Defiance Hotel Guide - 4 Stars Hotels in Defiance, St. Louis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Defiance 4 Star Hotels

Our top choices for Defiance 4-star hotels

Exterior

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,000 reviews)
"Great room, great amenities!"
United States
Linda or James
The price is Rp2.198.859
Rp2.561.406 total
includes taxes & fees
25 Jan - 26 Jan
Hilton St. Louis Frontenac
Seasonal outdoor pool

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very good, (1,005 reviews)
"Was an amazing hotel to stay at!! Clean spacious and very nice!!! Will stay here again!!"
United States
Darci
The price is Rp3.020.521
Rp3.810.077 total
includes taxes & fees
19 Jan - 20 Jan
Ameristar Casino Resort and Spa
Indoor pool

DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport
4.0 star property
Maryland Heights
8.2 out of 10, Very good, (1,002 reviews)
"Stayed one night felt very safe here"
United States
William
The price is Rp1.965.158
Rp2.279.347 total
includes taxes & fees
23 Jan - 24 Jan
DoubleTree by Hilton St. Louis - Westport
Reception

DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
4.0 star property
Chesterfield
8.6 out of 10, Excellent, (1,000 reviews)
"Great hotel!"
United States
John
The price is Rp2.062.032
Rp2.391.709 total
includes taxes & fees
6 Feb - 7 Feb
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Bar (on property)

The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
8.8 out of 10, Excellent, (134 reviews)
"It was very nice. A great place to stay in a great little town."
United States
Hal
The price is Rp2.276.775
Rp2.592.151 total
includes taxes & fees
15 Feb - 16 Feb
The Inn at Elijah McLeans
Property amenity

Landing Apartments - Eureka

Landing Apartments - Eureka
4.0 star property
Eureka
Landing Apartments - Eureka
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Defiance?
To book a 4-star hotel in Defiance that fits your budget, take advantage of Expedia's sort and search filters. Browse the available options during your chosen dates and use our pricing filter to set your maximum rate. You can also list your results by the cheapest retreat first.

  • Search for the lowest price from Rp2.279.347

What's the difference between 5-star and 4-star hotels in Defiance?
Treat yourself to luxury during your Defiance escape by checking in to a 4-star hotel. As well as featuring upscale accommodation, these retreats are typically packed with amenities like complimentary bathrobes, large beds and plenty more. A 5-star hotel will go above and beyond to make your trip an even more indulgent and special one. 24-hour front desk, on-site spas and gourmet dining are a few of the exclusive conveniences and services you'll likely get access to.
Does Defiance have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next dream getaway in Defiance where just about everything is taken care of, from your meals to your room, entertainment and activities. We can also help you find standard 4-star stays in and around this leading destination.