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Our top choices for Mayo Clinic Florida hotels

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (246 reviews)
"Beautiful hotel!! It was extremely quiet and we all slept amazing!!"
United States
christine
The price is Rp3.226.622
Rp3.662.216 total
includes taxes & fees
16 Jun - 17 Jun
Hilton Jacksonville At Mayo Clinic

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (528 reviews)
"Great place to stay!"
United States
Chad
The price is Rp2.902.215
Rp3.294.014 total
includes taxes & fees
19 Jun - 20 Jun
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (622 reviews)
"This is always a great place to stay especially because it’s close to the Mayo Clinic …a five minute drive"
United States
Miriam
The price is Rp2.011.965
Rp2.283.581 total
includes taxes & fees
14 Jun - 15 Jun
TownePlace Suites by Marriott Jacksonville East

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,010 reviews)
"Convenient location; clean and comfortable room; very friendly and helpful front desk staff"
United States
Tonya
The price is Rp2.190.015
Rp2.485.668 total
includes taxes & fees
21 Jun - 22 Jun
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,003 reviews)
"Location: many business and restaurants to choose from and beach just down the road: staff very professional and knowledgeable and friendly and accommodating"
United States
Debra
The price is Rp1.944.306
Rp2.206.787 total
includes taxes & fees
21 Jun - 22 Jun
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (776 reviews)
"Enjoyed our stay"
United States
Alan
The price is Rp2.706.360
Rp3.071.719 total
includes taxes & fees
13 Jun - 14 Jun
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

The Hotel Palms Poolside

The Hotel Palms Poolside
2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (479 reviews)
"Very clean and quiet, even with the festival in AB. Felt very safe. Loved the pool area!"
United States
Liza
The price is Rp3.215.476
Rp3.649.564 total
includes taxes & fees
29 Jun - 30 Jun
The Hotel Palms Poolside

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
Deerwood, 7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (61 reviews)
"Great location and awesome staff"
United States
Beth
The price is Rp2.255.003
Rp2.559.428 total
includes taxes & fees
11 Jun - 12 Jun
Hyatt Studios Jacksonville/St Johns Town Center

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,005 reviews)
"Great place to stay"
United States
Clyde
The price is Rp2.279.040
Rp2.586.711 total
includes taxes & fees
29 Jun - 30 Jun
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

The Hotel Palms Courtyard

The Hotel Palms Courtyard
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (302 reviews)
"Clean, room was very nice, staff was helpful"
United States
Angela
The price is Rp3.384.695
Rp3.841.629 total
includes taxes & fees
4 Jun - 5 Jun
The Hotel Palms Courtyard

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,129 reviews)
"Great location not too far from beaches restsurants, and shopping."
United States
Donna L.
The price is Rp2.652.945
Rp3.011.182 total
includes taxes & fees
7 Jun - 8 Jun
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (822 reviews)
"Beautiful room looking at the ocean, staff super helpful, property immaculate."
United Kingdom
Michael
The price is Rp8.884.695
Rp10.422.780 total
includes taxes & fees
14 Jun - 15 Jun
Ponte Vedra Inn & Club

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (695 reviews)
"Very nice resort! Staff is friendly, clean and great restaurants outside."
United States
Raymond
The price is Rp7.994.445
Rp9.430.151 total
includes taxes & fees
7 Jun - 8 Jun
The Lodge and Club at Ponte Vedra Beach

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (4,015 reviews)
"Very nice staff and beautiful property"
United States
Marley
The price is Rp2.976.996
Rp3.378.890 total
includes taxes & fees
7 Jun - 8 Jun
Margaritaville Jacksonville Beach

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
10.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (105 reviews)
"Great staff and breakfast!"
United States
Kandi
The price is Rp2.546.115
Rp2.889.841 total
includes taxes & fees
21 Jun - 22 Jun
TownePlace Suites by Marriott® Jacksonville Mayport

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (203 reviews)
"Great stay! Highly recommend and tons to do in the area."
United States
Adam
The price is Rp3.187.095
Rp3.617.354 total
includes taxes & fees
4 Jun - 5 Jun
AC Hotel Jacksonville St Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,041 reviews)
"Great stay!"
United States
William
The price is Rp2.264.796
Rp2.570.508 total
includes taxes & fees
4 Jun - 5 Jun
Hyatt Place Jacksonville / St. Johns Town Center

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location, very nice staff"
United States
Maria
The price is Rp2.663.450
Rp3.023.015 total
includes taxes & fees
14 Jun - 15 Jun
Best Western Oceanfront

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,006 reviews)
"The hotel and the staff were amazing! My family had a wonderful time there, the rooms were clean and a good breakfast! Excellent location!"
United States
Maria
The price is Rp2.225.625
Rp2.526.085 total
includes taxes & fees
14 Jun - 15 Jun
Holiday Inn Express Jacksonville Beach by IHG

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Very nice property and staff"
United States
BONINA
The price is Rp3.917.100
Rp4.445.909 total
includes taxes & fees
16 Jun - 17 Jun
Four Points by Sheraton Jacksonville Beachfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Breakfast, lunch and dinner served
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.4
Exceptional
246 reviews
View
Lobby lounge
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
528 reviews
View
Terrace/patio
TownePlace Suites by Marriott Jacksonville East
3.0 star property
9.2
Wonderful
622 reviews
View
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
9.0
Wonderful
1,010 reviews
View
Lobby
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,003 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 45 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 45 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, Wilson Center For the Arts and Players by the Sea. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Gonzales Park. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.