The Best Hotels Closest to Lewis and Clark Trail Trailhead in St. Louis - 2026 Updated Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Lewis and Clark Trail Trailhead hotels

A hotel room with a bed, a sofa, a coffee table, and wall art.

An indoor swimming pool with a clear view of the outside, a metal ladder, and a ceiling with recessed lighting.

A hotel lobby with a reception desk, seating area, and a large potted plant.

A Sleep Inn & Suites hotel with a modern brick facade, a covered entrance, and a parking lot.

1. Sleep Inn & Suites O'Fallon MO - Technology Drive

3.2 km from Lewis and Clark Trail Trailhead

Marie Ann

Rp1.452.027

Rp1.712.667 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

A hotel lobby with a seating area, a reception desk, and a flat-screen TV mounted on the wall.

A modern hotel room with a desk, chair, and a large mirror.

A reception desk with a modern design, featuring a blue geometric wall and a wooden finish.

2. Holiday Inn Express St. Louis West - O'Fallon by IHG

3.2 km from Lewis and Clark Trail Trailhead

murray

Rp1.778.711

Rp2.097.998 total

includes taxes & fees

27 Sept - 28 Sept

A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.

A spacious living area with a staircase, a large painting, and a chandelier.

A modern bathroom with a large mirror, white vanity, and a bathtub.

A hotel room with a large bed, a bedside lamp, a telephone, a mirror, and a bathroom with a sink and towel rack.

3. The Wildwood Hotel

14.7 km from Lewis and Clark Trail Trailhead

Hailey

Rp1.456.537

Rp1.696.690 total

includes taxes & fees

12 Oct - 13 Oct

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

A modern hotel entrance with a glass canopy, large windows, and a brick facade.

A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.

4. Hyatt Place St. Louis/Chesterfield

14.9 km from Lewis and Clark Trail Trailhead

Jolisa

Rp2.203.136

Rp2.555.372 total

includes taxes & fees

20 Sept - 21 Sept

A spacious lobby with a central round table, two sofas, and a chandelier.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.

A Drury Plaza hotel with a modern design, featuring a curved facade, large windows, and a Drury Plaza sign on the top.

5. Drury Plaza Hotel St. Louis Chesterfield

14.8 km from Lewis and Clark Trail Trailhead

Cassandra

Rp2.289.254

Rp2.655.260 total

includes taxes & fees

20 Sept - 21 Sept

A spacious lobby with a high ceiling, a dining area, and a seating area with sofas and a coffee table.

An outdoor patio area with a table and chairs, a glass door entrance, and a visible interior with a dining area.

A spacious lobby with a blue sofa, round coffee table, and blue chairs. There is a reception desk and a seating area with a high ceiling and large windows.

An indoor swimming pool with clear blue water, a tiled floor, and a ceiling with square vents.

6. Drury Inn & Suites St. Louis St. Peters

15 km from Lewis and Clark Trail Trailhead

Melanie

Rp1.937.034

Rp2.226.621 total

includes taxes & fees

20 Sept - 21 Sept

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A modern lobby with a reception desk, seating area, and a dining section.

A hotel room with two beds, a desk, a blue sofa, and a TV.

7. Holiday Inn Express & Suites St Peters by IHG

13.4 km from Lewis and Clark Trail Trailhead

Serah

Rp2.078.098

Rp2.497.610 total

includes taxes & fees

27 Sept - 28 Sept

A spacious lobby with a high ceiling, a central seating area with sofas and a coffee table, and a large window providing natural light.

A spacious lobby with a fireplace, comfortable seating, a large painting, and a view of the kitchen area.

A spacious lobby with a sofa, a coffee station, and a reception desk.

A shop with a variety of snacks and beverages, including a refrigerated section with drinks and a display of packaged snacks.

8. Hilton Garden Inn St. Louis/O'Fallon MO

7.1 km from Lewis and Clark Trail Trailhead

Kassie

Rp1.906.215

Rp2.260.296 total

includes taxes & fees

4 Oct - 5 Oct

A multi-story hotel with a central entrance featuring a covered patio area.

A hotel room with a desk, chair, sofa, and a window with curtains.

A hotel with a swimming pool, outdoor seating, and a covered patio area.

A hotel lobby with a sectional sofa, a fireplace, a flat-screen TV, and framed artwork on the walls.

9. Staybridge Suites O'Fallon Chesterfield by IHG

3.2 km from Lewis and Clark Trail Trailhead

Norman

Rp1.954.821

Rp2.305.713 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio area with wicker furniture and a central fire feature.

A Courtyard Marriott hotel with a parking lot and a green shuttle service.

A modern hotel lobby with a reception desk, seating area, and a television screen displaying a map.

A hotel room with a bed, a sofa, a desk, and a chair.

10. Courtyard by Marriott St. Louis Chesterfield

10.9 km from Lewis and Clark Trail Trailhead

Kelly

Rp2.123.887

Rp2.471.418 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio area with a stone fire pit, wicker furniture, and a covered seating area with a view of the building's interior.

A hotel room with a sofa, a side table, a lamp, a flat-screen TV, and a bed with a red blanket.

A multi-story hotel with a brick facade, a covered outdoor seating area with a fire feature, and a sign indicating it is a Marriott property.

A hotel room with a large bed, bedside lamps, a TV, a desk, and a bathroom.

11. TownePlace Suites by Marriott St. Louis Chesterfield

5.8 km from Lewis and Clark Trail Trailhead

Bobbi jo

Rp2.254.208

Rp2.645.606 total

includes taxes & fees

5 Oct - 6 Oct

An outdoor patio with a built-in grill, seating area, and stone walls.

A modern lobby with a stone accent wall, a flat-screen TV, a reception desk, seating area with sofas and ottomans, and a patterned rug.

A multi-story hotel with a parking lot in front.

An indoor swimming pool with clear glass walls, sunlit seating area, and lifeguard station.

12. Residence Inn by Marriott St. Louis Chesterfield

12.4 km from Lewis and Clark Trail Trailhead

Brandon

Rp3.328.479

Rp3.893.922 total

includes taxes & fees

20 Sept - 21 Sept

A hotel room with two beds, a desk, a chair, a TV, and a large window.

A modern dining area with a brick fireplace, yellow and blue chairs, and a blue sofa.

A spacious lobby with a blue sofa set, a reception desk, and a modern chandelier.

A modern hotel room with a sofa, a small table, a yellow ottoman, a wooden desk, a flat-screen TV, and a bathtub.

13. Comfort Inn & Suites Chesterfield - St. Louis

6.6 km from Lewis and Clark Trail Trailhead

Jessica

Rp1.414.692

Rp1.707.818 total

includes taxes & fees

20 Sept - 21 Sept

A courtyard with a central seating area, surrounded by trees and a building with a pitched roof.

A reception desk with a "WELCOME TO THE SHOW ME STATE" sign, a wooden counter, and a Hilton Honors sign.

A store interior with a 'Treats' sign, snack shelves, and a chalkboard with a welcome message.

A modern hotel room with a large window, a desk with a flat-screen TV, a comfortable seating area, and a decorative wall piece.

14. Hampton Inn & Suites St. Louis/Chesterfield

10.9 km from Lewis and Clark Trail Trailhead

Vijay

Rp1.935.097

Rp2.251.738 total

includes taxes & fees

27 Sept - 28 Sept

A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows allowing natural light.

A Hampton Inn with a brick facade, outdoor seating area, and a clear sky.

A modern hotel room with a neatly made bed, a bedside table with a lamp, a wall-mounted artwork, and a small seating area with a bench.

An indoor swimming pool with a clear water area, a shallow end, and a tiled deck surrounding the pool. There are lounge chairs and tables on the deck, and a sign indicating a maximum capacity of 62.

15. Hampton Inn St. Louis Wentzville

17.1 km from Lewis and Clark Trail Trailhead

Jill

Rp2.296.122

Rp2.627.911 total

includes taxes & fees

28 Sept - 29 Sept

A multi-story hotel with a stone facade and a covered entrance.

A modern living room with a blue accent wall, a gray sofa, a dining table with chairs, and a coffee table.

A compact hotel room with two beds, a desk with a chair, a television, a microwave, and a refrigerator.

A modern living room with a wooden dining table, grey chairs, a sofa, and a coffee machine.

16. WoodSpring Suites St Peters-OFallon

13.6 km from Lewis and Clark Trail Trailhead

Ellen

Rp1.436.177

Rp1.700.518 total

includes taxes & fees

16 Sept - 17 Sept

A modern kitchen area with a breakfast bar, a coffee machine, and a refrigerator displaying menu options.

A Holiday Inn Express & Suites building with a brick facade, a covered entrance, and a numbered address.

A coffee station with two coffee machines and a display of coffee pods and cups.

A hotel room with two beds, a blue sofa, a small table, and a kitchenette.

17. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

10.3 km from Lewis and Clark Trail Trailhead

NEBAHAT

Rp1.937.210

Rp2.254.196 total

includes taxes & fees

20 Sept - 21 Sept

A hotel reception area with a counter, coffee machines, a refrigerated display, and artwork on the wall.

An indoor swimming pool with clear water, a diving board, and a seating area with tables and chairs.

A reception desk with a wooden finish, a clock, and a sign for Marriott Bonvoy.

A snack bar with shelves of chips, candies, and bottled water.

18. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

15.6 km from Lewis and Clark Trail Trailhead

Thomas Kent

Rp1.886.138

Rp2.187.693 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor seating area with a table and chairs, a fire feature, and a brick wall.

A hotel room with a bed, bedside tables, a wardrobe, and a window with curtains.

A hotel lobby with a seating area, tables, and a TV screen.

A modern hotel with a flat roof, large windows, and a prominent signage for 'SPRINGHILL SUITES.'

19. SpringHill Suites by Marriott St. Louis Chesterfield

15.6 km from Lewis and Clark Trail Trailhead

Omar

Rp2.148.542

Rp2.492.051 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio area with wicker furniture, a stone fire pit, and a building in the background.

A modern lobby with a sofa, armchairs, a coffee table, and a bookshelf.

A modern bar area with wooden furniture, a counter with a menu, and a seating area with tables and chairs.

20. Courtyard by Marriott St. Louis St. Peters

17.3 km from Lewis and Clark Trail Trailhead

Krischel

Rp2.123.887

Rp2.550.703 total

includes taxes & fees

20 Sept - 21 Sept

View all properties

Compare popular hotels close to Lewis and Clark Trail Trailhead

Property	Property class	Guest rating
Sleep Inn & Suites O'Fallon MO - Technology Drive	9.0 1127 1,127 reviews	View
Holiday Inn Express St. Louis West - O'Fallon by IHG	8.6 989 989 reviews	View
The Wildwood Hotel	9.2 1673 1,673 reviews	View
Hyatt Place St. Louis/Chesterfield	9.6 1002 1,002 reviews	View
Drury Plaza Hotel St. Louis Chesterfield	9.6 1268 1,268 reviews	View

Top Lewis and Clark Trail Trailhead Hotel Reviews

Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent

"Super clean rooms, pool area was nice, delicious afternoon cookies, great coffee, beautiful location!"

Sleep Inn & Suites O'Fallon MO - Technology Drive

10/10 Excellent

"Well maintained and friendly staff"

Drury Plaza Hotel St. Louis Creve Coeur

10/10 Excellent

"Drury is always a safe bet!"

Ameristar Casino Resort and Spa

10/10 Excellent

"Everything was as promised and can’t wait to go back. Worth the drive and everything"

Drury Inn & Suites St. Louis St. Peters

10/10 Excellent

"Staff was great!!!"

Hollywood Casino & Hotel St. Louis

10/10 Excellent

"Clean Bed was sooo comfy"

Pear Tree Inn St. Louis Airport

8/10 Good

"The young lady at the front desk was very friendly and welcoming, which I appreciate. The breakfast was quite tasty. My only inconvenience was the air conditioner, because it was loud and it was difficult to stay asleep when it did turn on. I have stayed at the Drury Inn before many years ago so I thought I would try Pear Inn, which didn’t disappoint."

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

10/10 Excellent

"Staff was welcoming and polite."

Comfort Suites St Charles - St Louis

8/10 Good

"Based on pictures from their website, we expected some hot food at breakfast. Something like biscuits and gravy or scrambled eggs and sausage. There were only basic continental options with waffles and oatmeal being the only thing hot."

Other attractions near Lewis and Clark Trail Trailhead

A wooden dock extending into a pond with lily pads, surrounded by lush greenery and a clear blue sky.

August A. Busch Memorial Conservation Area

8.6/10 (7 reviews)

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savour the top-notch restaurants.

See properties

A chain-link fence with a red sign that reads "REMEMBRANCE DAY" and a date "09-11-01".

9-11 Memorial

7.6/10 (44 reviews)

Learn about the local history of O'Fallon when you spend time at 9-11 Memorial. While in this family-friendly area, you can savour the top-notch restaurants.

See properties

Weldon Spring Site Interpretive Center

8.2/10 (14 reviews)

You can spend time studying the exhibits at Weldon Spring Site Interpretive Center during your trip to Weldon Spring Heights. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants.

See properties

Hamburg Trail Trailhead

You can take time to visit Hamburg Trail Trailhead during your travels to Hamburg.

See properties

Missouri Bluffs Golf Course

7.6/10 (40 reviews)

Enjoy a round of golf in Weldon Spring Heights at Missouri Bluffs Golf Course. Experience the great live music or attend a sporting event in this family-friendly area.

See properties

St. Louis Premium Outlets

8.8/10 (369 reviews)

You can find the perfect gifts to bring home at St. Louis Premium Outlets during your stay in Chesterfield. Discover the top-notch restaurants and great live music in this family-friendly area.

See properties

Golf Headquarters Family Golfplex

You can take time to visit Golf Headquarters Family Golfplex during your travels to O'Fallon. Visit the shops in this family-friendly area or simply enjoy its restaurants.

See properties

Babler State Park

8.6/10 (59 reviews)

You can take time to visit Babler State Park during your travels to Chesterfield. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants.

See properties

Frequently asked questions

What's the area like around Lewis and Clark Trail Trailhead?

Lewis and Clark Trail Trailhead is located in Weldon Spring Heights. You'll find 27 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to Lewis and Clark Trail Trailhead?

Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located 2 mi (3.2 km) from Lewis and Clark Trail Trailhead. Other good options around the area include Holiday Inn Express & Suites St. Louis - Chesterfield by IHG and The Wildwood Hotel.

How many hotels can I expect to find near Lewis and Clark Trail Trailhead?

Expedia has 27 hotels and other accommodation options a few miles from Lewis and Clark Trail Trailhead.

If I need to cancel the hotel reservation for my stay near Lewis and Clark Trail Trailhead, will I receive a refund?

Yes, most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the best options available near Lewis and Clark Trail Trailhead.

What can I see and do near Lewis and Clark Trail Trailhead?

Explore nature at August A. Busch Memorial Conservation Area and Hamburg Trail Trailhead. Missouri Bluffs Golf Course, Babler State Park and Golf Headquarters Family Golfplex are worth a stop while you're in the area. St. Louis Premium Outlets and 9-11 Memorial are both worth a visit while you're out exploring.

Search Hotels Near Lewis and Clark Trail Trailhead, St. Louis

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lewis and Clark Trail Trailhead hotels

1. Sleep Inn & Suites O'Fallon MO - Technology Drive

2. Holiday Inn Express St. Louis West - O'Fallon by IHG

3. The Wildwood Hotel

4. Hyatt Place St. Louis/Chesterfield

5. Drury Plaza Hotel St. Louis Chesterfield

6. Drury Inn & Suites St. Louis St. Peters

7. Holiday Inn Express & Suites St Peters by IHG

8. Hilton Garden Inn St. Louis/O'Fallon MO

9. Staybridge Suites O'Fallon Chesterfield by IHG

10. Courtyard by Marriott St. Louis Chesterfield

11. TownePlace Suites by Marriott St. Louis Chesterfield

12. Residence Inn by Marriott St. Louis Chesterfield

13. Comfort Inn & Suites Chesterfield - St. Louis

14. Hampton Inn & Suites St. Louis/Chesterfield

15. Hampton Inn St. Louis Wentzville

16. WoodSpring Suites St Peters-OFallon

17. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

18. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

19. SpringHill Suites by Marriott St. Louis Chesterfield

20. Courtyard by Marriott St. Louis St. Peters

Compare popular hotels close to Lewis and Clark Trail Trailhead

Top Lewis and Clark Trail Trailhead Hotel Reviews

Country Inn & Suites by Radisson, St. Charles Historic District

Sleep Inn & Suites O'Fallon MO - Technology Drive

Drury Plaza Hotel St. Louis Creve Coeur

Ameristar Casino Resort and Spa

Drury Inn & Suites St. Louis St. Peters

Hollywood Casino & Hotel St. Louis

Pear Tree Inn St. Louis Airport

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Comfort Suites St Charles - St Louis

Other attractions near Lewis and Clark Trail Trailhead

August A. Busch Memorial Conservation Area

9-11 Memorial

Weldon Spring Site Interpretive Center

Hamburg Trail Trailhead

Missouri Bluffs Golf Course

St. Louis Premium Outlets

Golf Headquarters Family Golfplex

Babler State Park

Frequently asked questions