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10 Dec - 11 Dec
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Our top choices for Museum of Life and Science hotels

Lobby
Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85
2.5 star property
1.4 km from Museum of Life and Science
9.0 out of 10, Wonderful, (1005)
"Nice place to stay and close to everything. "
United States
Christy
The price is Rp1.720.963
Rp1.953.294 total
includes taxes & fees
23 Dec - 24 Dec
Hampton Inn & Suites Durham/North I-85
Free buffet breakfast
Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG
2.5 star property
2.2 km from Museum of Life and Science
8.8 out of 10, Excellent, (949)
"Room was great"
United States
Barbara
The price is Rp1.634.248
Rp1.855.038 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express Durham by IHG
Premium bedding, desk, blackout curtains, iron/ironing board
Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University
2.5 star property
Croasdaile Farm Master, 3.2 km from Museum of Life and Science
8.6 out of 10, Excellent, (1000)
"Loved our stay"
United States
Brian
The price is Rp1.581.218
Rp1.794.683 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn & Suites Durham near Duke University
Lobby
Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center
2.0 star property
2.2 km from Museum of Life and Science
6.8 out of 10, (1000)
"Good motel...clean, easy acess "
United States
Howard
The price is Rp967.891
Rp1.126.946 total
includes taxes & fees
21 Dec - 22 Dec
Red Roof Inn Durham - Duke Univ Medical Center
Miscellaneous
Super 8 by Wyndham Durham/University Area NC

Super 8 by Wyndham Durham/University Area NC

Super 8 by Wyndham Durham/University Area NC
2.0 star property
2.1 km from Museum of Life and Science
5.0 out of 10, (344)
"The environment was not pleasant "
United States
Denise
The price is Rp1.063.095
Rp1.206.612 total
includes taxes & fees
26 Dec - 27 Dec
Super 8 by Wyndham Durham/University Area NC
Reception
Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center
2.5 star property
4.8 km from Museum of Life and Science
9.6 out of 10, Exceptional, (388)
"Great breakfast, clean rooms and beds "
United States
Fabiola B
The price is Rp1.720.963
Rp1.953.292 total
includes taxes & fees
26 Dec - 27 Dec
Hampton Inn & Suites Durham University Medical Center
Courtyard
Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr
3.0 star property
Trinity Park, 3.3 km from Museum of Life and Science
9.2 out of 10, Wonderful, (459)
"Hotel was great - very friendly staff."
United States
Lisa
The price is Rp2.333.306
Rp2.648.302 total
includes taxes & fees
19 Dec - 20 Dec
Residence Inn Durham McPherson/Duke University Medical Cntr
Meeting facility
Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center
3.0 star property
9th Street District, 3.4 km from Museum of Life and Science
9.2 out of 10, Wonderful, (1000)
"Clean rooms, nice staff. Clean hotel. Ample parking. "
United States
Emana
The price is Rp1.605.065
Rp1.821.748 total
includes taxes & fees
19 Dec - 20 Dec
Hilton Garden Inn Durham/University Medical Center
Terrace/patio
JB Duke Hotel

JB Duke Hotel

JB Duke Hotel
4.0 star property
5.6 km from Museum of Life and Science
9.4 out of 10, Exceptional, (536)
"Great service at the front desk and bar. The environment was also very nice. "
United States
Logan David
The price is Rp2.482.364
Rp2.817.483 total
includes taxes & fees
24 Dec - 25 Dec
JB Duke Hotel
Indoor pool
Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club
4.0 star property
5.9 km from Museum of Life and Science
9.4 out of 10, Exceptional, (1002)
"Everything was fabulous. Very relaxing and enjoyable"
United States
William
The price is Rp2.668.160
Rp3.028.360 total
includes taxes & fees
18 Dec - 19 Dec
Washington Duke Inn & Golf Club
Terrace/patio
SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View
3.5 star property
4.6 km from Museum of Life and Science
9.2 out of 10, Wonderful, (451)
"Great room, showers amazing, great staff. "
United States
Micah
The price is Rp1.717.628
Rp1.949.507 total
includes taxes & fees
28 Dec - 29 Dec
SpringHill Suites by Marriott Durham City View
Premium bedding, desk, blackout curtains, iron/ironing board
The Durham Hotel

The Durham Hotel

The Durham Hotel
4.0 star property
Downtown Durham, 3.6 km from Museum of Life and Science
9.0 out of 10, Wonderful, (638)
"Perfect place to stay for an easy walk to see a show at the charming Carolina Theater. Food, service and atmosphere were outstanding. "
United States
Jo
The price is Rp3.101.903
Rp3.520.661 total
includes taxes & fees
13 Dec - 14 Dec
The Durham Hotel
Property amenity
Aloft Durham Downtown

Aloft Durham Downtown

Aloft Durham Downtown
3.0 star property
American Tobacco District, 4.1 km from Museum of Life and Science
9.0 out of 10, Wonderful, (730)
"Very friendly staff, very clean and convenient location"
United States
Robert
The price is Rp3.251.820
Rp3.690.815 total
includes taxes & fees
28 Dec - 29 Dec
Aloft Durham Downtown
BBQ/picnic Area
AC Hotel Durham

AC Hotel Durham

AC Hotel Durham
3.0 star property
4.9 km from Museum of Life and Science
9.0 out of 10, Wonderful, (609)
"Overall great stay "
United States
Sarah
The price is Rp1.970.269
Rp2.236.256 total
includes taxes & fees
19 Dec - 20 Dec
AC Hotel Durham
Daily cooked-to-order breakfast (USD 19.95 per person)
Durham Marriott City Center

Durham Marriott City Center

Durham Marriott City Center
3.5 star property
Downtown Durham, 3.6 km from Museum of Life and Science
8.8 out of 10, Excellent, (822)
"The room was clean. The staff was very helpful and the food was good. "
United States
Tia
The price is Rp2.234.584
Rp2.536.253 total
includes taxes & fees
17 Dec - 18 Dec
Durham Marriott City Center
Front of property – evening/night
University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center
2.0 star property
4 km from Museum of Life and Science
8.8 out of 10, Excellent, (1001)
"The staff was great and very friendly! Everything was very clean! Very nice stay and definitely reasonable rates!"
United States
Doug
The price is Rp1.786.000
Rp2.027.301 total
includes taxes & fees
24 Dec - 25 Dec
University Inn Durham next to Duke University Medical Center
Interior entrance
21c Museum Hotel Durham

21c Museum Hotel Durham

21c Museum Hotel Durham
4.0 star property
Downtown Durham, 3.7 km from Museum of Life and Science
8.4 out of 10, Very good, (1001)
"Overall good hotel and friendly staff. Building and rooms show some age but that is part of the charm. Enjoyable stay. "
United States
Lisa H
The price is Rp2.686.504
Rp3.132.562 total
includes taxes & fees
17 Dec - 18 Dec
21c Museum Hotel Durham
Front of property
The Lodge at Duke Medical Center

The Lodge at Duke Medical Center

The Lodge at Duke Medical Center
3.0 star property
4 km from Museum of Life and Science
8.4 out of 10, Very good, (1001)
"Older property but very convenient and clean for our quick trip. "
United States
Stacie
The price is Rp2.151.204
Rp2.441.618 total
includes taxes & fees
14 Dec - 15 Dec
The Lodge at Duke Medical Center
Property grounds
Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel
4.0 star property
16.3 km from Museum of Life and Science
9.6 out of 10, Exceptional, (1001)
"Friendly staff, beautiful grounds to explore and excellent accommodations."
United States
Jason
The price is Rp2.537.253
Rp2.879.782 total
includes taxes & fees
14 Dec - 15 Dec
Rizzo Center, a Destination by Hyatt Hotel
Seasonal outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas
Hilton Durham near Duke University

Hilton Durham near Duke University

Hilton Durham near Duke University
3.5 star property
5.2 km from Museum of Life and Science
8.4 out of 10, Very good, (1001)
"Great stay"
United States
Daniel
The price is Rp1.763.987
Rp2.002.125 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton Durham near Duke University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Museum of Life and Science Hotel Reviews

Unscripted Durham, Part of JDV by Hyatt

Unscripted Durham, Part of JDV by Hyatt

10/10 Excellent
"Nice"
isaiah 1-night trip
Posted 3 weeks ago
Unscripted Durham, Part of JDV by Hyatt

Hotels near other Museum of Life and Science attractions

Brightleaf Square

You can do some window-shopping at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.
See properties

Vietnam Veterans Living Memorial

You can find out about the history of Durham with a trip to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Museum of Life and Science?
Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, take a look at the 9 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Museum of Life and Science?
Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Holiday Inn Express Durham by IHG and Comfort Inn & Suites Durham near Duke University.
How many hotels can I expect to find close to Museum of Life and Science?
Expedia has 9 hotels and other accommodation options within a mile from Museum of Life and Science.
If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best deals near Museum of Life and Science.
What can I see and do near Museum of Life and Science?
You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium and Wallace Wade Stadium. You can watch performances at Carolina Theatre, Durham Performing Arts Center and Manbites Dog Theater if you're interested in local theatre.

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