A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Florida Keys Hotel Guide - 4 Stars Hotels in Florida Keys, United States of America

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Check availability on Florida Keys 4 Star Hotels

Tonight
16 Oct - 17 Oct
Tomorrow
17 Oct - 18 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Florida Keys 4-star hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A spacious living room with large windows, comfortable seating, and decorative plants.
A poolside area with blue chairs and a thatched-roof structure.
A spacious bar area with high ceilings and large windows, offering views of the ocean.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
United States
Manny
Rp3.587.373
Rp4.756.965 total
includes taxes & fees
19 Oct - 20 Oct
Reefhouse Resort & Marina
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.
A child sitting on a beach with sand toys and a green bucket nearby.
An aerial view of a resort with two large swimming pools surrounded by palm trees and lounge chairs.
A beachfront hotel with multiple balconies, a pool, and a beach area with lounge chairs.

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
United States
Alan
Rp4.839.314
Rp6.433.150 total
includes taxes & fees
28 Oct - 29 Oct
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A pool area with lounge chairs and umbrellas, surrounded by palm trees.
A pathway leading to a pool area with palm trees and a sunset view.
An aerial view of a coastal resort with multiple white buildings, a clear turquoise sea, and lush greenery.
A modern living room with a balcony overlooking the sea, furnished with a sofa, chairs, and a dining table.

3. Hawks Cay Resort

Hawks Cay Resort
Marathon
United States
Antonio
Rp3.617.915
Rp5.449.228 total
includes taxes & fees
25 Oct - 26 Oct
Hawks Cay Resort
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
An aerial view of a resort with a swimming pool, palm trees, and a dock.
A resort pool with palm trees, beach chairs, and umbrellas.
A hotel room with a bed, a sofa, a coffee table, a desk with a lamp, and a view of the ocean.

4. Amara Cay Resort

Amara Cay Resort
Matecumbe
United States
Danielle
Rp2.772.767
Rp4.431.169 total
includes taxes & fees
19 Oct - 20 Oct
Amara Cay Resort
A balcony with wicker chairs, a small table with drinks, and a view of the beach and ocean.
A coastal resort with a beach, a swimming pool, and multiple buildings.
A beach with palm trees, a clear blue sky, and a calm sea.
An outdoor dining area with round tables and chairs, a thatched roof, and a view of the sea.

5. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
United States
Liosbel
Rp4.290.770
Rp6.138.922 total
includes taxes & fees
2 Nov - 3 Nov
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A wooden pier leading to a beach with palm trees and a row of beach huts.
A beachside patio with wooden furniture, a thatched roof, and a view of the ocean.
A bar area with a wooden counter, bar stools, and potted plants.

6. Islander Resort

Islander Resort
Matecumbe
United States
Steven
Rp3.731.104
Rp5.509.119 total
includes taxes & fees
18 Oct - 19 Oct
Islander Resort
An aerial view of a resort with a large pool, palm trees, and a beach.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.
A beach with clear water, a wooden pier, and lounge chairs under a tree.

7. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
United States
Jorge
Rp5.004.702
Rp6.619.212 total
includes taxes & fees
1 Nov - 2 Nov
Playa Largo Resort & Spa, Autograph Collection
A swimming pool surrounded by palm trees and lounge chairs.
A spacious living room with a wooden coffee table, a striped sofa, and a television on a wooden cabinet.
A beach scene with a wooden deck, palm trees, and a gazebo-like structure.
An aerial view of a resort with a central swimming pool, surrounded by lush greenery and palm trees, with a view of the ocean.

8. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
Marathon
United Kingdom
Stuart
Rp3.429.746
Rp5.006.855 total
includes taxes & fees
15 Nov - 16 Nov
Tranquility Bay Beachfront Hotel and Resort
Pool
Exterior
View from room
Lobby

9. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
United States
Rick
Rp2.927.123
Rp3.968.020 total
includes taxes & fees
25 Oct - 26 Oct
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
A row of beachside cottages with colorful exteriors, each with a beach chair and umbrella.
A resort with a pool surrounded by palm trees and a view of the ocean.
A beach resort with palm trees, a thatched hut, and a purple building with a window.
A beach with colorful buildings, kayaks, and lounge chairs.

10. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
United States
Brianne
Rp2.772.767
Rp4.431.170 total
includes taxes & fees
15 Nov - 16 Nov
La Siesta Resort & Villas
A wooden deck with a pool and chairs overlooking a beach with palm trees.
A hotel room with a sofa, a desk, a chair, a TV, and a balcony with curtains.
A pool area with palm trees and a view of the ocean.
A beach with a wooden walkway leading to the water, palm trees, and a clear sky.

11. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
United States
Tiffany
Rp3.298.260
Rp4.571.567 total
includes taxes & fees
15 Nov - 16 Nov
Grassy Flats Resort & Beach Club
A resort pool with palm trees and lounge chairs, surrounded by a beachfront.
A modern kitchen with white cabinetry, a stainless steel oven, and a large island with a bowl of fruit.
A modern living room with a sofa, chairs, a dining table, a TV, and a view of the ocean.
An aerial view of a resort island with a large building, a swimming pool, and a boat docked nearby.

12. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
United States
Gabriela
Rp8.233.542
Rp10.372.828 total
includes taxes & fees
16 Nov - 17 Nov
Villas At Hawks Cay Resort
A large hotel with a pool, multiple balconies, and palm trees.
A large, two-story hotel with a swimming pool in front.
A beach with clear water and gentle waves.
A beachside wedding setup with wicker chairs and a white canopy, palm trees, and a sunset view.

13. Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
Marathon
United States
Chardell
Marlin Bay Resort & Marina
A covered outdoor area with a wooden deck, white railings, and a view of the ocean.
An aerial view of a coastal resort with multiple buildings, a marina, and clear blue waters.
A spacious dining area with a long table, wicker chairs, and hanging wicker lamps.
A poolside area with lounge chairs and palm trees.

14. Waterfront Luxury Villa

Waterfront Luxury Villa
Marathon Shores
Waterfront Luxury Villa
Interior
A modern kitchen with white cabinetry, a built-in oven, and a large island with stools.
A modern kitchen with a central island, bar stools, and a ceiling fan.
A modern kitchen with white cabinets, a microwave, and a dishwasher. There are three bar stools and a large window overlooking the ocean.

15. Florida Keys Getaway w/ Stunning Ocean Views

Florida Keys Getaway w/ Stunning Ocean Views
Long Key
Florida Keys Getaway w/ Stunning Ocean Views
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL
Rp3.569.662
Rp5.327.676 total
18 Oct - 19 Oct
includes taxes & fees
9.2/10 Wonderful! (1,480 reviews)
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL
Rp3.697.022
Rp5.232.381 total
18 Oct - 19 Oct
includes taxes & fees
9.2/10 Wonderful! (1,292 reviews)
Isla Bella Beach Resort & Spa
The Islands of Islamorada

The Islands of Islamorada

82779 Old Hwy Islamorada FL
Rp9.363.636
Rp11.710.196 total
18 Oct - 19 Oct
includes taxes & fees
The Islands of Islamorada
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colourful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys
A beach with a historic brick fort, a small seaplane, and a group of people walking along the shore.

Top Florida Keys Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"Staff was very attentive and provided great service! Checked out at 11:00am and were allowed to stay until late afternoon. They had showers and towels we could use next to the Dry Rocks bar and grill to clean up before needing to drive back to Miami for the evening."
Terry 3-night trip
Posted less than an hour ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

10/10 Excellent
"As soon as we"
Stephen 4-night trip
Posted 3 days ago
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
Based on reviews by Expedia customers, La Concha Key West is among the best 4-star hotels in Florida Keys. Situated in Key West, it has a swimming pool and beauty services. Opal Key Resort & Marina, Key West is another leading option here. Also rated 4 stars and offering a spa tub and a terrace, it promises a comfortable stay.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To lock in a 4-star hotel in Florida Keys that matches your budget, take advantage of Expedia's search and sort filters. Check out what's available during your chosen dates and use our pricing filter to set your maximum rate. You can also list your results by the most budget-friendly escape first.
  • Search for the lowest price from Rp5.232.381
What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a fantastic option for your Florida Keys escape. These types of stays generally come with lots of handy amenities that make it easy to unpack and recharge — think pillowtop mattresses, gyms and restaurants. Or get a taste of the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. 24-hour front desk, complimentary toiletries and world-class dining are typically featured at these plush properties.

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