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Check prices for these dates

Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

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Our top choices for Medical Center District hotels

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

1. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,489 reviews)
"Breakfast was delicious, everything very clean and organized. Pool area was great easy check in and check out."
United States
Alba
The price is Rp1.610.731
Rp1.918.139 total
includes taxes & fees
26 Oct - 27 Oct
Drury Inn & Suites San Antonio Northwest Medical Center
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

2. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,713 reviews)
"Great place to stay"
United States
Gilbert
The price is Rp1.589.431
Rp1.892.773 total
includes taxes & fees
15 Oct - 16 Oct
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
A spacious lobby with a central staircase, seating area, and large windows.

3. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,170 reviews)
"The property was beautiful the staff was incredible"
United States
Adreanne
The price is Rp1.797.552
Rp2.151.890 total
includes taxes & fees
16 Oct - 17 Oct
San Antonio Marriott Northwest Medical Center
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

4. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,094 reviews)
"Hotel is clean and the staff is friendly"
United States
Tiffany
The price is Rp1.547.906
Rp1.807.180 total
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites by Marriott San Antonio Medical Center
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

5. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,002 reviews)
"Great property, nice rooms"
United States
Francisca
The price is Rp1.594.801
Rp1.899.169 total
includes taxes & fees
30 Oct - 31 Oct
Courtyard by Marriott Medical Center San Antonio
A modern kitchen with a large window, wooden counter, and two bar stools.

6. Park Inn by Radisson, Medical Center

Park Inn by Radisson, Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (1,002 reviews)
"Went with my partner, away from the bustle but still close to everything. Great little place."
United States
Jaime
The price is Rp1.201.918
Rp1.403.239 total
includes taxes & fees
31 Oct - 1 Nov
Park Inn by Radisson, Medical Center
A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.

7. Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (386 reviews)
"It's a good place to stay I"
United States
Ruben
The price is Rp856.288
Rp999.715 total
includes taxes & fees
14 Oct - 15 Oct
Studio 6 San Antonio, Tx - Northwest Medical Center
A modern bedroom with a large bed, bedside tables, a desk, and a chair.

8. Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (999 reviews)
"Staff was very helpful. Room was ok."
United States
Brian
The price is Rp788.093
Rp1.010.041 total
includes taxes & fees
11 Oct - 12 Oct
Motel 6 San Antonio, TX - Northwest Medical Center
A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.

9. Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (318 reviews)
"It’s. Nice place to stay, it’s big and comfortable."
United States
Jose Rolando
The price is Rp1.088.796
Rp1.271.169 total
includes taxes & fees
10 Nov - 11 Nov
Atria Inn & Suites
A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.

10. OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (248 reviews)
"great place to stay close to the hospital. Would stay there again"
United States
Melanie
The price is Rp1.158.960
Rp1.468.982 total
includes taxes & fees
10 Nov - 11 Nov
OYO Inn & Suites Medical Center San Antonio
A hotel room with a large bed, a desk with a chair, a television on a stand, and a mirror on the wall.

11. Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.2 out of 10, (575 reviews)
"Yes I would stay again"
United States
Jasper
The price is Rp787.556
Rp937.861 total
includes taxes & fees
11 Oct - 12 Oct
Flex Studios
A hotel room with two beds, a TV, a desk, and a kitchenette in the background.

12. Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (998 reviews)
"Good for a short stay traveling through the SA area."
United States
Jerron
Studio 6 Extended Stay - San Antonio, TX - Medical Center
A modern bar area with a central island, bar stools, and a kitchen counter with appliances.

13. Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center
3.0 star property
3.7 km from Medical Center District
8.4 out of 10, Very good, (1,071 reviews)
"Clean room, good Staff and delicious breakfast."
United States
Alejandra
The price is Rp1.666.095
Rp2.005.926 total
includes taxes & fees
18 Oct - 19 Oct
Hyatt Place San Antonio-Northwest/Medical Center
A conference room with rows of chairs, a large screen, and a carpeted floor.

14. Embassy Suites by Hilton San Antonio Landmark

Embassy Suites by Hilton San Antonio Landmark
3.5 star property
La Cantera District, 9.2 km from Medical Center District
9.6 out of 10, Exceptional, (1,004 reviews)
"Very nice employees, great welcoming, great breakfast"
United States
Lenita
The price is Rp3.418.709
Rp4.071.169 total
includes taxes & fees
25 Oct - 26 Oct
Embassy Suites by Hilton San Antonio Landmark
A modern building with a distinctive roof structure and a large illuminated sign.

15. Aloft by Marriott San Antonio UTSA Area

Aloft by Marriott San Antonio UTSA Area
3.0 star property
Northwest Side, 7.8 km from Medical Center District
9.0 out of 10, Wonderful, (1,001 reviews)
"Good stay"
United States
Juan
The price is Rp1.950.991
Rp2.323.338 total
includes taxes & fees
11 Oct - 12 Oct
Aloft by Marriott San Antonio UTSA Area
An indoor swimming pool with a hot tub, tiled flooring, and a seating area with tables and chairs.

16. Drury Inn & Suites Near La Cantera Parkway

Drury Inn & Suites Near La Cantera Parkway
3.0 star property
La Cantera District, 9.5 km from Medical Center District
9.4 out of 10, Exceptional, (2,000 reviews)
"Great stay!"
United States
Eduardo
The price is Rp1.682.327
Rp2.003.399 total
includes taxes & fees
25 Oct - 26 Oct
Drury Inn & Suites Near La Cantera Parkway
A modern kitchen with a central island, built-in appliances, and a coffee station.

17. Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport
3.0 star property
Uptown Central, 9.2 km from Medical Center District
8.6 out of 10, Excellent, (1,987 reviews)
"Location is good and close to airport"
United States
SWAROOP JADHAV
The price is Rp1.539.493
Rp1.833.395 total
includes taxes & fees
25 Oct - 26 Oct
Wyndham Garden San Antonio Airport
A hotel room with a bed, a sofa, a desk, and a chair.

18. Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG
2.5 star property
Northwest Side, 4.3 km from Medical Center District
8.0 out of 10, Very good, (1,255 reviews)
"Breakfast are good and staff very friendly."
United States
Johanna
The price is Rp1.378.223
Rp1.641.258 total
includes taxes & fees
9 Nov - 10 Nov
Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG
A modern hotel with a prominent sign reading "LA QUINTA".

19. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
9 km from Medical Center District
9.2 out of 10, Wonderful, (1,171 reviews)
"Very Cousy place for family’s, Having restaurants in walking distance a plus,plus."
United States
john
The price is Rp1.756.071
Rp2.050.213 total
includes taxes & fees
19 Oct - 20 Oct
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
A hotel with a modern design, featuring a covered parking area and multiple parking spaces.

20. Best Western Medical Center North Inn & Suites Near Six Flags

Best Western Medical Center North Inn & Suites Near Six Flags
2.5 star property
Northwest Side, 5.2 km from Medical Center District
8.2 out of 10, Very good, (1,605 reviews)
"Great front desk and overall great stay. Would stay here again."
United States
Jesus
The price is Rp1.190.462
Rp1.389.865 total
includes taxes & fees
15 Oct - 16 Oct
Best Western Medical Center North Inn & Suites Near Six Flags
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,094 reviews
View
A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,489 reviews
View
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,002 reviews
View
A spacious lobby with a central staircase, seating area, and large windows.
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,170 reviews
View
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,713 reviews
View

Hotels recommended for families in Medical Center District

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,489)
The price is Rp1.610.731
Rp1.918.139 total
includes taxes & fees
26 Oct - 27 Oct
Drury Inn & Suites San Antonio Northwest Medical Center

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.
A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

A riverside walkway with colorful umbrellas, a stone bridge, and historic buildings.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

A riverside walkway adorned with colorful umbrellas and festive lights.

Uptown Central

If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

A historic stone building with a large wooden door, arched windows, and ornate columns.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

Top Medical Center District Hotel Reviews

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

10/10 Excellent
"The Breakfast was great and hot every morning."
Marquise T 3-night trip
Posted 3 hours ago
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Consider a visit to Cinemark San Antonio 16 as part of your Medical Center District travel plans.
What's a favourite hotel to stay in Medical Center District?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include Drury Inn & Suites San Antonio Northwest Medical Center and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 124 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
Cinemark San Antonio 16 is an attraction you might want to check out while you're in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.