Rp3.608.793 total
includes taxes & fees
16 Nov - 17 Nov
Central Park Bed & Breakfast
A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

14. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Kentucky Science Center
9.2 out of 10, Wonderful, (865 reviews)
"Amazing staff and location!!"
United States
Priscilla
The price is Rp2.020.866
Rp2.377.752 total
includes taxes & fees
14 Dec - 15 Dec
Moxy Louisville Downtown
A bar with multiple shelves of liquor bottles and glasses.

15. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from Kentucky Science Center
9.2 out of 10, Wonderful, (1,005 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is Rp2.226.958
Rp2.620.239 total
includes taxes & fees
25 Nov - 26 Nov
Aloft by Marriott Louisville Downtown
A bar area with a neon sign, red seating, and a bar counter.

16. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Kentucky Science Center
9.2 out of 10, Wonderful, (1,085 reviews)
"Gorgeous, clean room. Great onsite coffee shop and restaurant."
United States
Brittney
The price is Rp2.605.279
Rp3.065.370 total
includes taxes & fees
19 Nov - 20 Nov
Hotel Genevieve part of JdV by Hyatt
A brick building with outdoor seating and a fire pit.

17. TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North
3.0 star property
2.2 km from Kentucky Science Center
9.2 out of 10, Wonderful, (748 reviews)
"Room was clean, breakfast was good, great walkable location with onsite free parking!"
United States
Lori M
The price is Rp2.111.896
Rp2.386.442 total
includes taxes & fees
7 Dec - 8 Dec
TownePlace Suites by Marriott Louisville North
Courtyard

18. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2.1 km from Kentucky Science Center
9.2 out of 10, Wonderful, (733 reviews)
"Great location, helpful staff, and nice clean rooms,"
United States
Kevin
The price is Rp2.605.279
Rp3.065.371 total
includes taxes & fees
21 Nov - 22 Nov
AC Hotel Louisville Downtown
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

19. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Kentucky Science Center
9.0 out of 10, Wonderful, (4,514 reviews)
"Great place to stay!!!"
United States
Shun
The price is Rp2.347.683
Rp2.762.285 total
includes taxes & fees
1 Dec - 2 Dec
Galt House Hotel Trademark Collection by Wyndham
A building with a sign reading "Embassy Suites."

20. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Kentucky Science Center
9.0 out of 10, Wonderful, (1,392 reviews)
"Enjoyed my whole stay, staff was friendly and helpful"
United States
Ernest P
The price is Rp2.224.409
Rp2.617.239 total
includes taxes & fees
23 Nov - 24 Nov
Embassy Suites Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Kentucky Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
An outdoor patio area with round tables and chairs, surrounded by potted plants and a brick chimney.
Market Street Inn
3.5 star property
9.8
Exceptional
127 reviews
View
A restaurant with a high ceiling, exposed brick walls, hanging plants, and a variety of seating arrangements.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
520 reviews
View
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
4.5 star property
9.4
Exceptional
1,483 reviews
View
An outdoor patio area with seating, a fire pit, and a pergola with string lights.
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,004 reviews
View
A modern interior with leather sofas, a bookshelf, and a decorative wall with 'The Grady' sign.
The Grady
4.0 star property
9.4
Exceptional
1,004 reviews
View

Other attractions near Kentucky Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
See properties

Top Kentucky Science Center Hotel Reviews

An outdoor patio area with seating, a fire pit, and a pergola with string lights.
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
Downtown Louisville

10/10 Excellent

We were directed to the best car park nearby which was on the same block. Staff really friendly and the room was excellent. Would recommend this hotel if you are in visiting
United Kingdom
Stephen
Reviewed April 18, 2026
Homewood Suites by Hilton Louisville Downtown, KY

Frequently Asked Questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.