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3 Mar - 4 Mar
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Our top choices for Mayo Clinic Florida hotels

Lobby lounge

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (469 reviews)
"Clean room, amazing staff great location "
United States
Darlene
The price is Rp2.951.900
Rp3.350.407 total
includes taxes & fees
29 Mar - 30 Mar
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Breakfast, lunch, dinner served; American cuisine

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (162 reviews)
"Great place to stay"
United States
Judy
The price is Rp3.129.857
Rp3.552.388 total
includes taxes & fees
3 Apr - 4 Apr
Hilton Jacksonville At Mayo Clinic
Terrace/patio

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (585 reviews)
"Comfortable room, very nice staff. Great location."
United States
Andrew
The price is Rp2.064.801
Rp2.343.548 total
includes taxes & fees
22 Mar - 23 Mar
TownePlace Suites by Marriott Jacksonville East
Lobby

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Enjoyed the complimentary breakfast. "
United States
Andrew
The price is Rp1.922.615
Rp2.182.169 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Lobby sitting area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,007 reviews)
"Staff was nice and room was clean "
United States
Charles
The price is Rp2.041.028
Rp2.316.567 total
includes taxes & fees
3 Apr - 4 Apr
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Terrace/patio

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (765 reviews)
"Great location "
United States
Josiah Christine
The price is Rp3.307.039
Rp3.753.490 total
includes taxes & fees
3 Apr - 4 Apr
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Property amenity

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (539 reviews)
"Great place (and location)!"
United States
Dale
The price is Rp2.277.180
Rp2.584.599 total
includes taxes & fees
22 Mar - 23 Mar
Element Jacksonville Beach
Exterior

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,006 reviews)
"Great location, friendly staff, nice rooms, great breakfast."
United States
Michelle
The price is Rp2.209.708
Rp2.508.018 total
includes taxes & fees
30 Mar - 31 Mar
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Standard Room, 1 King Bed, Non Smoking | Down duvets, minibar, iron/ironing board, WiFi

The Hotel Palms

The Hotel Palms
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (294 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is Rp3.188.052
Rp3.618.523 total
includes taxes & fees
2 Apr - 3 Apr
The Hotel Palms
Exterior

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,033 reviews)
"Clean room, good breakfast and location"
United States
Jesus
The price is Rp2.188.689
Rp2.484.161 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Couples treatment room(s), sauna, hot tub, steam room, body treatments

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (815 reviews)
"Amazing. Loved it "
United States
Carol
The price is Rp10.947.332
Rp12.695.447 total
includes taxes & fees
4 Mar - 5 Mar
Ponte Vedra Inn & Club
Lobby

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,712 reviews)
"Yes room was spotless and staff was amazing!"
United States
Martina
The price is Rp2.704.386
Rp3.069.671 total
includes taxes & fees
9 Mar - 10 Mar
Margaritaville Jacksonville Beach
2 restaurants, breakfast served

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (688 reviews)
"Clean room, excellent service and only steps from the ocean. The facility could use some TLC but, all in all, a wonderful place to stay. We’ll be back for sure. "
United States
Robert
The price is Rp10.103.932
Rp11.755.056 total
includes taxes & fees
4 Mar - 5 Mar
The Lodge and Club at Ponte Vedra Beach
On the beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,013 reviews)
"Great location, breakfast was delicious "
United States
Paul
The price is Rp2.023.991
Rp2.297.253 total
includes taxes & fees
22 Mar - 23 Mar
Best Western Oceanfront
Lobby

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,005 reviews)
"Very friendly staff, good restaurants in hotel and in the complex "
United States
Richard
The price is Rp2.807.847
Rp3.130.750 total
includes taxes & fees
22 Mar - 23 Mar
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Outdoor pool, pool umbrellas, pool loungers

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,001 reviews)
"Beds very comfortable. Check-in seamless. I loved my stay."
United States
Pizza
The price is Rp3.273.465
Rp3.715.383 total
includes taxes & fees
22 Mar - 23 Mar
Four Points by Sheraton Jacksonville Beachfront
Sports facility

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,002 reviews)
"very friendly staff!! i love staying here!!"
United States
Evani
The price is Rp2.277.180
Rp2.584.599 total
includes taxes & fees
21 Mar - 22 Mar
Hyatt Place Jacksonville / St. Johns Town Center
Free daily buffet breakfast

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,005 reviews)
"Hotel was clean, breakfast was perfect."
United States
Kurt
The price is Rp2.199.097
Rp2.495.975 total
includes taxes & fees
16 Mar - 17 Mar
Holiday Inn Express Jacksonville Beach by IHG
Snack bar

Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
Southside, 8.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (868 reviews)
"Clean room, professional staff, & good breakfast bar"
United States
Dwight
The price is Rp2.001.894
Rp2.272.150 total
includes taxes & fees
29 Mar - 30 Mar
Tru By Hilton Jacksonville St Johns Town Center
2 outdoor pools, open 7:00 AM to 9:00 PM, pool umbrellas, pool loungers

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,652 reviews)
"Everyone was friendly, kind and went out of their way to help with anything we needed. Great staff, great stay!"
United States
Barbara
The price is Rp2.890.838
Rp3.281.101 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Jacksonville Beach/Oceanfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Clinic Florida Hotel Reviews

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG

8/10 Good
"Was a good experience. The walls are seem to be thin as we could hear a lot of noise outside. Do wish the tv had more channel options i.e. netflix etc "
Monroe 2-night trip
Posted 2 hours ago
Holiday Inn Express Jacksonville Beach by IHG

Hotels near other Mayo Clinic Florida attractions

Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event.
See properties

Windsor Commons Shopping Center

You can find the perfect gifts to bring home at Windsor Commons Shopping Center during your trip to Jacksonville. Experience the area's great live music and entertainment choices.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 47 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 47 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, Players by the Sea and SeaWalk Pavillion. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.