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8 Nov - 9 Nov
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13 Nov - 15 Nov
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Our top choices for Medical Center District hotels

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

1. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,530 reviews)
"Nice overnight stay."
United States
Sharon
The price is Rp1.627.829
Rp1.942.651 total
includes taxes & fees
12 Nov - 13 Nov
Drury Inn & Suites San Antonio Northwest Medical Center
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

2. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,776 reviews)
"Great place to stay"
United States
Gilbert
The price is Rp1.606.303
Rp1.916.962 total
includes taxes & fees
9 Nov - 10 Nov
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
A spacious lobby with a central staircase, seating area, and large windows.

3. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,194 reviews)
"Room was clean, very friendly staff"
Canada
Hsiao Tung
The price is Rp1.685.940
Rp2.022.493 total
includes taxes & fees
8 Dec - 9 Dec
San Antonio Marriott Northwest Medical Center
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

4. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,111 reviews)
"The breakfast was good and staff was very helpful."
United States
Tina
The price is Rp1.700.366
Rp1.989.427 total
includes taxes & fees
15 Nov - 16 Nov
Fairfield Inn & Suites by Marriott San Antonio Medical Center
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

5. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,002 reviews)
"Great property, nice rooms"
United States
Francisca
The price is Rp1.611.730
Rp1.923.439 total
includes taxes & fees
26 Nov - 27 Nov
Courtyard by Marriott Medical Center San Antonio
A modern kitchen with a large window, wooden counter, and two bar stools.

6. Park Inn by Radisson, Medical Center

Park Inn by Radisson, Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (1,001 reviews)
"Went with my partner, away from the bustle but still close to everything. Great little place."
United States
Jaime
The price is Rp1.122.422
Rp1.313.234 total
includes taxes & fees
1 Dec - 2 Dec
Park Inn by Radisson, Medical Center
A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.

7. Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (405 reviews)
"It was clean and cheap. I’d stay again but the mattress was old and you could hear and feel the springs sheets and room were clean."
United States
seth
The price is Rp940.628
Rp1.100.535 total
includes taxes & fees
9 Nov - 10 Nov
Studio 6 San Antonio, Tx - Northwest Medical Center
A modern bedroom with a large bed, bedside tables, a desk, and a chair.

8. Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,002 reviews)
"Inexpensive. Above expectations. Quiet, cool, staff friendly."
United States
robert
The price is Rp832.998
Rp1.066.527 total
includes taxes & fees
9 Nov - 10 Nov
Motel 6 San Antonio, TX - Northwest Medical Center
A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.

9. Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (321 reviews)
"It’s. Nice place to stay, it’s big and comfortable."
United States
Jose Rolando
The price is Rp1.253.568
Rp1.466.837 total
includes taxes & fees
9 Nov - 10 Nov
Atria Inn & Suites
A hotel room with two beds, a TV, a desk, and a kitchenette in the background.

10. Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (1,000 reviews)
"Good for a short stay traveling through the SA area."
United States
Jerron
The price is Rp904.269
Rp1.115.333 total
includes taxes & fees
9 Nov - 10 Nov
Studio 6 Extended Stay - San Antonio, TX - Medical Center
A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.

11. OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (251 reviews)
"great place to stay close to the hospital. Would stay there again"
United States
Melanie
The price is Rp1.028.721
Rp1.306.568 total
includes taxes & fees
22 Nov - 23 Nov
OYO Inn & Suites Medical Center San Antonio
A hotel room with a large bed, a desk with a chair, a television on a stand, and a mirror on the wall.

12. Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.2 out of 10, (579 reviews)
"Extreme need of grab bars by tub. Tub is on an elevated platform. Very difficult to get out."
United States
David
The price is Rp795.916
Rp949.846 total
includes taxes & fees
9 Nov - 10 Nov
Flex Studios
A modern bar area with a central island, bar stools, and a kitchen counter with appliances.

13. Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center
3.0 star property
3.7 km from Medical Center District
8.4 out of 10, Very good, (1,083 reviews)
"Loved the room and how clean the property was. Would stay here again."
United States
Muri
The price is Rp1.693.130
Rp2.042.650 total
includes taxes & fees
26 Nov - 27 Nov
Hyatt Place San Antonio-Northwest/Medical Center
A modern lobby with a sofa, patterned chairs, a central ottoman, and a chandelier.

14. Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport
3.0 star property
9 km from Medical Center District
9.4 out of 10, Exceptional, (2,331 reviews)
"Great stay"
United States
garry
The price is Rp2.061.965
Rp2.460.749 total
includes taxes & fees
15 Nov - 16 Nov
Drury Plaza Hotel San Antonio Airport
A modern hotel with a prominent sign reading "LA QUINTA".

15. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
9 km from Medical Center District
9.2 out of 10, Wonderful, (1,171 reviews)
"Great stay for Lackland Air Force Base."
United States
Lakesha
The price is Rp1.881.256
Rp2.201.069 total
includes taxes & fees
29 Nov - 30 Nov
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
A hotel with a modern design, featuring a covered parking area and multiple parking spaces.

16. Best Western Medical Center North Inn & Suites Near Six Flags

Best Western Medical Center North Inn & Suites Near Six Flags
2.5 star property
Northwest Side, 5.2 km from Medical Center District
8.2 out of 10, Very good, (1,615 reviews)
"Good budget business hotel."
United States
Vijay
The price is Rp1.203.099
Rp1.407.625 total
includes taxes & fees
15 Nov - 16 Nov
Best Western Medical Center North Inn & Suites Near Six Flags
A buffet with various food items, including omelets and other dishes, served in metal containers.

17. Holiday Inn Express San Antonio-Airport by IHG

Holiday Inn Express San Antonio-Airport by IHG
2.5 star property
8.9 km from Medical Center District
9.4 out of 10, Exceptional, (1,007 reviews)
"The rooms were very clean and beds were so comfortable."
United States
Lori
The price is Rp1.826.989
Rp2.180.329 total
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express San Antonio-Airport by IHG
A modern kitchen with a central island, built-in appliances, and a coffee station.

18. Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport
3.0 star property
Uptown Central, 9.2 km from Medical Center District
8.6 out of 10, Excellent, (2,053 reviews)
"Good place to stay by the airport."
United States
Antonio
The price is Rp1.476.062
Rp1.761.532 total
includes taxes & fees
22 Nov - 23 Nov
Wyndham Garden San Antonio Airport
A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

19. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
2.5 star property
Uptown Central, 9.3 km from Medical Center District
9.0 out of 10, Wonderful, (2,387 reviews)
"Great location near the airport."
United States
Elsa
The price is Rp1.429.935
Rp1.706.484 total
includes taxes & fees
12 Nov - 13 Nov
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
A spacious dining area with multiple tables and chairs, a bar area, and a television mounted on the wall.

20. Hampton Inn & Suites San Antonio Northwest/Medical Center

Hampton Inn & Suites San Antonio Northwest/Medical Center
2.5 star property
Northwest Side, 4.7 km from Medical Center District
8.6 out of 10, Excellent, (1,013 reviews)
"Great place clean room good breakfast nice staff"
United States
Ioana
The price is Rp1.499.397
Rp1.823.117 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites San Antonio Northwest/Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in Medical Center District

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

Drury Inn & Suites San Antonio Northwest Medical Center

3.0 star property
Medical Center District
View
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3.0 star property
Medical Center District
View
A spacious lobby with a central staircase, seating area, and large windows.

San Antonio Marriott Northwest Medical Center

3.5 star property
Medical Center District
View
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

Fairfield Inn & Suites by Marriott San Antonio Medical Center

3.0 star property
Medical Center District
View
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

Courtyard by Marriott Medical Center San Antonio

3.0 star property
Medical Center District
View
9.2
Wonderful
1,530 reviews
8.4
Very good
3,776 reviews
8.6
Excellent
1,194 reviews
9.0
Wonderful
1,111 reviews
8.8
Excellent
1,002 reviews
The price is Rp1.627.829
Rp1.942.651 total
includes taxes & fees
12 Nov - 13 Nov
The price is Rp1.606.303
Rp1.916.962 total
includes taxes & fees
9 Nov - 10 Nov
The price is Rp1.685.940
Rp2.022.493 total
includes taxes & fees
8 Dec - 9 Dec
The price is Rp1.700.366
Rp1.989.427 total
includes taxes & fees
15 Nov - 16 Nov
The price is Rp1.611.730
Rp1.923.439 total
includes taxes & fees
26 Nov - 27 Nov
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • No WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Hotels recommended for families in Medical Center District

A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,002)
The price is Rp1.611.730
Rp1.923.439 total
includes taxes & fees
26 Nov - 27 Nov
Courtyard by Marriott Medical Center San Antonio

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.
A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

A riverside walkway adorned with colorful umbrellas and festive lights.

Uptown Central

If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

A riverside walkway with colorful umbrellas, a stone bridge, and historic buildings.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

A historic stone building with a large wooden door, arched windows, and ornate columns.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

Top Medical Center District Hotel Reviews

A modern bar area with wooden bar counters, black bar stools, and pendant lighting.
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
Medical Center District

10/10 Excellent

A nice property and would stay again. Some amenities in walking distance
United Kingdom
Andrew
Reviewed October 25, 2024
Courtyard by Marriott Medical Center San Antonio

Frequently Asked Questions

What is Medical Center District like?

Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Consider a visit to Cinemark San Antonio 16 as part of your Medical Center District travel plans.

What's a favourite hotel to stay in Medical Center District?

Based on our traveller data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include Drury Inn & Suites San Antonio Northwest Medical Center and Courtyard by Marriott Medical Center San Antonio.

How many hotels will I be able to find in Medical Center District?

Expedia has 124 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.

What can I see and do in this San Antonio neighbourhood?

Cinemark San Antonio 16 is an attraction you might want to check out while you're in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.