Medical Center District Holidays

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Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
A boat tour on a canal with a bridge in the background.

Downtown San Antonio

4 out of top 10 points of interest in this area
4.5/5(42 area reviews)

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Find hotels in Downtown San Antonio

Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is Rp1.596.624 per night from 9 Jul to 10 Jul
Rp1.596.624
Rp1.887.181 total
9 Jul - 10 Jul
includes taxes & fees
8.4/10 Very good! (3,474 reviews)
"The staff were friendly and helpful. Our room was clean. Enjoyed the complimentary breakfast. Would definitely recommend and we look forward to our next stay."

Reviewed on 7 Jul 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is Rp1.577.206 per night from 8 Aug to 9 Aug
Rp1.577.206
Rp1.874.109 total
8 Aug - 9 Aug
includes taxes & fees
8.6/10 Excellent! (1,112 reviews)
"I rated the experience a 4 overall, but it's really closer to a 3.5. Upon arrival, there was some trash around the front entrance, but it was very windy that day. However, after staying all weekend, it appeared to be an ongoing issue. Once inside, the lobby and all other areas appeared to be consistently ..."

Reviewed on 8 Jul 2026

San Antonio Marriott Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W San Antonio TX
Fully refundableReserve now, pay when you stay
The price is Rp1.618.020 per night from 26 Jul to 27 Jul
Rp1.618.020
Rp1.912.645 total
26 Jul - 27 Jul
includes taxes & fees
9.2/10 Wonderful! (1,382 reviews)
"Friendly informative staff. Clean room. Would stay here again."

Reviewed on 6 Jul 2026

Drury Inn & Suites San Antonio Northwest Medical Center
See all 4,863 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Medical Centre District holiday package cost?
Starting from just , a holiday package is your passport to low-priced travel. Create your own Medical Centre District adventure by picking from our huge range of airfares, hotels and rental cars.
How do I get a cheap travel package to Medical Centre District?
It's as simple as bundling. Hotels, rental cars and flights — combine whatever you need into a Medical Centre District holiday package and save. Score even better deals when you include extras such as activities or tours to your booking. But that's not the only good part. You have the freedom to customize your holiday your own way. We offer over 550 airlines and 1,000,000 properties throughout the world, so that everyone has a chance to travel and fulfil those holiday dreams.
Where should I stay in Medical Centre District?
Make a reservation just around the corner from Six Flags Fiesta Texas, one of this area's most well-known attractions. It's the ideal spot for serious sightseers.
What are the top hotels in Medical Centre District?
Amazing, Contemporary, Beautiful and Fairfield Inn & Suites by Marriott San Antonio Medical Centre are two of the most well-known hotels in Medical Centre District. Why not take a look at the amenities and rates at each and then make up your mind?
How far in advance should I book my Medical Centre District holiday?
It all depends on the airline, but it's usually possible to look up international fares on Expedia up to 12 months in advance. While it's generally recommended to book ahead of time, lucky customers will sometimes nab a cheaper ticket just weeks before the date of departure.
What does an Expedia Medical Centre District travel package include?
Flights, car rentals and hotels — we connect you to the very best deals. All you'll have to do is figure out your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it easy to customize an exciting Medical Centre District holiday.
What should I know before booking a Medical Centre District travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fantastic discounts. You're not limited to hotels, however. Book with us and select from island resorts, city apartments and just about everything in between!
Can I choose my airline with a Medical Centre District Expedia holiday package?
Yes, you're in charge. We have access to over 550 partner airlines globally, so you can tailor your Medical Centre District trip according to your budget and travel needs.
If I'm not able to travel, can I cancel my Medical Centre District holiday package?
Whether it's your hotel or flight, you can cancel or change it. Booked your Medical Centre District holiday package in the last 24 hours? You may be able to make any changes for free. For bookings made more than 24 hours ago, you may be charged a fee by your airline, hotel or car rental company. For more information, head to our Customer Service Portal. We're here to help you every step of the way.

Stay near popular Medical Center District attractions

USAA Corporate Office Headquarters

7.8/10 (7 reviews)
USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.
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Things to do

San Antonio Zoo Any Day Ticket including ZooLights

San Antonio: Zoo Entry & Zoorassic Park Dinosaur Experience

Rp528.448
per adult
96% of travellers recommend
San Antonio: Zoo Entry & Zoorassic Park Dinosaur Experience
SEA LIFE San Antonio

SEA LIFE San Antonio

Rp463.977
per adult
76% of travellers recommend
SEA LIFE San Antonio
Hopscotch San Antonio Immersive Art Experience

Hopscotch San Antonio Immersive Art Experience

Rp428.616
per adult
96% of travellers recommend
Hopscotch San Antonio Immersive Art Experience
See all activities in San Antonio
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.