Search Hotels in Santa Ana, Antigua Guatemala

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Check prices for these dates

Tonight
8 Nov - 9 Nov
Tomorrow
9 Nov - 10 Nov
Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

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Our top choices for Santa Ana hotels

A two-story building with yellow walls, a balcony with purple flowers, and multiple windows with metal bars.

1. Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (17 reviews)
"Beautiful place to stay at!"
United States
Nery
The price is Rp2.036.370
Rp2.484.371 total
includes taxes & fees
9 Nov - 10 Nov
Villas Santa Ana-Ricardo
A stone-walled corridor with steps leading to a wooden door, surrounded by lush greenery and potted plants.

2. Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo
4.5 star property
Barrio de La Concepción, 1.1 km from Santa Ana
9.4 out of 10, Exceptional, (1,194 reviews)
"Great stay. Spa is amazing"
United States
Julio
The price is Rp6.288.641
Rp7.892.954 total
includes taxes & fees
9 Nov - 10 Nov
Hotel Museo Spa Casa Santo Domingo
A cobblestone courtyard with outdoor seating and umbrellas, surrounded by greenery and a building with a tiled roof.

3. Hotel Camino Real Antigua

Hotel Camino Real Antigua
4.0 star property
Historic Center, 1.4 km from Santa Ana
9.6 out of 10, Exceptional, (1,002 reviews)
"Everything was close to.. very nice staff and the property was amazing."
United States
Stephanie
The price is Rp3.708.245
Rp4.976.284 total
includes taxes & fees
9 Nov - 10 Nov
Hotel Camino Real Antigua
A garden pathway leading to a building with a green lawn and a clear blue sky.

4. Hotel Soleil La Antigua

Hotel Soleil La Antigua
4.0 star property
1.8 km from Santa Ana
8.8 out of 10, Excellent, (1,000 reviews)
"Really nice place to stay"
United States
Donny Guyvan Caserez
The price is Rp2.267.948
Rp2.766.897 total
includes taxes & fees
9 Dec - 10 Dec
Hotel Soleil La Antigua
An outdoor pool area with wooden decking, surrounded by lush greenery and potted plants.

5. Porta Hotel Antigua

Porta Hotel Antigua
4.5 star property
1.1 km from Santa Ana
9.4 out of 10, Exceptional, (1,000 reviews)
"Very nice property, location was great and amenities were excellent."
United States
Oscar
The price is Rp3.514.597
Rp4.287.809 total
includes taxes & fees
9 Nov - 10 Nov
Porta Hotel Antigua
A bathroom with patterned tiles, a glass shower enclosure, and a towel rack.

6. Los Pasos Boutique Hotel & Spa

Los Pasos Boutique Hotel & Spa
4.5 star property
0.7 km from Santa Ana
9.4 out of 10, Exceptional, (1,001 reviews)
"Nice hotel friendly staff and helpful"
United States
Hilda
The price is Rp2.903.527
Rp3.650.837 total
includes taxes & fees
6 Dec - 7 Dec
Los Pasos Boutique Hotel & Spa
A courtyard with a fountain, stone pathway, and seating area surrounded by greenery.

7. El Convento Boutique Hotel

El Convento Boutique Hotel
4.0 star property
Historic Center, 1.5 km from Santa Ana
9.4 out of 10, Exceptional, (955 reviews)
"What a beautiful hotel!"
United States
Kristen
The price is Rp4.392.914
Rp5.630.744 total
includes taxes & fees
9 Dec - 10 Dec
El Convento Boutique Hotel
A covered outdoor seating area with wicker furniture and hanging lights.

8. Ciel-Luxe Hotels

Ciel-Luxe Hotels
3.5 star property
Historic Center, 1.4 km from Santa Ana
8.8 out of 10, Excellent, (475 reviews)
"I had a great stay at Ciel Luxe Hotel! The room was clean and comfortable, the staff was friendly, and the location was convenient. I’d definitely stay here again!"
United States
Corey
The price is Rp1.533.244
Rp1.870.557 total
includes taxes & fees
10 Nov - 11 Nov
Ciel-Luxe Hotels
A covered outdoor area with stone flooring, potted plants, and a wooden pergola.

9. San Rafael Hotel

San Rafael Hotel
4.0 star property
Historic Center, 1.5 km from Santa Ana
9.8 out of 10, Exceptional, (502 reviews)
"We loved it!! The location is great. The room was amazing, the breakfast, the staff… everything was perfect."
Mexico
Francisco Benjamin Macias
The price is Rp3.745.128
Rp4.623.323 total
includes taxes & fees
1 Dec - 2 Dec
San Rafael Hotel
A covered outdoor seating area with a sofa, coffee table, and chairs, surrounded by potted plants and a stone wall.

10. Casa Santa Rosa Hotel Boutique

Casa Santa Rosa Hotel Boutique
3.5 star property
Historic Center, 1.4 km from Santa Ana
9.6 out of 10, Exceptional, (418 reviews)
"Delicious breakfast, nive place, close to everything, I really enjoyed staying there"
United States
Ligia
The price is Rp2.847.751
Rp3.474.256 total
includes taxes & fees
9 Nov - 10 Nov
Casa Santa Rosa Hotel Boutique
A conservatory with a large window, a stone bench, and two chairs with cushions.

11. Meson Panza Verde

Meson Panza Verde
4.0 star property
1.1 km from Santa Ana
9.2 out of 10, Wonderful, (516 reviews)
"Great place to stay"
United States
Mauricio
The price is Rp2.497.368
Rp3.046.789 total
includes taxes & fees
18 Nov - 19 Nov
Meson Panza Verde
A spacious courtyard with red chairs and tables, surrounded by lush greenery and potted plants.

12. El Carmen Hotel

El Carmen Hotel
3.0 star property
Historic Center, 1.3 km from Santa Ana
9.0 out of 10, Wonderful, (961 reviews)
"The breakfast and staff are incredible! Great location!"
United States
Jennifer
The price is Rp1.987.937
Rp2.425.283 total
includes taxes & fees
16 Nov - 17 Nov
El Carmen Hotel
A rooftop terrace with outdoor seating, a fire feature, and a view of a mountain.

13. Las Cruces Boutique Hotel

Las Cruces Boutique Hotel
4.0 star property
Historic Center, 1.4 km from Santa Ana
9.8 out of 10, Exceptional, (292 reviews)
"Beautiful rooms, very attentive staff, and delicious breakfast!"
United States
Miria
The price is Rp5.087.531
Rp6.206.788 total
includes taxes & fees
11 Nov - 12 Nov
Las Cruces Boutique Hotel
A covered walkway with wooden pillars and tropical plants.

14. Good Hotel Antigua Guatemala, a Member of Design Hotels

Good Hotel Antigua Guatemala, a Member of Design Hotels
4.0 star property
0.8 km from Santa Ana
9.4 out of 10, Exceptional, (571 reviews)
"The hotel was very wonderful!! Saul Bistro connects to the hotel which was amazing and convenient. The staff was the best!! I can’t say enough great things about this place"
United States
Brandon Jordani
The price is Rp4.732.237
Rp5.773.329 total
includes taxes & fees
9 Dec - 10 Dec
Good Hotel Antigua Guatemala, a Member of Design Hotels
A lobby with a central reception desk, potted cacti, a chandelier, and a view of the interior through an archway.

15. Mestizo Antigua

Mestizo Antigua
4.0 star property
Historic Center, 1.5 km from Santa Ana
9.4 out of 10, Exceptional, (221 reviews)
"Staff was very friendly and accommodating. Highly recommend!"
United States
Lucy
The price is Rp2.845.943
Rp3.472.050 total
includes taxes & fees
18 Nov - 19 Nov
Mestizo Antigua
A modern, triangular wooden structure with a glass entrance, surrounded by lush greenery.

16. Santo Cielo by Casa Santo Domingo

Santo Cielo by Casa Santo Domingo
3.5 star property
0.9 km from Santa Ana
9.4 out of 10, Exceptional, (580 reviews)
"Great place and staff"
United States
Ricardo
The price is Rp3.842.104
Rp4.908.052 total
includes taxes & fees
10 Nov - 11 Nov
Santo Cielo by Casa Santo Domingo
A hallway with a wooden reception desk, potted plants, and a tiled floor.

17. Casa Noble Hotel

Casa Noble Hotel
3.0 star property
0.9 km from Santa Ana
9.6 out of 10, Exceptional, (263 reviews)
"Fantastic hotel"
Canada
Alysha
The price is Rp1.678.886
Rp2.048.241 total
includes taxes & fees
29 Nov - 30 Nov
Casa Noble Hotel
A corridor with wooden benches, potted plants, and a checkered floor.

18. Hotel Convento Santa Catalina

Hotel Convento Santa Catalina
3.5 star property
Historic Center, 1.6 km from Santa Ana
8.2 out of 10, Very good, (682 reviews)
"Very clean and staff is friendly. Location is amazing!"
United States
Rita
The price is Rp1.201.244
Rp1.465.517 total
includes taxes & fees
8 Dec - 9 Dec
Hotel Convento Santa Catalina
An indoor courtyard with stone flooring, multiple seating areas, and string lights.

19. Hotel Casa Carmina by AHS

Hotel Casa Carmina by AHS
4.0 star property
1.2 km from Santa Ana
8.8 out of 10, Excellent, (390 reviews)
"The staff was wonderful! The location was perfect! The hotel was beautiful! I would definitely recommend! There’s hot water, and WiFi!"
United States
Carlos
The price is Rp1.221.007
Rp1.489.629 total
includes taxes & fees
9 Dec - 10 Dec
Hotel Casa Carmina by AHS
A corridor with arches, tiled flooring, and potted plants.

20. Hotel Las Farolas

Hotel Las Farolas
3.5 star property
1.2 km from Santa Ana
9.2 out of 10, Wonderful, (812 reviews)
"Very nice hotel!"
United States
Katie
The price is Rp2.442.015
Rp2.979.259 total
includes taxes & fees
12 Nov - 13 Nov
Hotel Las Farolas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A two-story building with yellow walls, a balcony with purple flowers, and multiple windows with metal bars.
Villas Santa Ana-Ricardo
3.5 star property
9.0
Wonderful
17 reviews
View
A cozy indoor space with a staircase, seating area, and various plants.
Castillo De Los Gigantes
2.0 star property
8.0
Very good
2 reviews
View
A cobblestone courtyard with outdoor seating and umbrellas, surrounded by greenery and a building with a tiled roof.
Hotel Camino Real Antigua
4.0 star property
9.6
Exceptional
1,002 reviews
View
A stone-walled corridor with steps leading to a wooden door, surrounded by lush greenery and potted plants.
Hotel Museo Spa Casa Santo Domingo
4.5 star property
9.4
Exceptional
1,194 reviews
View
A bathroom with patterned tiles, a glass shower enclosure, and a towel rack.
Los Pasos Boutique Hotel & Spa
4.5 star property
9.4
Exceptional
1,001 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.
A historic yellow archway leading to a clock tower, surrounded by old buildings.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

A town with a prominent volcano in the background.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

A hallway with a wooden reception desk, potted plants, and a tiled floor.
Casa Noble Hotel

Casa Noble Hotel

Casa Noble Hotel
Antigua Guatemala

10/10 Excellent

Beautiful courtyard, safe atmosphere, good breakfast and friendly staff.
United Kingdom
Tor
Reviewed February 28, 2025
Casa Noble Hotel

Frequently Asked Questions

What's it like in Santa Ana?

Travellers to the Santa Ana neighbourhood in Antigua Guatemala will be sure to enjoy their stay.

What's a favourite place to stay in Santa Ana?

Based on our traveller data, Casa Buho B&B is one of the top choices for your stay in Santa Ana. This hotel offers a restaurant and free parking.

How many hotels will I be able to find in Santa Ana?

If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 15 hotels and other accommodation options in Santa Ana.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view top deals in Santa Ana.

What are the top things to see and do in Santa Ana?

House of the Giants, Santa Clara Convent and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, make sure that you visit other sights such as Tanque La Unión or Museo del Hermano Pedro.