A historic stone fortress with a central dome and surrounding walls.

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Check availability on Colon Luxury Hotels

Tonight
27 Sept - 28 Sept
Tomorrow
28 Sept - 29 Sept
Next weekend
2 Oct - 4 Oct
In two weeks
9 Oct - 11 Oct

Our top choices for Colon luxury hotels

A rooftop pool area with lounge chairs and a view of a port with cranes.
A lobby with a curved ceiling, a reception desk, seating area, and a TV screen.
A spacious lobby with a reception desk, comfortable seating, and a glass wall offering a view of the street.
A gym with various exercise equipment, large windows, and a view of the outside.

1. Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
Barrio Sur
Rp2.080.150
Rp2.288.165 total
includes taxes & fees
10 Oct - 11 Oct
Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
A poolside area with lounge chairs and a covered seating area, reflecting the pool and surrounding structures.
A spacious dining area with large windows offering a view of lush greenery.
An aerial view of a resort with a central building, a circular driveway, and surrounding greenery.
A room with a large glass window, a wooden chair, and a glass table with a plant.

2. Summit Rainforest Golf Resort & All Inclusive

Summit Rainforest Golf Resort & All Inclusive
Panama City
Rp3.844.168
Rp4.228.585 total
includes taxes & fees
4 Oct - 5 Oct
Summit Rainforest Golf Resort & All Inclusive
A hotel entrance with a central water feature, seating areas, and potted plants.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.
A pool with a central water feature, surrounded by seating areas and potted plants.

3. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
  • Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
Rp4.812.863
Rp5.294.149 total
includes taxes & fees
15 Oct - 16 Oct
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A resort with a large swimming pool, thatched-roof structures, and palm trees.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.
A well-maintained garden with a pathway leading to a gazebo, surrounded by palm trees and a view of the sea.
An outdoor dining area with tables and chairs, overlooking a body of water and a forested island.

4. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
Rp4.982.405
Rp4.982.405 total
includes taxes & fees
1 Oct - 2 Oct
Dreams Playa Bonita Panama - All Inclusive
A poolside area with lounge chairs and a view of the ocean.
A terrace with seating and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.

5. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
Rp4.998.518
Rp5.498.370 total
includes taxes & fees
24 Oct - 25 Oct
JW Marriott Panama
A buffet with various food items and a decorative plant.
A spacious lobby with a high ceiling, a glass railing on the upper level, and a seating area with modern furniture.
A gym with treadmills, weight machines, and a red carpet.
A spa area with a hot tub, candles, and a curved bench.

6. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
Rp3.303.104
Rp3.633.414 total
includes taxes & fees
3 Oct - 4 Oct
Sheraton Grand Panama
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.
A buffet setup with various dishes and utensils.
A spacious lobby with high ceilings, large windows, and modern lighting fixtures.
A modern hotel lobby with a glass railing, seating area, and contemporary lighting fixtures.

7. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
  • Luxury redefined in Panama City with rooftop pool, premium dining, and concierge services to elevate your urban escape.
Rp3.025.607
Rp3.328.167 total
includes taxes & fees
10 Oct - 11 Oct
Marriott Panama Hotel
A hotel with a pool, beach, and palm trees.
A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.
A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.

8. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
  • Oceanfront luxury beckons with private beach, indulgent spa services, and refined dining at this beachfront Panama retreat.
Rp3.689.808
Rp4.058.789 total
includes taxes & fees
6 Oct - 7 Oct
The Westin Playa Bonita Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A modern interior with a central seating area, potted plants, and a staircase.
A modern building with a sign reading 'HYATT REGENCY.'
A spacious hotel lobby with modern furniture, large windows, and a city view.

9. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
  • Indulgence awaits in this 4.5-star Panama City sanctuary featuring a full-service spa, outdoor pool, and elegant dining near Via Espana.
Rp3.347.861
Rp3.682.647 total
includes taxes & fees
3 Oct - 4 Oct
Hyatt Regency Panama City
A buffet with various food items including fruits, juices, and cheeses.
A modern hotel lobby with a sectional sofa, a glass coffee table, and a vibrant green wall mural.
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.
A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.

10. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
Rp1.811.784
Rp1.992.962 total
includes taxes & fees
16 Oct - 17 Oct
Courtyard by Marriott Panama Metromall
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Top Colon Hotel Reviews

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

10/10 Excellent
"The property was amazing. The tours were fantastic. The hot tub was closed while we were there which was a disappointment."
Catherine 2-night trip
Posted 12 hours ago
Gamboa Rainforest Reserve
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"I would definitely recommend this hotel to anyone. The hotel is clean, the staff are well trained with excellent customer service skills and the breakfast is excellent. I am definitely going back. The hotel is always in the middle of city which seals the deal"
Shaquille 3-night trip
Posted 18 hours ago
Hotel Riu Plaza Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"El hotel muy limpio, la atención excelente, el agua de la piscina caliente. Fui con mis 2 hijas y mi esposa y el lugar cumple con todo lo ofrecido"
Andres Fernando Charro 4-night trip
Posted 2 days ago
Decapolis Hotel Panama City

Frequently asked questions

Are you looking for a luxury hotel for your Colon holiday?
Use Expedia to arrange your flight to Panama City (PAC-Marcos A. Gelabert Intl.) airport or Balboa (BLB-Panama Pacifico Intl.) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Colon offers. Colon has some interesting things to see and do including Colon 2000 and Colon Free Zone, so you might want to take in the local sights during your visit.
What's the best luxury place to stay in Colon?
Sand Diamond Hotel is a luxury hotel with ski-in/ski-out access and a casino, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in Colon?
Planning for the weather is an important factor for making your trip to Colon a success, especially when you're splurging. The hottest months are usually May and September, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Colon are November, July, August and October, with each month seeing an average of 350 mm of rainfall.
What's there to see and do in Colon?
Take in the sights and attractions that Colon offers with a visit to Colon 2000, Colon Free Zone and Gamboa Rainforest Resort. If you have extra time while you're in the area, you might want to see Limon Bay and Fort San Lorenzo.
How can I get around Colon?
It's easier to get around town in style when you know your options. If you want to venture outside the area, hop aboard a train at Colon Atlantic Passenger Station.