Santa Ana Travel Guide

Antigua Guatemala

A white colonial church with ornate architecture and a large wooden door.

Things to do


Top hotels in Santa Ana

Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
The price is Rp1.601.321 per night from 7 Dec to 8 Dec
Rp1.601.321
per night
7 Dec - 8 Dec
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ...
Barceló Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is Rp6.288.641 per night from 9 Nov to 10 Nov
Rp6.288.641
per night
9 Nov - 10 Nov
Stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa and 2 restaurants. Our guests praise the helpful staff and the property ...
9.4/10 Exceptional! (1,194 reviews)
"Would stay there over and over. Resort was amazing and well secured and beautifully kept property"

Reviewed on 7 Nov 2026

Hotel Museo Spa Casa Santo Domingo
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
The price is Rp2.290.972 per night from 6 Dec to 7 Dec
Rp2.290.972
per night
6 Dec - 7 Dec
Stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ...
Wyndham Garden Guatemala City
Adriatika Hotel & Residence

Adriatika Hotel & Residence

4.5 out of 5
4 av 20-44 Zona 14 Guatemala City Guatemala
The price is Rp2.017.574 per night from 5 Dec to 6 Dec
Rp2.017.574
per night
5 Dec - 6 Dec
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
Adriatika Hotel & Residence
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is Rp3.708.245 per night from 9 Nov to 10 Nov
Rp3.708.245
per night
9 Nov - 10 Nov
Stay at this spa hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
Hotel Camino Real Antigua
Hotel Biltmore Guatemala

Hotel Biltmore Guatemala

3.5 out of 5
15 Calle 0-31, Zona 10 Guatemala City Guatemala
The price is Rp1.595.450 per night from 15 Nov to 16 Nov
Rp1.595.450
per night
15 Nov - 16 Nov
Stay at this business-friendly hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their ...
9.4/10 Exceptional! (1,019 reviews)
"Buena, aunque en el baño había mucho pelo"

Reviewed on 7 Nov 2026

Hotel Biltmore Guatemala
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.



Santa Ana Travel Guide