A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Defiance Hotel Guide - 4 Stars Hotels in Defiance, St. Louis

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Our top choices for Defiance 4-star hotels

Coffee shop

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,008 reviews)
"Great stay!"
United States
Matiah
The price is Rp2.895.530
Rp3.685.759 total
includes taxes & fees
1 Jul - 2 Jul
Ameristar Casino Resort and Spa
Indoor pool

DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport
4.0 star property
Westport
8.0 out of 10, Very good, (1,001 reviews)
"The restaurant has an amazing salad and the bartender (I forgot his name) is excellent. If I’m ever in St. Louis again I’ll definitely stay there"
United States
RoSalyn
The price is Rp2.266.952
Rp2.629.394 total
includes taxes & fees
21 Jun - 22 Jun
DoubleTree by Hilton St. Louis - Westport
Exterior

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,004 reviews)
"Great place to stay "
United States
Tony
The price is Rp2.429.917
Rp2.830.417 total
includes taxes & fees
8 Jul - 9 Jul
Hilton St. Louis Frontenac
Reception

DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
4.0 star property
Chesterfield
8.8 out of 10, Excellent, (1,002 reviews)
"The front desk staff were very friendly and accommodating!"
United States
Michelle
The price is Rp2.612.706
Rp3.030.425 total
includes taxes & fees
5 Jul - 6 Jul
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Bar (on property)

The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
9.0 out of 10, Wonderful, (147 reviews)
"It was just OK stay."
United States
Greg
The price is Rp2.352.982
Rp2.679.092 total
includes taxes & fees
14 Jun - 15 Jun
The Inn at Elijah McLeans
Lounge

Landing Apartments - Eureka

Landing Apartments - Eureka
4.0 star property
Eureka
Landing Apartments - Eureka
Apartment (2 Bedrooms) | Interior

'the Ruebling House': Bright, Modern, & Renovated!

'the Ruebling House': Bright, Modern, & Renovated!
4.0 star property
Defiance
'the Ruebling House': Bright, Modern, & Renovated!
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Defiance?
To book a 4-star hotel in Defiance that fits your budget, take advantage of Expedia's sort and search filters. Browse the available options during your chosen dates and use our pricing filter to set your maximum rate. You can also list your results by the cheapest retreat first.

  • Search for the lowest price from Rp2.629.394

What's the difference between 5-star and 4-star hotels in Defiance?
Treat yourself to luxury during your Defiance escape by checking in to a 4-star hotel. As well as featuring upscale accommodation, these retreats are typically packed with amenities like complimentary bathrobes, large beds and plenty more. A 5-star hotel will go above and beyond to make your trip an even more indulgent and special one. 24-hour front desk, on-site spas and gourmet dining are a few of the exclusive conveniences and services you'll likely get access to.
Does Defiance have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next dream getaway in Defiance where just about everything is taken care of, from your meals to your room, entertainment and activities. We can also help you find standard 4-star stays in and around this leading destination.