Search Hotels in Medical Center District, San Antonio

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
31 Dec - 1 Jan
Tomorrow
1 Jan - 2 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical Center District hotels

Lobby
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1011)
"Best hotel!"
United States
Valeria
The price is Rp1.828.962
Rp2.173.340 total
includes taxes & fees
3 Jan - 4 Jan
San Antonio Marriott Northwest Medical Center
Pool
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
2.5 star property
Medical Center District
9.0 out of 10, Wonderful, (1012)
"Everything was great, staff really kind ..."
United States
traci
The price is Rp1.534.560
Rp1.791.599 total
includes taxes & fees
8 Jan - 9 Jan
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Exterior
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1000)
"Clean rooms @ friendly staff!"
United States
LaTishe
The price is Rp1.484.520
Rp1.754.836 total
includes taxes & fees
30 Jan - 31 Jan
Courtyard by Marriott Medical Center San Antonio
Front of property
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3141)
"Great place "
United States
Amado
The price is Rp1.481.184
Rp1.750.733 total
includes taxes & fees
2 Jan - 3 Jan
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Desk, laptop workspace, blackout curtains, free WiFi
Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.2 out of 10, Good, (223)
"Good stay and safe area"
United States
Mario
The price is Rp813.150
Rp949.426 total
includes taxes & fees
4 Jan - 5 Jan
Studio 6 San Antonio, Tx - Northwest Medical Center
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1295)
"Great place to stay and visit "
United States
Harry
The price is Rp1.501.033
Rp1.774.252 total
includes taxes & fees
5 Jan - 6 Jan
Drury Inn & Suites San Antonio Northwest Medical Center
Exterior
OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.2 out of 10, Good, (228)
"Staff was courteous and professional and the room is nice."
United States
Thomas
The price is Rp900.720
Rp1.109.971 total
includes taxes & fees
26 Jan - 27 Jan
OYO Inn & Suites Medical Center San Antonio
Premium bedding, pillow-top beds, in-room safe, desk
SpringHill Suites by Marriott San Antonio Medical Center/NW

SpringHill Suites by Marriott San Antonio Medical Center/NW

SpringHill Suites by Marriott San Antonio Medical Center/NW
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1002)
"good staff. good stay"
United States
Divya
The price is Rp1.684.680
Rp1.991.443 total
includes taxes & fees
2 Jan - 3 Jan
SpringHill Suites by Marriott San Antonio Medical Center/NW
Reception
Park Inn by Radisson

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1000)
"Staff were amazing, and everything else was great too. "
United States
Maximilian
The price is Rp1.012.130
Rp1.181.661 total
includes taxes & fees
23 Jan - 24 Jan
Park Inn by Radisson
Basic Room, Multiple Beds, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets
Flex Studios

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (498)
"heb is nearby. "
United States
Sayeed
The price is Rp690.552
Rp816.295 total
includes taxes & fees
5 Jan - 6 Jan
Flex Studios
Front of property
Atria Inn & Suites

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (275)
"Nice, comfortable space for a reasonable price. "
United States
Cynthia
Atria Inn & Suites
Free daily on-the-go breakfast
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
6.8 out of 10, (1000)
"Clean room and great customer service "
United States
roel
The price is Rp983.619
Rp1.148.375 total
includes taxes & fees
21 Jan - 22 Jan
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Desk, laptop workspace, free WiFi, bed sheets
Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.6 out of 10, (797)
"Staff and amenities "
United States
Keyshia
The price is Rp793.801
Rp971.610 total
includes taxes & fees
5 Jan - 6 Jan
Studio 6 San Antonio, TX - Medical Center
Free WiFi, bed sheets
Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1001)
"Great experience "
United States
John
The price is Rp713.070
Rp842.913 total
includes taxes & fees
5 Jan - 6 Jan
Motel 6 San Antonio, TX - Northwest Medical Center
Sauna
Hotel Gibbs Downtown Riverwalk

Hotel Gibbs Downtown Riverwalk

Hotel Gibbs Downtown Riverwalk
2.0 star property
Downtown San Antonio, 12.4 km from Medical Center District
9.0 out of 10, Wonderful, (1822)
"Great hotel in a great location "
United States
Breanna
The price is Rp1.607.785
Rp1.877.090 total
includes taxes & fees
5 Jan - 6 Jan
Hotel Gibbs Downtown Riverwalk
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
3.0 star property
Downtown San Antonio, 13 km from Medical Center District
7.8 out of 10, Good, (3798)
"Had an amazing time at the hotel "
United States
Uriel
The price is Rp1.185.948
Rp1.693.964 total
includes taxes & fees
5 Jan - 6 Jan
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Lobby
Menger Hotel

Menger Hotel

Menger Hotel
3.5 star property
Downtown San Antonio, 12.6 km from Medical Center District
9.0 out of 10, Wonderful, (3645)
"Beautiful hotel and location awesome "
United States
Leticia
The price is Rp1.668.000
Rp1.971.726 total
includes taxes & fees
7 Jan - 8 Jan
Menger Hotel
Indoor pool, outdoor pool
The Westin San Antonio North

The Westin San Antonio North

The Westin San Antonio North
4.0 star property
3.4 km from Medical Center District
8.6 out of 10, Excellent, (1233)
"Love this hotel!"
United States
Nora
The price is Rp1.386.123
Rp1.663.343 total
includes taxes & fees
9 Jan - 10 Jan
The Westin San Antonio North
Games room
Riverwalk Plaza

Riverwalk Plaza

Riverwalk Plaza
4.0 star property
12.3 km from Medical Center District
8.2 out of 10, Very good, (6262)
"Staff was great location was good price was excellent bar and restaurant was good price "
United States
David William
Riverwalk Plaza
Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers
Crockett Hotel

Crockett Hotel

Crockett Hotel
3.0 star property
Downtown San Antonio, 12.7 km from Medical Center District
8.8 out of 10, Excellent, (2527)
"Friendly staff, great location, good prices. "
United States
Gregorio
The price is Rp1.488.690
Rp1.759.766 total
includes taxes & fees
7 Jan - 8 Jan
Crockett Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.
Downtown - Riverwalk showing a river or creek, a bridge and boating

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

If you're spending some time in Uptown, San Antonio River and Marion Koogler McNay Art Museum are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Near East Side

If you're spending some time in Near East Side, Alamodome and Carver Community Cultural Center are top sights worth seeing.

Top Medical Center District Hotel Reviews

The Westin Riverwalk, San Antonio

The Westin Riverwalk, San Antonio

10/10 Excellent
"Very nice and clean rooms"
GUILLERMO 1-night trip
Posted 3 days ago
The Westin Riverwalk, San Antonio

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and The San Antonio Art Institute while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favourite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 123 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, The San Antonio Art Institute and Cinemark San Antonio 16 are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.