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12 Dec - 13 Dec
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13 Dec - 14 Dec
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12 Dec - 14 Dec
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19 Dec - 21 Dec

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Our top choices for Lewis and Clark Trail Trailhead hotels

Premium bedding, desk, iron/ironing board, free WiFi
Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
3.2 km from Lewis and Clark Trail Trailhead
8.8 out of 10, Excellent, (1001)
"Nice breakfast, friendly staff"
United States
Damon
The price is Rp1.395.781
Rp1.646.324 total
includes taxes & fees
15 Dec - 16 Dec
Sleep Inn & Suites O'Fallon MO - Technology Drive
Exterior
Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
3.2 km from Lewis and Clark Trail Trailhead
8.6 out of 10, Excellent, (833)
"The staff was so friendly and helpful! The hotel was exceptionally clean. Breakfast was very good with lots of variety!"
United States
Millie
The price is Rp1.384.108
Rp1.632.554 total
includes taxes & fees
15 Dec - 16 Dec
Holiday Inn Express St. Louis West - O'Fallon by IHG
Lobby
Residence Inn by Marriott O'Fallon

Residence Inn by Marriott O'Fallon

Residence Inn by Marriott O'Fallon
3.0 star property
3.6 km from Lewis and Clark Trail Trailhead
8.4 out of 10, Very good, (453)
"Love the stay great for families!"
United States
jeriece
The price is Rp1.750.980
Rp2.065.280 total
includes taxes & fees
26 Dec - 27 Dec
Residence Inn by Marriott O'Fallon
Exterior
Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG
3.0 star property
3.2 km from Lewis and Clark Trail Trailhead
8.4 out of 10, Very good, (407)
"Nice sized suite, the folks were friendly, the breakfast was better than most. I will stay there again."
United States
Steven
The price is Rp1.934.416
Rp2.281.645 total
includes taxes & fees
29 Dec - 30 Dec
Staybridge Suites O'Fallon Chesterfield by IHG
Property amenity
TownePlace Suites by Marriott St. Louis Chesterfield

TownePlace Suites by Marriott St. Louis Chesterfield

TownePlace Suites by Marriott St. Louis Chesterfield
3.0 star property
5.6 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (267)
"Our group comes for the Christmas shopping. It's convenient and close to the Premium outlet stores and is a good base for the additional shopping we do. We stay at the hotel rather than go back and forth from home. Breakfast availability helps save time looking for places to go. Staff has always been friendly and helpful. "
United States
Floyd and Linda
The price is Rp1.984.444
Rp2.329.003 total
includes taxes & fees
14 Dec - 15 Dec
TownePlace Suites by Marriott St. Louis Chesterfield
Lobby sitting area
Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO
3.0 star property
7.1 km from Lewis and Clark Trail Trailhead
8.8 out of 10, Excellent, (717)
"Clean room, quiet"
United States
Laura
The price is Rp1.425.298
Rp1.690.048 total
includes taxes & fees
28 Dec - 29 Dec
Hilton Garden Inn St. Louis/O'Fallon MO
Standard Room, 2 Queen Beds, Non Smoking | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains
Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites Chesterfield - St. Louis
2.5 star property
6.6 km from Lewis and Clark Trail Trailhead
8.0 out of 10, Very good, (1003)
"Nice and quiet the location is great for softball fields"
United States
James
The price is Rp1.335.914
Rp1.612.875 total
includes taxes & fees
5 Jan - 6 Jan 2026
Comfort Inn & Suites Chesterfield - St. Louis
BBQ/picnic Area
Courtyard by Marriott St. Louis Chesterfield

Courtyard by Marriott St. Louis Chesterfield

Courtyard by Marriott St. Louis Chesterfield
3.0 star property
10.9 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (576)
"Very clean hotel with great staff "
United States
brad
The price is Rp1.784.332
Rp2.076.302 total
includes taxes & fees
19 Dec - 20 Dec
Courtyard by Marriott St. Louis Chesterfield
Free daily full breakfast
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
2.5 star property
10.3 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (1002)
"Great hotel!"
United States
Lorelei
The price is Rp1.717.628
Rp1.998.682 total
includes taxes & fees
22 Dec - 23 Dec
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
Exterior
WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
13.6 km from Lewis and Clark Trail Trailhead
9.8 out of 10, Exceptional, (17)
"The room was super clean and tidy. The staff was very friendly and overall a great experience. "
United States
Fred
The price is Rp1.234.024
Rp1.418.512 total
includes taxes & fees
15 Dec - 16 Dec
WoodSpring Suites St Peters-OFallon
Courtyard
Hampton Inn & Suites St. Louis/Chesterfield

Hampton Inn & Suites St. Louis/Chesterfield

Hampton Inn & Suites St. Louis/Chesterfield
3.5 star property
10.9 km from Lewis and Clark Trail Trailhead
8.8 out of 10, Excellent, (843)
"It was great, clean, quiet and friendly! "
United States
Lisa
The price is Rp1.654.259
Rp1.924.945 total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn & Suites St. Louis/Chesterfield
Room, Accessible | Desk, iron/ironing board, free WiFi, bed sheets
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
12.5 km from Lewis and Clark Trail Trailhead
6.8 out of 10, (995)
"Very run down and trash around the property, but the room was clean and comfortable for our one night stop. Convenience of the location"
United States
Natalie
The price is Rp1.063.095
Rp1.253.919 total
includes taxes & fees
22 Dec - 23 Dec
Super 8 by Wyndham O'Fallon MO/St. Louis Area
Property entrance
The Wildwood Hotel

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
14.7 km from Lewis and Clark Trail Trailhead
9.2 out of 10, Wonderful, (1607)
"Great place!"
United States
Biju
The price is Rp1.382.279
Rp1.675.394 total
includes taxes & fees
14 Dec - 15 Dec
The Wildwood Hotel
Property amenity
Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
3.0 star property
12.4 km from Lewis and Clark Trail Trailhead
9.6 out of 10, Exceptional, (199)
"Very clean and safe place, wonderful location "
United States
Ashley
The price is Rp3.151.764
Rp3.687.187 total
includes taxes & fees
19 Dec - 20 Dec
Residence Inn by Marriott St. Louis Chesterfield
Lobby
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
14.8 km from Lewis and Clark Trail Trailhead
9.6 out of 10, Exceptional, (1038)
"Great place to stay! "
United States
Stephanie
The price is Rp2.167.713
Rp2.514.241 total
includes taxes & fees
17 Dec - 18 Dec
Drury Plaza Hotel St. Louis Chesterfield
Bar (on property)
Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
3.0 star property
14.9 km from Lewis and Clark Trail Trailhead
9.6 out of 10, Exceptional, (1000)
"Great place to stay"
United States
David
The price is Rp2.055.317
Rp2.383.920 total
includes taxes & fees
14 Dec - 15 Dec
Hyatt Place St. Louis/Chesterfield
Lobby
Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
15 km from Lewis and Clark Trail Trailhead
9.4 out of 10, Exceptional, (1000)
"Great hotel! Clean, friendly staff, wonderful amenities!"
United States
Susan
The price is Rp1.834.193
Rp2.108.513 total
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites St. Louis St. Peters
Lobby
Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
13.7 km from Lewis and Clark Trail Trailhead
6.4 out of 10, (1000)
"Staff was very friendly. Room was kept clean."
United States
Sandra
The price is Rp1.063.095
Rp1.222.027 total
includes taxes & fees
11 Jan - 12 Jan 2026
Days Inn by Wyndham St Peters/St Charles
Exterior
Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
13.4 km from Lewis and Clark Trail Trailhead
9.2 out of 10, Wonderful, (371)
"Room was very clean and great amenities. Breakfast was decent. Great value"
United States
Marcus
The price is Rp1.684.276
Rp2.036.297 total
includes taxes & fees
17 Dec - 18 Dec
Holiday Inn Express & Suites St Peters by IHG
Cleanliness standards
Relax Inn Saint Charles

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
18.2 km from Lewis and Clark Trail Trailhead
6.6 out of 10, (1004)
"Great place to stay "
United States
Askar
The price is Rp1.050.588
Rp1.207.342 total
includes taxes & fees
14 Dec - 15 Dec
Relax Inn Saint Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Lewis and Clark Trail Trailhead Hotel Reviews

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

10/10 Excellent
"Clean room, easy check in"
lizbeth 1-night trip
Posted 6 days ago
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Hotels near other Lewis and Clark Trail Trailhead attractions

Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savour the top-notch restaurants.
See properties
9-11 memorial in New York

9-11 Memorial

3.9/5 (30 reviews)
Learn about the local history of O'Fallon when you spend time at 9-11 Memorial. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Lewis and Clark Trail Trailhead?
Lewis and Clark Trail Trailhead is located in Weldon Spring Heights. You'll find 28 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay close to Lewis and Clark Trail Trailhead?
The Wildwood Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. You'll find it 9.1 mi (14.7 km) from Lewis and Clark Trail Trailhead. Other good options around the area include Sonesta ES Suites St. Louis - Chesterfield and Drury Plaza Hotel St. Louis Chesterfield.
How many hotels can I expect to find near Lewis and Clark Trail Trailhead?
Expedia has 28 hotels and other accommodation options a few miles from Lewis and Clark Trail Trailhead.
If I need to cancel the hotel reservation for my stay near Lewis and Clark Trail Trailhead, will I receive a refund?
Yes, most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the best options available near Lewis and Clark Trail Trailhead.
What can I see and do near Lewis and Clark Trail Trailhead?
Explore nature at August A. Busch Memorial Conservation Area and Hamburg Trail Trailhead. Missouri Bluffs Golf Course, Golf Headquarters and Babler State Park are worth a stop while you're in the area. St. Louis Premium Outlets and 9-11 Memorial are both worth a visit while you're out exploring.